Ring Finger and FYVE-Like Domain Containing 1 Proteins (RFFL)

Has E3 ubiquitin protein ligase activity. Additionally we are shipping RFFL Antibodies (65) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RFFL 67338 Q6ZQM0
RFFL 117584 Q8WZ73
RFFL 282844 Q8CIN9
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Top RFFL Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,990.17
Details

RFFL Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,
Rat (Rattus)

More Proteins for Ring Finger and FYVE-Like Domain Containing 1 (RFFL) Interaction Partners

Mouse (Murine) Ring Finger and FYVE-Like Domain Containing 1 (RFFL) interaction partners

  1. EGF (show EGF Proteins), which signals through CRAF (show RAF1 Proteins), and an activated BRAF (show BRAF Proteins) mutant also activate PKC and stimulate cell migration through up-regulating RFFL expression.

  2. Data show that the the amino-terminal domain of rififylin is critical for its recruitment to recycling endocytic membranes and for the inhibition of recycling.

  3. CARP2 (show CA11 Proteins) [Rififylin] deficiency does not alter induction of NF-kappaB (show NFKB1 Proteins) by TNFalpha (show TNF Proteins).

Human Ring Finger and FYVE-Like Domain Containing 1 (RFFL) interaction partners

  1. it is interesting to note that a human lncRNA does exist within the 5'-UTR intronic region of the human RFFL gene . Given the rat data, our study may serve as a translational foundation for considering this human lncRNA as a candidate regulator for cardiovascular diseases.

  2. EGF (show EGF Proteins), which signals through CRAF (show RAF1 Proteins), and an activated BRAF (show BRAF Proteins) mutant also activate PKC (show PRRT2 Proteins) and stimulate cell migration through up-regulating RFFL expression.

  3. data indicate AE induces caspase-8 (show CASP8 Proteins)-mediated activation of mitochondrial death pathways by decreasing the stability of CARP (show CA8 Proteins) mRNAs in a p53 (show TP53 Proteins)-independent manner.

  4. CARPs together with MDM2 (show MDM2 Proteins) enhance p53 (show TP53 Proteins) degradation, thereby inhibiting p53 (show TP53 Proteins)-mediated cell death.

  5. acts at the level of endocytic vesicles to limit the intensity of TNF (show TNF Proteins)-induced NF-kappaB (show NFKB1 Proteins) activation by the regulated elimination of a necessary signaling component within the receptor complex

RFFL Protein Profile

Protein Summary

Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates (By similarity). Overexpression slows protein traffic through recycling endosomes.

Gene names and symbols associated with RFFL

  • ring finger and FYVE-like domain containing E3 ubiquitin protein ligase (RFFL)
  • ring finger and FYVE-like domain containing 1 (rffl)
  • ring finger and FYVE-like domain containing 1 (RFFL)
  • ring finger and FYVE-like domain containing 1 (Rffl)
  • ring finger and FYVE like domain containing protein (Rffl)
  • ring finger and FYVE-like domain containing E3 ubiquitin protein ligase (Rffl)
  • 1700051E09Rik protein
  • 4930516L10Rik protein
  • BG080975 protein
  • CARP-2 protein
  • CARP2 protein
  • FRING protein
  • MGC84042 protein
  • Rffl protein
  • RIFIFYLIN protein
  • RNF34L protein
  • RNF189 protein

Protein level used designations for RFFL

E3 ubiquitin-protein ligase rififylin , ring finger and FYVE-like domain containing 1 , rififylin , e3 ubiquitin-protein ligase rififylin-like , RING finger and FYVE-like domain-containing protein 1 , fring , FYVE-RING finger protein SAKURA , RING finger protein 189 , caspase regulator CARP2 , caspases-8 and -10-associated RING finger protein 2 , FYVE-RING finger protein Sakura , RING finger protein SAKURA , ring finger and FYVE like domain containing protein

GENE ID SPECIES
417529 Gallus gallus
447349 Xenopus laevis
454582 Pan troglodytes
491144 Canis lupus familiaris
530263 Bos taurus
100058179 Equus caballus
100115488 Nasonia vitripennis
100464760 Ailuropoda melanoleuca
100604408 Nomascus leucogenys
67338 Mus musculus
117584 Homo sapiens
282844 Rattus norvegicus
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