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anti-SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) Antibodies

Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. Additionally we are shipping SCO1 Cytochrome C Oxidase Assembly Protein Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SCO1 16590 P05532
SCO1 6341 O75880
SCO1 497930  
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Top anti-SCO1 Cytochrome C Oxidase Assembly Protein Antibodies at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SCO1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of SCO1 in human brain tissue with this product at 2.5 μg/ml. Western blot analysis of SCO1 in human brain tissue lysate with this product at (A) 0.5 and (B) 1 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with SCO1 antibody ABIN214471 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Heart (formalin-fixed, paraffin-embedded) stained with SCO1 antibody ABIN214471 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 15 to 19 Days
$455.07
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of SCO1 expression in transfected 293T cell line by SCO1 MaxPab polyclonal antibody.Lane 1: SCO1 transfected lysate(33.11 KDa).Lane 2: Non-transfected lysate. SCO1 MaxPab polyclonal antibody. Western Blot analysis of SCO1 expression in human liver. 50 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated WB SCO1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details

SCO1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


Human
,

Rat (Rattus)


Top referenced anti-SCO1 Cytochrome C Oxidase Assembly Protein Antibodies

  1. Human Polyclonal SCO1 Primary Antibody for EIA, IHC (p) - ABIN500686 : Horng, Leary, Cobine, Young, George, Shoubridge, Winge: Human Sco1 and Sco2 function as copper-binding proteins. in The Journal of biological chemistry 2005 (PubMed)
    Show all 4 references for ABIN500686

  2. Human Polyclonal SCO1 Primary Antibody for IHC, ELISA - ABIN1003126 : Glerum, Shtanko, Tzagoloff: SCO1 and SCO2 act as high copy suppressors of a mitochondrial copper recruitment defect in Saccharomyces cerevisiae. in The Journal of biological chemistry 1996 (PubMed)
    Show all 4 references for ABIN1003126

  3. Human Polyclonal SCO1 Primary Antibody for WB - ABIN2786787 : Banci, Bertini, Ciofi-Baffoni, Hadjiloi, Martinelli, Palumaa: Mitochondrial copper(I) transfer from Cox17 to Sco1 is coupled to electron transfer. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

More Antibodies against SCO1 Cytochrome C Oxidase Assembly Protein Interaction Partners

Mouse (Murine) SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) interaction partners

  1. IMC-G4 cells had an additional novel c-kit (show KIT Antibodies) gene mutation of KIT-Tyr421Cys which is considered to induce neoplastic transformation of mouse mast cells

  2. gene deficiency does not play a role in the pathogenesis of lupus in B6lpr/lpr (show FAS Antibodies) mice.

  3. suggests FGF-9 has the potential to attenuate vascular cell apoptosis, activate c-Kit (show KIT Antibodies) progenitor cells, and enhance angiogenesis and neovascularization in C57BL/6 and db/db (show LEPR Antibodies) mice leading to improved cardiac function.

  4. Bone marrow-derived CD117+ hematopoietic progenitor cells differentiate into thymic dendritic cells in the fetal thymus organ culture system in the presence of Flt3L (show FLT3LG Antibodies).

  5. C-kit (show KIT Antibodies) signaling has a role in proliferation and invasion of colorectal mucinous adenocarcinoma

  6. TAK1 (show NR2C2 Antibodies) and IKK2 (show IKBKB Antibodies) are novel mediators of SCF (show KITLG Antibodies)-induced signaling and potential targets for c-Kit (show KIT Antibodies)-driven diseases.

  7. Findings indicate that CD45 antigen (show PTPRC Antibodies)(+) and c-Kit (show KIT Antibodies) protein(+) hematopoietic cells were more abundant in muscle than in bone marrow between embryonic 14.5 and 17.5 days.

  8. c-kit (show KIT Antibodies)(+) cells in the murine heart are endothelial cells and not cardiac stem cells.

  9. As SALL4A (show SALL4 Antibodies) is known to impair ZBTB16 (show ZBTB16 Antibodies)-mediated Kit repression [14], our study provides novel insights into the molecular mechanism by which ATRA could control KIT expression, and thereby the differentiation of Aal into A1 spermatogonia in vivo.

  10. Data show that PI3 kinase (show PIK3CA Antibodies) is an attractive therapeutic target in malignancies induced by proto-oncogene (show RAB1A Antibodies) protein c (show PROC Antibodies)-Kit (show KIT Antibodies) mutations.

Human SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) interaction partners

  1. Results find that COA6 associates with COX2 (show COX2 Antibodies) and is crucial for its maturation and complex IV biogenesis. Also, COA6 interacts with the copper chaperone SCO1 which indicates that COA6 is intrinsically involved in the copper delivery process for COX2 (show COX2 Antibodies).

  2. Sco1 is a metallochaperone that selectively transfers Cu(I) ions based on loop recognition, whereas Sco2 is a copper-dependent thiol reductase of the cysteine ligands in the oxidase.

  3. COX20 cooperates with SCO1 and SCO2 (show SCO2 Antibodies) to mature COX2 (show COX2 Antibodies) and promote the assembly of cytochrome c (show CYCS Antibodies) oxidase.

  4. COX19 (show COX19 Antibodies) is necessary for the transduction of a SCO1-dependent mitochondrial redox signal that regulates ATP7A (show ATP7A Antibodies)-mediated cellular copper efflux.

  5. Results describe the tissue distribution of SCO1 and SCO2 in mouse and human tissues.

  6. SCO1 facilitates the transfer of copper from SCO2 (show SCO2 Antibodies) to the CuA site at an early stage of COX (show COX8A Antibodies) assembly in mitochondria.

  7. data suggest that both Cu(I) and Cu(II) binding are critical for normal Sco (show SNAI1 Antibodies) function.

  8. Cox17-mediated copper metallation of Sco1, as well as the subsequent failure of Cu(A) site maturation, is the basis for the inefficient assembly of the cytochrome c oxidase complex in SCO1 patients

  9. Sco1 has evolved to bind a metal atom via the di-Cys (show DNAJC5 Antibodies) motif to act as a copper chaperone, the oxidized form of the nickel-bound protein suggests that it may also maintain the thioredoxin (show TXN Antibodies) function.

  10. These results suggest a mitochondrial pathway for the regulation of cellular copper content that involves signaling through SCO1 and SCO2, perhaps by their thiol redox or metal-binding state.

SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) Antigen Profile

Protein Summary

Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of cytochrome c oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog to the yeast SCO1 gene.

Gene names and symbols associated with SCO1

  • kit oncogene (Kit) antibody
  • SCO cytochrome oxidase deficient homolog 1 (yeast) (SCO1) antibody
  • SCO1 cytochrome c oxidase assembly protein (SCO1) antibody
  • SCO1 cytochrome c oxidase assembly protein (Sco1) antibody
  • Bs antibody
  • c-KIT antibody
  • CD117 antibody
  • Fdc antibody
  • Gsfsco1 antibody
  • Gsfsco5 antibody
  • Gsfsow3 antibody
  • RGD1559538 antibody
  • SCO1 antibody
  • SCO5 antibody
  • SCOD1 antibody
  • SOW3 antibody
  • Ssm antibody
  • Tr-kit antibody
  • W antibody

Protein level used designations for SCO1

Dominant white spotting , SCFR , Steel Factor Receptor , belly-spot , c-kit proto-oncogene protein , dominant spotting , mast/stem cell growth factor receptor Kit , proto-oncogene c-Kit , proto-oncogene tyrosine-protein kinase Kit , spotted sterile male , tyrosine-protein kinase Kit , protein SCO1 homolog, mitochondrial , SCO cytochrome oxidase deficient homolog 1

GENE ID SPECIES
16590 Mus musculus
508586 Bos taurus
6341 Homo sapiens
497930 Rattus norvegicus
Selected quality suppliers for anti-SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) Antibodies
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