Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
PIM2 encodes a protooncogene that acts as a serine/threonine protein kinase. Additionally we are shipping Proto-Oncogene Pim-2 (Serine Threonine Kinase) Antibodies (112) and Proto-Oncogene Pim-2 (Serine Threonine Kinase) Kits (11) and many more products for this protein.
Showing 10 out of 17 products:
Inhibition of the Pim1 (show PIM1 Proteins) oncogene (show RAB1A Proteins) results in diminished visual function.
These results demonstrate the involvement of PIM (show PIM1 Proteins) kinases in LIF (show LIF Proteins)-induced regulation in different trophoblastic cell lines which may indicate similar functions in primary cells.
PIM (show PIM1 Proteins) kinases in classical Hodgkin lymphoma exhibit pleiotropic effects, orchestrating tumor immune escape and supporting Reed-Sternberg cell survival.
High PIM2 expression is associated with osteosarcoma.
We show that Pim2 inhibitors and proteasome inhibitors, such as bortezomib, have additive effects to inhibit the growth of myeloma cells, suggesting that Pim2 could be an interesting target for the treatment of multiple myeloma.
PIM2 gene knockdown enhances the anti-proliferative effect of AZD1208 in non-Hodgkin lymphoma cell line.
A high percentage of urothelial carcinomas express Pim (show PIM1 Proteins) kinases. Pim (show PIM1 Proteins) expression differs in NILG, NIHG, and IHG lesions.
Our findings suggest that Pim-2-mediated aerobic glycolysis is critical for monitoring Warburg effect in colorectal tumor cells, highlighting Pim-2 as a potential metabolic target for colorectal tumor therapy.
our findings will help to uncover novel signaling pathways between inflammations and oxidative stress in rheumatoid arthritis development and imply that Pim-2/mTORC1 pathway may be critical for the initiation of inflammatory reactions.
Persistent activation of STAT3 (show STAT3 Proteins) by PIM2-driven positive feedback loop for epithelial-mesenchymal transition in breast cancer.
Data demonstrate the role of PIM (show PIM1 Proteins) kinases in driving myeloid leukemia (show BCL11A Proteins), and as candidate molecules for therapy against human malignancies.
studies define a pathway for limiting the regulation of Foxp3 (show FOXP3 Proteins) function because the Pim-2 kinase represents a potential therapeutic target for modulating the Treg cell suppressive activities in controlling immune responses
Pim2 facilitated allograft rejection primarily by modulating the apoptosis of effector T cells and the function of regulatory T cells.
Loss of PIM2 is associated with abnormal hematopoietic phenotypes.
signals from IL-7 (show IL7 Proteins) and RAG DSBs activate distinct Pim (show PIM1 Proteins) kinase family members that have context-dependent activities in regulating pre-B cell proliferation and survival.
Targeting cap-dependent translation blocks converging survival signals by AKT (show AKT1 Proteins) and PIM 1 (show PIM1 Proteins), 2 kinases in lymphoma
PIM2 controls the expression of the pro-inflammatory cytokine IL-6 (show IL6 Proteins).
results support the hypothesis that Pim2, which is also a known target of Flt3 (show FLT3 Proteins)-ITD (another gene that cooperates with PML (show PML Proteins)-RARalpha (show RARA Proteins)), cooperates with PRalpha to induce acute promyelocytic leukemia (show PML Proteins)-like disease
Pim-2 is a direct link between growth factor-induced transcription and a novel, kinase-dependent pathway that promotes cell-autonomous survival
pim-2 functions similarly to pim-1 (show PIM1 Proteins) as a pro-survival kinase; BAD is a legitimate PIM-2 substrate
Pim-2 and Akt-1 (show AKT1 Proteins) are critical components of overlapping but independent pathways, either of which is sufficient to promote the growth and survival of nontransformed hematopoietic cells
This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival.
, proviral integration site 2
, serine/threonine-protein kinase Pim-1
, serine/threonine-protein kinase pim-2
, proto-oncogene Pim-2 (serine threonine kinase)
, serine/threonine protein kinase pim-2
, serine/threonine kinase