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anti-Protocadherin 8 (PCDH8) Antibodies

PCDH8 belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. Additionally we are shipping Protocadherin 8 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PCDH8 5100 O95206
PCDH8 18530 Q7TSK3
PCDH8 64865 D3ZE55
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Top anti-Protocadherin 8 Antibodies at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-PCDH8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC (p), RNAi, ELISA, WB Immunoperoxidase of monoclonal antibody to PCDH8 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml] PCDH8 monoclonal antibody (M01), clone 6A8 Western Blot analysis of PCDH8 expression in COLO 320 HSR . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated WB Western blot analysis of PCDH8 over-expressed 293 cell line, cotransfected with PCDH8 Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of PCDH8 expression in transfected 293T cell line by PCDH8 monoclonal antibody (M01), clone 6A8. Lane 1: PCDH8 transfected lysate(113 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$405.17
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Rabbit Un-conjugated WB PCDH8 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated WB PCDH8 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details

PCDH8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Protocadherin 8 Antibodies

  1. Chicken Polyclonal PCDH8 Primary Antibody for WB - ABIN2782184 : Lim, Hao, Shaw, Patel, Szabó, Rual, Fisk, Li, Smolyar, Hill, Barabási, Vidal, Zoghbi: A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. in Cell 2006 (PubMed)

  2. Human Monoclonal PCDH8 Primary Antibody for IHC (p), RNAi - ABIN562128 : Haeberle, Dudley, Liu, Butte, Contag: Identification of cell surface targets through meta-analysis of microarray data. in Neoplasia (New York, N.Y.) 2012 (PubMed)

More Antibodies against Protocadherin 8 Interaction Partners

Xenopus laevis Protocadherin 8 (PCDH8) interaction partners

  1. The transcription factor Snail1 (show SNAI1 Antibodies) is essential for tissue separation, enabling paraxial protocadherin (PAPC) to promote tissue separation through novel functions.

  2. Because PAPC and C-cadherin do not directly interact nor form a joint complex with Fz7, Wnt-11 triggers formation of two distinct complexes that act in parallel to reduce cell adhesion by hampering clustering of C-cadherin.

  3. Data show that PAPC signaling via RhoA (show RHOA Antibodies) and Wnt5a (show WNT5A Antibodies)/Ror2 (show ROR2 Antibodies) activity are required to keep cells aligned in apical-basal orientation during invagination of the ear placode.

  4. Transcriptional regulation of XPAPC by XWnt-5A (show WNT5A Antibodies) requires the receptor tyrosine kinase Ror2 (show ROR2 Antibodies).

  5. ShcA (show SHC1 Antibodies) is required for Wnt-5a (show WNT5A Antibodies)/Ror2 (show ROR2 Antibodies) mediated upregulation of xPAPC, which demonstrates the functional relevance of this interaction.

Human Protocadherin 8 (PCDH8) interaction partners

  1. PCDH8 methylation may be associated with tumor progression and poor prognosis in non-muscle invasive bladder cancer.

  2. PCDH8 methylation may be a useful biomarker to predict the progression of clear cell renal cell carcinoma (show MOK Antibodies).

  3. Loss of the PCDH8 gene is one of the probable causes of psychomotor delay in RB1 (show RB1 Antibodies)-deleted patients.

  4. study demonstrates the epigenetic inactivation of PCDH8 by promoter methylation and its tumor suppressor function in gastric cancer

  5. These results suggest that any contribution of PCDH8 polymorphisms to schizophrenia susceptibility is likely to be weak, although the existence of rare variations of stronger effect cannot be excluded.

  6. Loss of PCDH8 promotes oncogenesis in epithelial human cancers by disrupting cell-cell communication dedicated to tissue organization and repression of mitogenic signaling.

Mouse (Murine) Protocadherin 8 (PCDH8) interaction partners

  1. miR (show MLXIP Antibodies)-429 suppresses the expression of Pcdh8 mRNA and protein.

Protocadherin 8 (PCDH8) Antigen Profile

Protein Summary

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails.

Gene names and symbols associated with anti-Protocadherin 8 (PCDH8) Antibodies

  • protocadherin 8 (PCDH8) antibody
  • protocadherin 8 (pcdh8) antibody
  • protocadherin 8 (Pcdh8) antibody
  • 1700080P15Rik antibody
  • Arcadlin antibody
  • Papc antibody
  • protocadherin-8 antibody
  • xpapc antibody

Protein level used designations for anti-Protocadherin 8 (PCDH8) Antibodies

paraxial protocadherin , paraxial protocadherin 8 short isoform , protocadherin-8 , arcadlin , activity-regulated cadherin-like protein

GENE ID SPECIES
452748 Pan troglodytes
444663 Xenopus laevis
428065 Gallus gallus
5100 Homo sapiens
485469 Canis lupus familiaris
513346 Bos taurus
18530 Mus musculus
64865 Rattus norvegicus
100155738 Sus scrofa
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