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Regulator of G-Protein Signaling 5 Proteins (RGS5)

RGS5 encodes a member of the regulators of G protein signaling (RGS) family. Additionally we are shipping RGS5 Antibodies (84) and RGS5 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RGS5 8490 O15539
RGS5 19737 O08850
RGS5 54294 P49800
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Top RGS5 Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,427.33
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,427.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,427.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$364.64
Details

RGS5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced RGS5 Proteins

  1. Human RGS5 Protein expressed in Escherichia coli (E. coli) - ABIN667524 : Hepler: Emerging roles for RGS proteins in cell signalling. in Trends in pharmacological sciences 1999 (PubMed)
    Show all 2 references for ABIN667524

More Proteins for Regulator of G-Protein Signaling 5 (RGS5) Interaction Partners

Human Regulator of G-Protein Signaling 5 (RGS5) interaction partners

  1. The rs16849802 of RGS5 and haplotype GAA (show GAA Proteins) independently increased the risk of essential hypertension in Mongolian patients, and may be used as a risk factor for the prediction of high blood pressure.

  2. Downregulation of RGS5 is an important prerequisite for smooth muscle cell proliferation in vascular injury model.

  3. The pericyte marker RGS5 may be of future clinical utility for the evaluation of pericytic differentiation in soft tissue tumors.

  4. RGS5 enhanced the cytotoxic effect of radiation in the human lung cancer cells. Our results indicated that RGS5 may be a potential target for cancer therapy.

  5. Our work identifies a new genetic variant in RGS5 demonstrating additive effect with PDE4D (show PDE4D Proteins), both implicated in modulation of asthma treatment.

  6. ectopic expression of R4 subfamily members RGS2 (show RGS2 Proteins), RGS3 (show RGS3 Proteins), RGS4 (show RGS4 Proteins), and RGS5 reduced activated PAR1 (show MARK2 Proteins) wild-type signaling, whereas signaling by the PAR1 (show MARK2 Proteins) AKKAA mutant was minimally affected.

  7. RGS1 (show RGS1 Proteins) is largely upregulated, whereas RGS2 (show RGS2 Proteins) is downregulated in the majority of solid tumors, whereas RGS5 transcripts are greatly increased in eight subtypes of lymphoma with no reports of downregulation in hematological malignancies

  8. Over-expression of regulator of G protein signaling 5 promotes tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma cells.

  9. demonstrate RGS5 in the blood vessels of other cancer models endowed with a proangiogenic environment, such as human melanoma and renal carcinoma xenografts

  10. Low expression of RGS5 was strongly associated with cancer vasculature invasion and lymph node metastasis in non-small cell lung cancer.

Mouse (Murine) Regulator of G-Protein Signaling 5 (RGS5) interaction partners

  1. RGS5 deletion accelerated development of atherosclerosis and decreased the stability of atherosclerotic plaques partly through activating NF-kappaB and the MEK-ERK1/2 signalling pathways

  2. These studies show that RGS5 protects cardiomyocytes against apoptosis during myocardial ischemia-reperfusion injury through inhibiting both JNK1 (show MAPK8 Proteins)/2 and p38 (show CRK Proteins) signaling pathways.

  3. Downregulation of RGS5 is an important prerequisite for smooth muscle cell proliferation in vascular injury model.

  4. findings highlight a key role of RGS5 at the interface between AngII and PPAR (show PPARA Proteins) signaling

  5. we demonstrate that RGS5 is a critical regulator of GPCR (show GPBAR1 Proteins) signaling in HSCs and regulates HSC (show FUT1 Proteins) activation and fibrogenesis in liver injury.

  6. Collectively, these findings establish RGS5 as a novel determinant of arteriogenesis which shifts G-protein signalling from Galphaq (show GNAQ Proteins)/11-mediated calcium-dependent contraction towards Galpha12/13-mediated Rho kinase (show ROCK2 Proteins)-dependent smooth muscle cell activation.

  7. Loss of RGS5 promotes airway hyperresponsiveness in the absence of allergic inflammation.

  8. study concludes that RGS5 is an endogenous regulator of Hh-mediated signaling

  9. Regulator of G-protein signaling 5 controls blood pressure homeostasis and vessel wall remodeling.

  10. Rgs5 is an important regulator of arrhythmogenesis in the mouse atrium and that the enhanced susceptibility to atrial tachyarrhythmias in Rgs5(-/-) mice may contribute to abnormalities of atrial repolarization.

RGS5 Protein Profile

Protein Summary

This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants have been identified.

Gene names and symbols associated with RGS5

  • regulator of G-protein signaling 5 (RGS5)
  • regulator of G-protein signaling 5a (rgs5a)
  • regulator of G-protein signaling 5 (rgs5)
  • regulator of G-protein signaling 5 (Rgs5)
  • 1110070A02Rik protein
  • fj30h05 protein
  • MGC147439 protein
  • MST092 protein
  • MST106 protein
  • MST129 protein
  • MSTP032 protein
  • MSTP092 protein
  • MSTP106 protein
  • MSTP129 protein
  • rgs5 protein
  • wu:fj30h05 protein
  • xrgs5 protein
  • zgc:64006 protein

Protein level used designations for RGS5

regulator of G-protein signaling 5 , regulator of G-protein signalling 5 , regulator of G protein signaling 5

GENE ID SPECIES
457471 Pan troglodytes
573765 Danio rerio
769998 Gallus gallus
780219 Xenopus (Silurana) tropicalis
100380975 Xenopus laevis
8490 Homo sapiens
488667 Canis lupus familiaris
397640 Sus scrofa
540509 Bos taurus
19737 Mus musculus
54294 Rattus norvegicus
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