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Mediates transcriptional and post-transcriptional regulation of SLC5A1. Additionally we are shipping RSC1A1 Antibodies (14) and RSC1A1 Kits (3) and many more products for this protein.
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Binding of RS1 (show RS1 Proteins)-Reg (show EXTL3 Proteins) to ODC1 (show ODC1 Proteins) inhibits the enzymatic activity at low intracellular glucose, which is blunted at high intracellular glucose.
Taken together, these data indicate that RSC1A1 modulates dynamin-dependent trafficking of intracellular vesicles containing hSGLT1 in Xenopus oocytes, and modulates PKC-dependent short-term regulation of this transporter.
hRS1 protein exhibits glucose-dependent, short-term inhibition of hSGLT1 and hOCT2 (show SLC22A2 Proteins) by inhibiting the release of vesicles from the trans-Golgi network
RS1 (show RS1 Proteins) inhibits the dynamin (show DNM1 Proteins)-dependent release of SGLT1 (show SLC5A1 Proteins)-containing vesicles from the trans-golgi network
RSC1A1 codes for a 67-kDa protein named RS1 (show RS1 Proteins) that mediates transcriptional and post-transcriptional regulation of Na(+)-D-glucose cotransporter SGLT1 (show SLC5A1 Proteins).
Rsc1A1 has a role in Na+-D-glucose cotransport in the small intestine through SGLT1 (show SLC5A1 Proteins) and in preventing obesity [Rsc1A1]
Novel shuttling domain in a regulator (RSC1A1) of transporter SGLT1 (show SLC5A1 Proteins) steers cell cycle-dependent nuclear location.
Mediates transcriptional and post-transcriptional regulation of SLC5A1. Inhibits a dynamin and PKC-dependent exocytotic pathway of SLC5A1. Also involved in transcriptional regulation of SLC22A2. Exhibits glucose-dependent, short-term inhibition of SLC5A1 and SLC22A2 by inhibiting the release of vesicles from the trans-Golgi network (By similarity).
regulatory solute carrier protein, family 1, member 1
, DDI1, DNA-damage inducible 1, homolog 2
, regulatory solute carrier protein family 1 member 1
, transporter regulator RS1
, regulatory subunit of SGLT1
, beta-subunit of Na/D-glucose cotransporter
, sodium-D-glucose cotransporter