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Replication Initiator 1 Proteins (REPIN1)

Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication. Additionally we are shipping REPIN1 Kits (12) and REPIN1 Antibodies (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
REPIN1 29803 Q9BWE0
REPIN1 58887 Q5U4E2
REPIN1 445541 Q68H95
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Top REPIN1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,567.67
Details

REPIN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Replication Initiator 1 (REPIN1) Interaction Partners

Human Replication Initiator 1 (REPIN1) interaction partners

  1. Results show that breast cancer cells underwent epithelial-mesenchymal transition when AP4 was upregulated, and that AP4 regulated p53 (show TP53 Proteins) expression level suggesting AP4 can regulate cell migration via the activity of p53 (show TP53 Proteins).

  2. AP4 is transcriptionally activated by TGFB1 to inhibit phosphorylation of SMAD2 as a negative regulator of an activated TGFB receptor signaling on cell growth inhibition in non-small cell lung cancer

  3. there is a p53 (show TP53 Proteins)-induced double-negative feedback loop involving miR (show MLXIP Proteins)-15a/16-1 and AP4 that stabilizes epithelial and mesenchymal states, respectively, which may determine metastatic prowess in colorectal cancer

  4. a potential role for Repin1 as regulator of adipocyte size was shown.Repin1 seems to be involved in the regulation of genes involved in adipogenesis.

  5. AP4 and geminin act as a repressor complex distinct from REST/NRSF to negatively regulate the expression of target genes in nonneuronal cells.

Mouse (Murine) Replication Initiator 1 (REPIN1) interaction partners

  1. Our findings indicate that Repin1 plays a role in insulin (show INS Proteins) sensitivity and lipid metabolism by regulating key genes of glucose and lipid metabolism.

  2. a potential role for Repin1 as regulator of adipocyte size was shown.Repin1 seems to be involved in the regulation of genes involved in adipogenesis.

REPIN1 Protein Profile

Protein Summary

Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication. Binds on 5'-ATT-3' reiterated sequences downstream of the origin of bidirectional replication (OBR) and a second, homologous ATT sequence of opposite orientation situated within the OBR zone. Facilitates DNA bending (By similarity).

Gene names and symbols associated with REPIN1

  • replication initiator 1 (REPIN1)
  • replication initiator 1 (Repin1)
  • AI425994 protein
  • Ap-4 protein
  • Ap4 protein
  • E430037F08Rik protein
  • REPIN1 protein
  • RIP60 protein
  • Zfp-464 protein
  • Zfp464 protein
  • ZNF464 protein

Protein level used designations for REPIN1

replication initiator 1 , replication initiator 1-like , 60 kDa origin-specific DNA-binding protein , 60 kDa replication initiation region protein , ATT-binding protein , DHFR oribeta-binding protein RIP60 , H_DJ0584D14.12 , replication initiation region protein (60kD) , zinc finger protein 464 (RIP60) , zinc finger protein AP4

GENE ID SPECIES
482792 Canis lupus familiaris
100460637 Pongo abelii
100585516 Nomascus leucogenys
100612359 Pan troglodytes
29803 Homo sapiens
511510 Bos taurus
58887 Mus musculus
445541 Rattus norvegicus
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