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The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. Additionally we are shipping RAB17 Antibodies (80) and many more products for this protein.
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Human RAB17 Protein expressed in Escherichia coli (E. coli) - ABIN667487
Hunziker, Peters: Rab17 localizes to recycling endosomes and regulates receptor-mediated transcytosis in epithelial cells. in The Journal of biological chemistry 1998
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The selectivity in syntaxin binding and apical protein redistribution further suggests that rab17 and syntaxin 2 (show STX2 Proteins) mediate fusion of transcytotic vesicles at the apical surface.
Rabex-5 (show RABGEF1 Proteins) regulates neurite morphogenesis of hippocampal neurons by activating at least two downstream targets, Rab5 (show RAB5A Proteins), which is localized in both axons and dendrites, and Rab17, which is localized in dendrites alone
Rab17 regulates dendritic morphogenesis and postsynaptic development of hippocampal neurons.
Data reveal new functions for recycling endosomes and Rab17 in pigmentation through a distal step in the process of melanosome release via filopodia.
Down-regulation of Rab17 promotes tumourigenic properties of hepatocellular carcinoma cells via Erk MAPK (show MAPK1 Proteins) signaling.
Rab17 might act as a tumour suppressor gene in hepatocellular carcinoma , and the anti-tumour effects of Rab17 might be partially mediated by the Erk (show EPHB2 Proteins) pathway.
These results suggest that Rab17 and Rab17-mediated REs are involved in Streptococcus pyogenes-containing autophagosome-like vacuole formation.
Knockdown of either Rab17 or liprin (show PPFIA1 Proteins)-beta2 restores invasiveness of ERK2 (show MAPK1 Proteins)-depleted cells, indicating that ERK2 (show MAPK1 Proteins) drives invasion of MDA-MB-231 cells by suppressing expression of these genes.
The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an epithelial cell-specific GTPase (Lutcke et al., 1993
, RAB17, member RAS oncogene family
, ras-related protein Rab-17