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Pyrin and HIN Domain Family, Member 1 Proteins (PYHIN1)

The protein encoded by PYHIN1 belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. Additionally we are shipping PYHIN1 Antibodies (29) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PYHIN1 149628 Q6K0P9
PYHIN1 236312 Q8BV49
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Top PYHIN1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

PYHIN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Pyrin and HIN Domain Family, Member 1 (PYHIN1) Interaction Partners

Human Pyrin and HIN Domain Family, Member 1 (PYHIN1) interaction partners

  1. a new member of the hematopoietic interferon (show IFNA Proteins) (IFN)-inducible nuclear protein (show RDBP Proteins). Six different alternatively spliced forms are transcribed from the IFIX gene

  2. IFIX alpha1 isoform functions as a tumor suppressor by repressing HDM2 function

  3. IFIXalpha suppressed the invasion activity of MDA-MB-468 breast cancer cells, and its inhibitory effect was reversed by the knockdown of maspin (show SERPINB5 Proteins)

Mouse (Murine) Pyrin and HIN Domain Family, Member 1 (PYHIN1) interaction partners

  1. promotes LPS (show TLR4 Proteins)-induced IFN-beta (show IFNB1 Proteins) and NO production in macrophages

PYHIN1 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2, which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with PYHIN1

  • pyrin and HIN domain family, member 1 (PYHIN1)
  • pyrin and HIN domain family, member 1 (Pyhin1)
  • 4930422C14 protein
  • AI447904 protein
  • Ifi209 protein
  • Ifix protein
  • RP11-520H16.1 protein

Protein level used designations for PYHIN1

pyrin and HIN domain family, member 1 , interferon-inducible protein X , pyrin and HIN domain-containing protein 1 , ifi-209 , interferon-inducible protein 209 , interferon-inducible protein p209

GENE ID SPECIES
469842 Pan troglodytes
149628 Homo sapiens
236312 Mus musculus
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