anti-RAP1, GTP-GDP Dissociation Stimulator 1 (RAP1GDS1) Antibodies

The smg GDP dissociation stimulator (smgGDS) protein is a stimulatory GDP/GTP exchange protein with GTPase activity (Riess et al., 1993 [PubMed 8262526]).[supplied by OMIM, Feb 2010].. Additionally we are shipping RAP1GDS1 Kits (5) and RAP1GDS1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RAP1GDS1 310909  
RAP1GDS1 5910 P52306
RAP1GDS1 229877  
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Top anti-RAP1GDS1 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB RAP1GDS1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RAP1GDS1 Antibody (Center) for immunohistochemistry.  Clinical relevance has not been evaluated. RAP1GDS1 Antibody (Center)  western blot analysis in HepG2,MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RAP1GDS1 antibody detected the RAP1GDS1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin fixed, paraffin embedded human brain tissue stained with RAP1GDS1 Antibody  followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of RAP1GDS1 Antibody  in HepG2,MDA-MB231 cell line lysates (35ug/lane). This demonstrates the RAP1GDS1 antibody detected the RAP1GDS1 protein (arrow 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB Host: Rabbit  Target Name: RAP1GDS1  Sample Tissue: Human Fetal Heart  Antibody Dilution: 1.0 µg/mL Host: Rabbit  Target Name: RAP1GDS1  Sample Tissue: Human Fetal Brain  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: RAP1GDS1 Antibody [NBP1-87027] - Immunofluorescent staining of human cell line A-431 shows positivity in cytoplasm. Western Blot: RAP1GDS1 Antibody [NBP1-87027] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue.Lane 6: Human tonsil tissue 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: NT2D1 B: PC-3 7.5% SDS PAGE antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded U373 xenograft, using RAP1GDS1, antibody at 1:500 dilution. 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: RAP1GDS1 Antibody [NBP2-20073] - Sample (30 ug of whole cell lysate) A: NT2D1 B: PC-3 7. 5% SDS PAGE gel, diluted at 1:1000. Immunohistochemistry-Paraffin: RAP1GDS1 Antibody [NBP2-20073] - Immunohistochemical analysis of paraffin-embedded U373 xenograft, using antibody at 1:500 dilution. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB Western Blot: RAP1GDS1 Antibody [NBP1-69099] - Human lacenta Lysate 1ug/ml Gel Concentration 12% Western Blot: RAP1GDS1 Antibody [NBP1-69099] - Human Jurkat, Antibody Dilution: 1.0 ug/ml RAP1GDS1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells. 100 μL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated IHC (p), WB   400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

RAP1GDS1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Human ,
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Mouse (Murine) ,


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Top referenced anti-RAP1GDS1 Antibodies

  1. Human Polyclonal RAP1GDS1 Primary Antibody for EIA, IHC (p) - ABIN954453 : Zemunik, Boban, Lauc, Janković, Rotim, Vatavuk, Bencić, Dogas, Boraska, Torlak, Susac, Zobić, Rudan, Pulanić, Modun, Mudnić, Gunjaca, Budimir, Hayward, Vitart, Wright, Campbell, Rudan: Genome-wide association study of biochemical traits in Korcula Island, Croatia. in Croatian medical journal 2009 (PubMed)
    Show all 5 references for 954453

  2. Human Polyclonal RAP1GDS1 Primary Antibody for IHC (p), WB - ABIN655886 : Schönherr, Yang, Vigny, Palmer, Hallberg: Anaplastic lymphoma kinase activates the small GTPase Rap1 via the Rap1-specific GEF C3G in both neuroblastoma and PC12 cells. in Oncogene 2010 (PubMed)
    Show all 3 references for 655886

  3. Human Polyclonal RAP1GDS1 Primary Antibody for ICC, IF - ABIN4349352 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

More Antibodies against RAP1GDS1 Interaction Partners

Human RAP1, GTP-GDP Dissociation Stimulator 1 (RAP1GDS1) interaction partners

  1. Data suggest that SmgGDS-558 splice variant exhibits a fold containing tandem copies of armadillo (show PKP1 Antibodies)-repeat motifs not present in other guanine nucleotide exchange factors (GEFs); SmgGDS harbors distinct positively and negatively charged regions, both of which play critical roles in binding to RhoA (show RHOA Antibodies) and in GEF (show SLC2A4RG Antibodies) activity. (SmgGDS = smg (show SNRPG Antibodies) p21 (show CDKN1A Antibodies) stimulatory GDP exchange protein; RhoA (show RHOA Antibodies) = ras homolog gene family, member A (show CXCL14 Antibodies))

  2. Unlike Rap1B (show RAP1B Antibodies), phosphorylation in the polybasic region of Rap1A (show RAP1A Antibodies) does not detectably inhibit its prenylation or its binding to SmgGDS-607.

  3. In addition, a PINK1 (show PINK1 Antibodies) mutant, which induced mitochondrial enlargement and had been considered as a Drosophila model of Parkinson's disease (PD), caused fly muscle defects, and the loss of vimar could rescue these defects. Furthermore, we found that the mammalian homolog of Vimar, RAP1GDS1, played a similar role in regulating mitochondrial morphology, suggesting a functional conservation of this GEF (show SLC2A4RG Antibodies) member.

  4. results indicate that statins selectively up-regulate SmgGDS in endothelial cells, for which the beta1-integrin/Akt1 (show AKT1 Antibodies) pathway may be involved, demonstrating the novel aspects of the pleiotropic effects of statins

  5. DiRas1 (show DIRAS1 Antibodies) expression inhibits malignant features of cancers in part by nonproductively binding to SmgGDS and inhibiting the binding of other small GTPases to SmgGDS

  6. SmgGDS promotes cell cycle progression in multiple types of cancer, making SmgGDS a valuable target for cancer therapeutics.

  7. TG2 (show TGM2 Antibodies) contributes to apoptosis induction in Jurkat T cells by modulating Ca2 (show CA2 Antibodies)+ homeostasis via cross-linking RAP1GDS1.

  8. findings identify SmgGDS-558 as an activator of RhoA (show RHOA Antibodies) and NF-kB in breast cancer, and demonstrate a functional role for SmgGDS-558 in the proliferation of breast cancer cells and tumorigenesis.

  9. this study provides evidence that SmgGDS-607 associates with GTPases through recognition of the last amino acid in the CAAX motif.

  10. These results indicate that statins exert their pleiotropic effects through SmgGDS upregulation with a resultant Rac1 degradation and reduced oxidative stress in animals and humans.

Cow (Bovine) RAP1, GTP-GDP Dissociation Stimulator 1 (RAP1GDS1) interaction partners

  1. These results identify SmgGDS as a novel regulator of myosin organization and contraction in vascular smooth muscle cells.

Mouse (Murine) RAP1, GTP-GDP Dissociation Stimulator 1 (RAP1GDS1) interaction partners

  1. results indicate that statins selectively up-regulate SmgGDS in endothelial cells, for which the beta1-integrin/Akt1 (show AKT1 Antibodies) pathway may be involved, demonstrating the novel aspects of the pleiotropic effects of statins

  2. These results indicate that statins exert their pleiotropic effects through SmgGDS upregulation with a resultant Rac1 degradation and reduced oxidative stress in animals and humans.

RAP1GDS1 Antigen Profile

Protein Summary

The smg GDP dissociation stimulator (smgGDS) protein is a stimulatory GDP/GTP exchange protein with GTPase activity (Riess et al., 1993

Gene names and symbols associated with RAP1GDS1

  • RAP1, GTP-GDP dissociation stimulator 1 (Rap1gds1) antibody
  • RAP1, GTP-GDP dissociation stimulator 1 (LOC100217715) antibody
  • RAP1, GTP-GDP dissociation stimulator 1 (RAP1GDS1) antibody
  • RAP1, GTP-GDP dissociation stimulator 1 (rap1gds1-a) antibody
  • BC011279 antibody
  • gds1 antibody
  • rap1gds1 antibody
  • smgGDS antibody
  • XsmgGDS antibody

Protein level used designations for RAP1GDS1

rap1 GTPase-GDP dissociation stimulator 1 , RAP1, GTP-GDP dissociation stimulator 1 , SMG GDS protein , SMG P21 stimulatory GDP/GTP exchange protein , exchange factor smgGDS , ralB-binding protein A , rap1 GTPase-GDP dissociation stimulator 1-A , smgGDS-A , xsmgGDS-A

GENE ID SPECIES
310909 Rattus norvegicus
100217715 Taeniopygia guttata
5910 Homo sapiens
282516 Bos taurus
229877 Mus musculus
394369 Xenopus laevis
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