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May have a role in a signaling pathway. Additionally we are shipping SASH1 Antibodies (65) and and many more products for this protein.
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Two SNPs were significantly associated with rotator cuff tearing, residing in SAP30BP (show SAP30BP Proteins) on chromosome 17 and SASH1 on chromosome 6.
SASH1 expression is increased in atherosclerotic carotids in smokers and its silencing affects endothelial angiogenic functions
SASH1 expression strongly correlated with glioma grades, showing higher expression at a lower grade.
Data suggest that SASH1 (SAM and SH3 domain-containing protein 1) should be added to the list of genes responsible for autosomal-dominant and -recessive genodermatosis.
SASH1 Is Involved in an Autosomal Dominant Lentiginous Phenotype.
Propose that increase of DNA methylation (show HELLS Proteins) level in the promoter region of gene SASH1, particularly CpG_26.27 or CpG_54.55 sites, possibly repressed SASH1 expression in breast cancer.
The SASH1 gene is blocked cyclin B1 (show CCNB1 Proteins)-Cdc2 (show CDK1 Proteins) binding, either directly or indirectly, leading to G2/M arrest.
SASH1 regulates IQGAP1-E-Cadherin (show CDH1 Proteins) signalling and crosstalking between GPCR (show NMUR1 Proteins) signalling, calmodulin (show CALM1 Proteins) signalling for the modulation of melanocytes invasion.
Overexpression of SASH1 might be associated with the inhibition of growth, proliferation, and invasion osteosarcoma cells.
Loss of SASH1 is associated with glioma.
SASH1 acts to assemble a signaling complex downstream of TLR4 (show TLR4 Proteins) to activate early endothelial responses to receptor activation.
Not expressed in the investigated haematopoietic cell lines, while transcripts were found in whole splenic B-cells from both wild type and Btk (show BTK Proteins)-defective mice.
May have a role in a signaling pathway. Could act as a tumor suppressor.
SAM and SH3 domain containing 1
, SAM and SH3 domain-containing protein 1-like
, SAM and SH3 domain-containing protein 1
, proline-glutamate repeat-containing protein
, putative adapter and scaffold protein 1