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The protein encoded by S100A6 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. Additionally we are shipping S100A6 Kits (67) and S100A6 Proteins (37) and many more products for this protein.
Showing 10 out of 164 products:
Human Monoclonal S100A6 Primary Antibody for IF, WB - ABIN396682
van Dieck, Lum, Teufel, Fersht: S100 proteins interact with the N-terminal domain of MDM2. in FEBS letters 2010
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Human Monoclonal S100A6 Primary Antibody for WB - ABIN396706
Wei, Hoover, Ross, Zhou, Meani, Edwards, Spehalski, Risinger, Alvord, Quiñones, Belluco, Martella, Campagnutta, Ravaggi, Dai, Goldsmith, Woolard, Pecorelli, Liotta, Petricoin, Simpson: Serum S100A6 concentration predicts peritoneal tumor burden in mice with epithelial ovarian cancer and is associated with advanced stage in patients. in PLoS ONE 2009
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Human Monoclonal S100A6 Primary Antibody for ELISA, WB - ABIN562772
Di Tomaso, Mazzoleni, Wang, Sovena, Clavenna, Franzin, Mortini, Ferrone, Doglioni, Marincola, Galli, Parmiani, Maccalli: Immunobiological characterization of cancer stem cells isolated from glioblastoma patients. in Clinical cancer research : an official journal of the American Association for Cancer Research 2010
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Human Polyclonal S100A6 Primary Antibody for FACS, WB - ABIN391522
van Dieck, Fernandez-Fernandez, Veprintsev, Fersht: Modulation of the oligomerization state of p53 by differential binding of proteins of the S100 family to p53 monomers and tetramers. in The Journal of biological chemistry 2009
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Cat (Feline) Polyclonal S100A6 Primary Antibody for IHC (p) - ABIN181371
Schäfer, Heizmann: The S100 family of EF-hand calcium-binding proteins: functions and pathology. in Trends in biochemical sciences 1996
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Human Monoclonal S100A6 Primary Antibody for IHC, ELISA - ABIN969470
Hwang, Lee, Kim, Li, Jin, Rhee, Kim, Lim: Calcyclin, a Ca2+ ion-binding protein, contributes to the anabolic effects of simvastatin on bone. in The Journal of biological chemistry 2004
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Human Monoclonal S100A6 Primary Antibody for IF, IHC (p) - ABIN562771
Li, Riau, Setiawan, Mehta, Ti, Tong, Tan, Beuerman: S100A expression in normal corneal-limbal epithelial cells and ocular surface squamous cell carcinoma tissue. in Molecular vision 2011
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Human Polyclonal S100A6 Primary Antibody for ICC, IF - ABIN4351707
Damaghi, Tafreshi, Lloyd, Sprung, Estrella, Wojtkowiak, Morse, Koomen, Bui, Gatenby, Gillies: Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane. in Nature communications 2015
The S100A6 interacts with FOR20 (show FOPNL Antibodies) and related centrosomal proteins through a conserved N-terminal domain, suggesting a novel Ca(2 (show CA2 Antibodies)+)-dependent regulation of centrosomal function.
REVIEW: summary of novel discoveries concerning S100A6 targets, its involvement in cellular signaling pathways, and presence in stem/progenitor cells, extracellular matrix and body fluids of diseased patients
Results showed that S100A6 was markedly up-regulated in nasopharyngeal carcinoma (NPC (show NPC1 Antibodies)) tissues and cell lines and, may promote NPC (show NPC1 Antibodies) development via the activation of p38/MAPK (show MAPK14 Antibodies) signaling pathways.
As an intracellular protein (show CKAP2 Antibodies), S100A6 has been implicated in the regulation of several cellular functions, such as proliferation, apoptosis, the cytoskeleton dynamics, and the cellular response to different stress factors. S100A6 can be secreted/released by certain cell types which points to extracellular effects of the protein. [review]
suppression of S100A6 expression with RNAi significantly decreased the expression levels of beta-catenin (show CTNNB1 Antibodies), inhibited the growth and migration of eutopic endometrial stromal cells, and promoted their apoptosis.
Study reports the crystallographic structure of an S100-bound full-length RAGE (show AGER Antibodies) ectodomain. The structure reveals a unique dimeric conformation of RAGE (show AGER Antibodies), which appears suited for signal transduction, and shows that the S100A6 protein adopts a non-canonical homodimeric arrangement.
STAT1 (show STAT1 Antibodies) suppression by S100A6 may represent a promising therapeutic target to facilitate reendothelialization in damaged vessels.
Our results indicate that serum levels of S100A2 (show S100A2 Antibodies) and S100A6 are significantly elevated in early stage non-small cell lung cancer
findings strongly suggest that S100A6 may promote OS cell proliferation and OS tumor growth at least in part by facilitating cell cycle progression, preventing apoptosis, and inhibiting osteogenic differentiation
S100A6 induces EMT (show ITK Antibodies) and promotes cell migration and invasion in a beta (show SUCLA2 Antibodies)-catenin (show CTNNB1 Antibodies)-dependent manner.
S100A6 is upregulated during PRRSV infection; there is a putative NF-kappaB (show NFKB1 Antibodies) binding site in the core promoter region
our data provide the first evidence that S100A6 is a specific marker of neural stem cells and astrocyte precursors
new insight into the interaction between S100 proteins and CacyBP/SIP (show CACYBP Antibodies)
the S100A6 protein is involved in multiple aspects of fibroblast physiology and that its presence ensures normal fibroblast proliferation and function
S100A6 concentration predicts peritoneal tumor burden in mice with epithelial ovarian cancer and is associated with advanced stage in patients
calcyclin has a role as an accessory protein involved in the cation-sensing pathway in osteoblasts
Calcyclin is one of the candidate proteins that plays a role in osteoblastogenesis in response to simvastatin, although the precise functions of calcyclin in osteoblast remain to be verified.
calcyclin gene expression was analyzed at three different stages in differentiating MyoD (show MYOD1 Antibodies)(-)C2C12 myoblasts
Annexin XI (show ANXA11 Antibodies) and calcyclin colocalize in proliferating cells of the embryonic mouse testis
S100A2 (show S100A2 Antibodies) and S100A6 interact with another TPR (show GRID2 Antibodies) protein Tom70 (show TOMM70A Antibodies) and regulate the Tom70 (show TOMM70A Antibodies)-ligand interaction in vitro
enhancement of S100A6 expression plays an important role in MLL-AF4-associated leukemogenesis
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
S100 calcium binding protein A6
, MLN 4
, S100 calcium-binding protein A6 (calcyclin)
, growth factor-inducible protein 2A9
, prolactin receptor-associated protein
, protein S100-A6
, S100 calcium-binding protein A6
, calcium binding protein A6 (calcyclin)
, lung 10 kDa protein