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SCO1 Products

(SCO1 Cytochrome C Oxidase Assembly Protein (SCO1))

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Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of cytochrome c oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog to the yeast SCO1 gene. [provided by RefSeq, Jul 2008].

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Featured SCO1 Categories

SCO1 Antibodies

High quality antibodies with extensive validation data.

SCO1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SCO1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN6147455
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN520031
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6244221
Quantity 50 μL
Datasheet Datasheet

Recommended SCO1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6235104
Quantity 96 tests
Datasheet Datasheet

Recommended SCO1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124990
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1784455
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319296
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our SCO1 products

Rolland, Motori, Memar, Hench, Frank, Winklhofer, Conradt: "Impaired complex IV activity in response to loss of LRPPRC function can be compensated by mitochondrial hyperfusion." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 32, pp. E2967-76, (2013) (PubMed).

Banci, Bertini, Ciofi-Baffoni, Leontari, Martinelli, Palumaa, Sillard, Wang: "Human Sco1 functional studies and pathological implications of the P174L mutant." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 1, pp. 15-20, (2007) (PubMed).

Horng, Leary, Cobine, Young, George, Shoubridge, Winge: "Human Sco1 and Sco2 function as copper-binding proteins." in: The Journal of biological chemistry, Vol. 280, Issue 40, pp. 34113-22, (2005) (PubMed).

Valnot, Osmond, Gigarel, Mehaye, Amiel, Cormier-Daire, Munnich, Bonnefont, Rustin, Rötig: "Mutations of the SCO1 gene in mitochondrial cytochrome c oxidase deficiency with neonatal-onset hepatic failure and encephalopathy." in: American journal of human genetics, Vol. 67, Issue 5, pp. 1104-9, (2000) (PubMed).

Glerum, Shtanko, Tzagoloff: "SCO1 and SCO2 act as high copy suppressors of a mitochondrial copper recruitment defect in Saccharomyces cerevisiae." in: The Journal of biological chemistry, Vol. 271, Issue 34, pp. 20531-5, (1996) (PubMed).

Synonyms and alternative names related to SCO1

SCO1, cytochrome c oxidase assembly protein (SCO1), SCO1 cytochrome c oxidase assembly protein (Sco1), SCO1 cytochrome c oxidase assembly protein (sco1), 2610001C07Rik, D11Bwg1310e, RGD1559538, SCO1, SCOD1

Protein level used designations for SCO1

  • SCO cytochrome oxidase deficient homolog 1
  • protein SCO1 homolog, mitochondrial
  • SCO cytochrome oxidase deficient homolog 1 (yeast)
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