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Pyridoxamine 5'-Phosphate Oxidase (PNPO) ELISA Kits

The enzyme encoded by PNPO catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Additionally we are shipping PNPO Antibodies (71) and PNPO Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PNPO 55163 Q9NVS9
PNPO 64533 O88794
PNPO 103711 Q91XF0
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Top PNPO ELISA Kits at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 11 to 13 Days
$875.60
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Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
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Rat
96 Tests Log in to see 11 to 13 Days
$875.60
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Cow
96 Tests Log in to see 11 to 13 Days
$1,029.60
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More ELISA Kits for PNPO Interaction Partners

Human Pyridoxamine 5'-Phosphate Oxidase (PNPO) interaction partners

  1. Exome sequencing revealed that the patient was compound heterozygous for pathogenic mutations [c.546+1G>A (IVS5+1 G>A) and c.620delG (p.G207VfsX215)] in the PNPO gene.

  2. One sequence variant, R116Q, a single nucleotide polymorphism that has been reported in the general population, was found to have an effect on PNPO activity.

  3. Challenge to the paradigm of exclusive PLP (show PLP1 ELISA Kits) responsiveness in patients with pyridoxal 5'-phosphate oxidase deficiency and underlines the importance of consecutive testing of pyridoxine and PLP (show PLP1 ELISA Kits) in neonates with antiepileptic drug-resistant seizures.

  4. Generalized epilepsies implicates susceptibility genes: CHRM3 (show CHRM3 ELISA Kits) at 1q43, VRK2 (show VRK2 ELISA Kits) at 2p16.1, ZEB2 (show ZEB2 ELISA Kits) at 2q22.3, SCN1A (show SCN1A ELISA Kits) at 2q24.3 and PNPO at 17q21.32.

  5. provide evidence that a single arginine residue of the C terminus of pyridoxal 5'-phosphate synthase is responsible for coordinating co-operativity in this elaborate protein machinery

  6. Results describe a combined computer and biochemical approach to characterize human pyridoxine 5'-phosphate oxidase (PNPO).

  7. We examined 8 single nucleotide polymorphisms (SNPs) in PNPO and its 5'-flanking regions in 359 schizophrenia patients and 582 control subjects.

  8. Sequencing of the PNPO gene revealed a novel homozygous nonsense mutationt in exon 3 in the neonatal and infantile seizure.

  9. PNP (show NP ELISA Kits) oxidase R229W mutation identified in patients with neonatal epileptic encephalopathy sgnificantly affect the catalytic efficiency of the enzyme.

PNPO Antigen Profile

Antigen Summary

The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy.

Gene names and symbols associated with PNPO

  • pyridoxine 5'-phosphate oxidase (pnpo) antibody
  • pyridoxine 5'-phosphate oxidase (pdxH) antibody
  • pyridoxamine 5'-phosphate oxidase (Mrub_2888) antibody
  • pyridoxamine 5'-phosphate oxidase (Arnit_1624) antibody
  • pyridoxamine 5'-phosphate oxidase (Ndas_4168) antibody
  • pyridoxamine 5'-phosphate oxidase (Mesil_2817) antibody
  • Pyridoxamine 5'-phosphate oxidase (Isop_0296) antibody
  • Pyridoxamine 5'-phosphate oxidase (Despr_1960) antibody
  • Pyridoxamine 5'-phosphate oxidase (Pedsa_1348) antibody
  • pyridoxamine 5'-phosphate oxidase (Mesop_5639) antibody
  • pyridoxamine 5'-phosphate oxidase (PNPO) antibody
  • pyridoxamine 5'-phosphate oxidase (Pnpo) antibody
  • pyridoxine 5'-phosphate oxidase (Pnpo) antibody
  • AI415282 antibody
  • ECK1634 antibody
  • im:7138360 antibody
  • JW1630 antibody
  • PDXPO antibody

Protein level used designations for PNPO

pyridoxine-5'-phosphate oxidase , pyridoxamine 5'-phosphate oxidase , Pyridoxamine 5'-phosphate oxidase , pyridoxal 5'-phosphate synthase , pyridoxamine-phosphate oxidase , pyridoxine 5'-phosphate oxidase , pyridoxine 5-phosphate oxidase

GENE ID SPECIES
402868 Danio rerio
946806 Escherichia coli str. K-12 substr. MG1655
8881004 Meiothermus ruber DSM 1279
9171784 Arcobacter nitrofigilis DSM 7299
9248042 Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111
9252339 Meiothermus silvanus DSM 9946
10154400 Isosphaera pallida ATCC 43644
10174688 Desulfobulbus propionicus DSM 2032
10230903 Pedobacter saltans DSM 12145
10829504 Mesorhizobium opportunistum WSM2075
55163 Homo sapiens
480540 Canis lupus familiaris
512573 Bos taurus
64533 Rattus norvegicus
103711 Mus musculus
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