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anti-Rhotekin (RTKN) Antibodies

RTKN encodes a scaffold protein that interacts with GTP-bound Rho proteins. Additionally we are shipping Rhotekin Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RTKN 6242 Q9BST9
RTKN 20166 Q8C6B2
RTKN 297383 Q6V7V2
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Top anti-Rhotekin Antibodies at antibodies-online.com

Showing 10 out of 32 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RTKN Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RTKN Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated WB RTKN monoclonal antibody (M01), clone 2E5 Western Blot analysis of RTKN expression in A-431 on formalin-fixed paraffin-embedded human colon (antibody concentration 3 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of Rhotekin staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Rhotekin expression in HeLa (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Mouse Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$529.83
Details
Human Rabbit Un-conjugated WB Rhotekin antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated WB Rhotekin antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details

RTKN Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
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Mouse (Murine) ,


Rat (Rattus) ,


Top referenced anti-Rhotekin Antibodies

  1. Cow (Bovine) Polyclonal Rhotekin Primary Antibody for WB - ABIN2774136 : Sudo, Ito, Iwamoto, Morishita, Asano, Nagata: SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/SEPT11 and resistance to Rho/Rhotekin-signaling. in Human mutation 2007 (PubMed)

More Antibodies against Rhotekin Interaction Partners

Human Rhotekin (RTKN) interaction partners

  1. RTKN could affect the proliferation and metastasis of colon cancer by reducing expression of MCM2 (show MCM2 Antibodies)/3/5, CDK1 (show CDK1 Antibodies)/2 and PCNA (show PCNA Antibodies)

  2. suggest that interaction of S100A4 (show S100A4 Antibodies) and Rhotekin permits S100A4 (show S100A4 Antibodies) to complex with RhoA (show RHOA Antibodies) and switch Rho function from stress fiber formation to membrane ruffling to confer an invasive phenotypea

  3. Protein kinase D (show PRKD1 Antibodies) regulates RhoA (show RHOA Antibodies) activity via phosphorylation rhotekin at Ser (show SIGLEC1 Antibodies)-435.

  4. Rho/RTKN-mediated NF-kappaB (show NFKB1 Antibodies) activation leading to cell survival may play a key role in gastric tumorigenesis.

  5. These results suggest that the RTKN gene is involved in bladder carcinogenesis and progression in bladder carcinoma, indicating that RTKN gene could be a molecular target in cancer therapy.

  6. Lin-7B (show LIN7B Antibodies) is a binding partner for Rhotekin in the human brain cDNA library

  7. SEPT9 (show SEPT9 Antibodies) sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4 (show SEPT4 Antibodies)/SEPT11 (show SEPT11 Antibodies) and resistance to Rho/Rhotekin-signaling

  8. Rhotekin forms a complex with vinexin (show Sorbs3 Antibodies) and may play a role at focal adhesions.

  9. Loss of miR (show MLXIP Antibodies)-145 may provide a selective growth advantage for MCF-7 by targeting RTKN.

Mouse (Murine) Rhotekin (RTKN) interaction partners

  1. these findings suggest that cGK (show PRKG1 Antibodies)-Ialpha interacts with and phosphorylates rhotekin, thereby contributing to neurite outgrowth regulation.

Rhotekin (RTKN) Antigen Profile

Protein Summary

This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with anti-Rhotekin (RTKN) Antibodies

  • rhotekin (RTKN) antibody
  • rhotekin (rtkn) antibody
  • rhotekin (Rtkn) antibody
  • RTKN antibody

Protein level used designations for anti-Rhotekin (RTKN) Antibodies

rhotekin , rhotekin-like

GENE ID SPECIES
459334 Pan troglodytes
100053888 Equus caballus
100124981 Xenopus (Silurana) tropicalis
100349385 Oryctolagus cuniculus
100400941 Callithrix jacchus
100455723 Pongo abelii
100474465 Ailuropoda melanoleuca
100519086 Sus scrofa
6242 Homo sapiens
20166 Mus musculus
297383 Rattus norvegicus
475788 Canis lupus familiaris
539691 Bos taurus
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