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anti-Regulator of G-Protein Signaling 4 (RGS4) Antibodies

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. Additionally we are shipping RGS4 Kits (28) and RGS4 Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RGS4 5999 P49798
RGS4 19736 O08899
RGS4 29480 P49799
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Top anti-RGS4 Antibodies at antibodies-online.com

Showing 10 out of 65 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RGS4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate WB Suggested Anti-RGS4  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of RGS4 Antibody (Center) (ABIN652827) in MDA-MB231 cell line lysates (35 µg/lane). RGS4 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of RGS4 Antibody (Center) (ABIN652827) in mouse brain tissue lysates (35 µg/lane). RGS4 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-RGS4 AntibodyTitration: 1.0 µg/mL  Positive Control: HepG2 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC (p), WB AP31123PU-N RGS4 antibody staining of Paraffin-Embedded Breast Carcinoma at 1/500 dilution. AP31123PU-N RGS4 antibody staining of Paraffin-Embedded Muscle at 1/500 dilution. 0.1 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC (p), WB Testis 50 μg Log in to see 8 to 10 Days
$676.50
Details
Cow Rabbit Un-conjugated WB Western blot analysis of RGS4 expression in HepG2 (A), SP2/0 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Chicken Un-conjugated WB 0.05 mg Log in to see 2 to 3 Days
$412.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of RGS4 expression in transfected 293T cell line by RGS4 monoclonal antibody (M01), clone 2B2. Lane 1: RGS4 transfected lysate(23.3 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

RGS4 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-RGS4 Antibodies

  1. Cow (Bovine) Polyclonal RGS4 Primary Antibody for WB - ABIN2779301 : Ishii, Ikushima, Kurachi: In vivo interaction between RGS4 and calmodulin visualized with FRET techniques: possible involvement of lipid raft. in Biochemical and biophysical research communications 2005 (PubMed)

  2. Human Polyclonal RGS4 Primary Antibody for WB - ABIN652827 : Heximer, Watson, Linder, Blumer, Hepler: RGS2/G0S8 is a selective inhibitor of Gqalpha function. in Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)

More Antibodies against RGS4 Interaction Partners

Human Regulator of G-Protein Signaling 4 (RGS4) interaction partners

  1. All of these results confirmed the critical role of RGS4 in NSCLC progression.

  2. After alphao dissociates from MOR, RGS4 remains bound to the C-terminal region of MOR

  3. RGS4 deletion results in a predisposition to atrial fibrillation from enhanced activity in the G-protein pathway, resulting in abnormal calcium release and corresponding electrical events.

  4. RGS2 and RGS4 are new interacting partners that play key roles in G protein coupling to negatively regulate kappa-OmicronR signaling.

  5. RGS4 and COMT (show COMT Antibodies) risk variants are associated with brain structural alterations in patient with schizophrenia.

  6. genetic association study in Chinese Han population: Data suggest an SNP in RGS4 (rs10759) is associated with increased predisposition to schizophrenia via down-regulation of miroRNA (MIRN124) binding to 3-prime-untranslated region of RGS4 mRNA.

  7. ectopic expression of R4 subfamily members RGS2 (show RGS2 Antibodies), RGS3 (show RGS3 Antibodies), RGS4, and RGS5 (show RGS5 Antibodies) reduced activated PAR1 (show MARK2 Antibodies) wild-type signaling, whereas signaling by the PAR1 (show MARK2 Antibodies) AKKAA mutant was minimally affected.

  8. Data indicate that Rab5 (show RAB5A Antibodies), Rab7 (show RAB7B Antibodies) and Rab11 (show RAB11A Antibodies) are involved in RGS4 traffics through plasma membrane recycling or endosome.

  9. The results suggest unaltered membrane RGS4 and cytosolic RGS10 (show RGS10 Antibodies) proteins levels in schizophrenia and major depression.

  10. dramatic up-regulation of RGS4 expression in the nucleus accumbens of subjects treated with monoamine-directed antidepressants

Rabbit Regulator of G-Protein Signaling 4 (RGS4) interaction partners

  1. Activation of MEKK1 (show MAP3K1 Antibodies)-MKK4 (show MAP2K4 Antibodies)-JNK (show MAPK8 Antibodies)-AP1 (show JUN Antibodies) signaling pathway plays a tonic inhibitory role in regulating Rgs4 transcription in rabbit colonic smooth muscle cells.

  2. These findings suggest that 3'-most AU-rich elements sites within RGS4 3'-UTR (show UTS2R Antibodies) are essential for the instability of RGS4 mRNA.

  3. The 5'-untranslated region (UTR (show UTS2R Antibodies)) extended 120 bp nucleotides upstream of the Rgs4 start codon; a putative promoter sequence (1389 bp) showed a consensus TATA box and cis (show CISH Antibodies)-acting binding sites for several potential transcriptional factors.

  4. The canonical IKK2 (show IKBKB Antibodies)/IkappaBalpha (show NFKBIA Antibodies) pathway of NF-kappaB (show NFKB1 Antibodies) activation mediates the up-regulation of RGS4 expression in response to IL-1beta (show IL1B Antibodies).

  5. Upregulation of RGS4 expression by IL-1beta (show IL1B Antibodies) in colonic smooth muscle is enhanced by ERK1/2 (show MAPK1/3 Antibodies) and p38 MAPK (show MAPK14 Antibodies) and inhibited by the PI3K/Akt (show AKT1 Antibodies)/GSK3beta (show GSK3b Antibodies) pathway.

Mouse (Murine) Regulator of G-Protein Signaling 4 (RGS4) interaction partners

  1. RGS4 in the paraventricular nucleus regulates blood corticosteroid-related GABAB receptor signaling during the acute stress response.

  2. Thus, RGS4 expression, specific to renal vascular smooth muscle cells, inhibits angiotensin II-mediated cytokine signaling and macrophage recruitment during reperfusion, distinct from vasomotor regulation.

  3. Spinal RGS4 inhibited the endogenous or exogenous OR-mediated antinociceptive effect in the formalin pain test.

  4. RGS6 (show RGS6 Antibodies)-Gbeta5 (show GNB5 Antibodies), but not RGS4, is the primary RGS (show PITX2 Antibodies) modulator of parasympathetic HR regulation and SAN M2R-IKACh signaling in mice.

  5. dramatic up-regulation of RGS4 expression in the nucleus accumbens of mice treated with monoamine-directed antidepressants

  6. RGS4 expression in mouse embryo is regulated by Lmx1a (show LMX1A Antibodies) transcription factor.

  7. A novel nitric oxide-RGS4 signal pathway mechanism that couples cardiac vessel growth with myocyte growth and heart size.

  8. Findings support the concept that the inhibitory effects of SPL (show SGPL1 Antibodies) on M3R (show CHRM3 Antibodies) activity are mediated by RGS4.

  9. Rgs4 is expressed in endocrine progenitors of both zebrafish and mouse, and its expression in the mouse pancreatic epithelium is strictly dependent upon Ngn3 (show NEUROG3 Antibodies), and loss of function of Rgs4 results in islet fragmentation in both organisms.

  10. RGS4 antagonizes the development of renal dysfunction in response to ischemia reperfusion injury.

RGS4 Antigen Profile

Protein Summary

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with RGS4

  • regulator of G-protein signaling 4 (RGS4) antibody
  • regulator of G-protein signaling 4 (Rgs4) antibody
  • AA004315 antibody
  • AA597169 antibody
  • ESTM48 antibody
  • ESTM50 antibody
  • RGP4 antibody
  • SCZD9 antibody

Protein level used designations for RGS4

schizophrenia disorder 9 , regulator of G-protein signalling 4 , RGP4

GENE ID SPECIES
5999 Homo sapiens
488666 Canis lupus familiaris
617437 Bos taurus
100009014 Oryctolagus cuniculus
19736 Mus musculus
29480 Rattus norvegicus
100717645 Cavia porcellus
100157437 Sus scrofa
100381246 Ovis aries
378901 Gallus gallus
100172418 Pongo abelii
Selected quality suppliers for anti-RGS4 (RGS4) Antibodies
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