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anti-Receptor Protein Tyrosine Phosphatase (PTPRT) Antibodies

The protein encoded by PTPRT is a member of the protein tyrosine phosphatase (PTP) family. Additionally we are shipping PTPRT Proteins (6) and PTPRT Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTPRT 11122 O14522
PTPRT 19281 Q99M80
PTPRT    
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Top anti-PTPRT Antibodies at antibodies-online.com

Showing 10 out of 25 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN185288 staining (0.3µg/ml) of Human Brain lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with PTPRT antibody ABIN337325 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$463.83
Details
Human Goat Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Goat APC ELISA, WB   100 μL Log in to see 16 Days
$713.43
Details

PTPRT Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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,
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Mouse (Murine) ,
,

Guinea Pig


Top referenced anti-PTPRT Antibodies

  1. Human Polyclonal PTPRT Primary Antibody for ELISA, WB - ABIN185288 : Wang, Shen, Parsons, Bardelli, Sager, Szabo, Ptak, Silliman, Peters, van der Heijden, Parmigiani, Yan, Wang, Riggins, Powell, Willson, Markowitz, Kinzler, Vogelstein, Velculescu: Mutational analysis of the tyrosine phosphatome in colorectal cancers. in Science (New York, N.Y.) 2004 (PubMed)

More Antibodies against PTPRT Interaction Partners

Human Receptor Protein Tyrosine Phosphatase (PTPRT) interaction partners

  1. PTPRT promoter methylation is significantly associated with sensitivity to STAT3 (show STAT3 Antibodies) inhibition in HNSCC cells, suggesting that PTPRT promoter methylation may serve as a predictive biomarker for responsiveness to STAT3 (show STAT3 Antibodies) inhibitors in clinical development

  2. Data reported evidence that rs2866943 polymorphism in PTPRT 3'-UTR (show UTS2R Antibodies) was involved in the occurrence of esophageal squamous cell carcinoma by acting as a protective factor while rs6029959 acts as a risk factor.

  3. Data show that hepatitis B virus X protein mutant HBxDelta127 enhances proliferation of hepatoma cells through up-regulating miR (show MLXIP Antibodies)-215 targeting protein tyrosine phosphatase (show ACP1 Antibodies), receptor type T (PTPRT).

  4. tumor-specific mutational events in the PTPRT gene can serve as direct drivers for tumor growth by inducing hyperactivation of STAT3 (show STAT3 Antibodies), a potent oncogenic transcription factor and PTPRT substrate

  5. [review] High-throughput mutational analysis identifies loss-of-function mutations in six PTPs (show PTS Antibodies) in human colon cancers, providing critical cancer genetics evidence that PTPs (show PTS Antibodies) can act as tumour suppressor genes.

  6. Data show that paxillin (show PXN Antibodies) is a direct substrate of PTPRT and that PTPRT specifically regulates paxillin (show PXN Antibodies) phosphorylation at tyrosine residue 88(Y88).

  7. alterations of the PTPRT-mediated signaling pathway by PTPRT phosphatase domain mutation may not play a critical role in the development of common human cancers

  8. STAT3 (show STAT3 Antibodies) is a substrate of receptor protein tyrosine phosphatase T

  9. brain-specific (show CALY Antibodies) PTPRT regulates synapse formation through interaction with cell adhesion molecules, and this function and the phosphatase activity are attenuated through tyrosine phosphorylation by the synaptic tyrosine kinase (show TXK Antibodies) Fyn (show FYN Antibodies).

Mouse (Murine) Receptor Protein Tyrosine Phosphatase (PTPRT) interaction partners

  1. Receptor protein tyrosine phosphatase rho (RPTPrho, gene symbol PTPRT) is a transmembrane protein expressed at high levels in the developing hippocampus, olfactory bulb, cortex, and cerebellum.

  2. These studies implicate PTPRT-modulated STAT3 (show STAT3 Antibodies) signaling in the regulation of high-fat diet-induced obesity

  3. BCR (show BCR Antibodies) is a novel substrate of PTPRT .

  4. Data show that paxillin (show PXN Antibodies) is a direct substrate of PTPRT and that PTPRT specifically regulates paxillin (show PXN Antibodies) phosphorylation at tyrosine residue 88(Y88).

PTPRT Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

Gene names and symbols associated with PTPRT

  • protein tyrosine phosphatase, receptor type, T (PTPRT) antibody
  • protein tyrosine phosphatase, receptor type, T (Ptprt) antibody
  • mKIAA0283 antibody
  • RPTP-rfo antibody
  • RPTPrho antibody

Protein level used designations for PTPRT

R-PTP-T , RPTP-rho , receptor protein tyrosine phosphatase , receptor-type tyrosine-protein phosphatase T , receptor-type tyrosine-protein phosphatase rho , RPTPmam4 , mRPTPrho , receptor protein tyrosine phosphatase-rho

GENE ID SPECIES
11122 Homo sapiens
19281 Mus musculus
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