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The protein encoded by SIX1 is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. Additionally we are shipping SIX Homeobox 1 Proteins (6) and many more products for this protein.
Showing 10 out of 32 products:
Human Polyclonal SIX1 Primary Antibody for ICC, IF - ABIN4353939
Wan, Miao, Quraishi, Kennedy, Creek, Pirisi: Gene expression changes during HPV-mediated carcinogenesis: a comparison between an in vitro cell model and cervical cancer. in International journal of cancer 2008
Show all 15 references for ABIN4353939
Cow (Bovine) Polyclonal SIX1 Primary Antibody for WB - ABIN2779599
Lee, Kim, Ryu, Lee, Yang, Jeong, Kim, Lee, Kim, Hajjar, Park: Transcription coactivator Eya2 is a critical regulator of physiological hypertrophy. in Journal of molecular and cellular cardiology 2012
Show all 2 references for ABIN2779599
Human Polyclonal SIX1 Primary Antibody for ELISA, WB - ABIN1451301
Boucher, Carey, Edwards, Siciliano, Johnson: Cloning of the human SIX1 gene and its assignment to chromosome 14. in Genomics 1996
Our findings imply that SIX1 may play a role as an important regulator to orchestrate the dynamic of uterine endometrium in response to estrogen level during the estrous cycle.
Activation of Six1 Expression in Vertebrate Sensory Neurons.
Six1 knockdown caused a fast-to-slow shift in myosin heavy chain isoform
Results suggest that the increase of SIX1 expression could promote tumorigenesis, progression and invasive growth of cervical cancer by promoting DNA replication.
Fast myosin heavy chain (show MYH8 Antibodies) (MYH (show MUTYH Antibodies)) genes and linc-MYH (show MUTYH Antibodies) share a common enhancer, located in the fast MYH (show MUTYH Antibodies) gene locus and regulated by Six1 homeoproteins
The results indicated the critical role of Six1 in transition of Rohon-Beard cells to dorsal root ganglia (DRG) neurons during Xenopus development and establishment of exclusive DRG system of mice.
Six1 is required for the proper chromatin structure at the Core Enhancer Region, as well as for MyoD (show MYOD1 Antibodies) binding at its own enhancer.
Results indicated that sine oculis homeobox (show PRRX1 Antibodies) 1 (Six1) overexpression could significantly promote the expression of fast-type muscle genes Atp2a1 (show ATP2A1 Antibodies), Srl (show SRL Antibodies), and Mylpf (show MYLPF Antibodies).
These findings uncover novel functions for Six1-Eya1 (show EYA1 Antibodies)-SHH (show SHH Antibodies) pathway during the saccular phase of lung morphogenesis.
the transcription factors Six1 and Six4 (show SIX4 Antibodies) are required for male gonadal differentiation.
Data show that the protein domain interfaces may represent therapeutic targets in homeo domain protein SIX1-positive Hodgkin lymphoma (HL) subsets.
Data show that both Ezrin (show EZR Antibodies) and SIX1 proteins are highly expressed in alpha fetoprotein (show AFP Antibodies)-negative hepatocellular carcinoma (HCC (show FAM126A Antibodies)) and significantly related with the TNM (show ODZ1 Antibodies) stage.
Single nucleotide polymorphism in SIX1 gene is associated with primary open angle glaucoma.
High expression of SIX1 is an independent prognostic marker in colorectal cancer.
Three causative genes for BOR (show EYA1 Antibodies) syndrome have been reported thus far: EYA1 (show EYA1 Antibodies), SIX1, and SIX5, but the causative genes for approximately half of all BOR (show EYA1 Antibodies) patients remain unknown.[review]
SIX1 and EYA are often co-overexpressed in tumors, and the SIX1-EYA2 (show EYA2 Antibodies) interaction has been shown to be critical for metastasis in a breast cancer model.
Six1 plays an important role in the TIC (show ARNTL Antibodies) population in luminal breast cancers and induces a TIC (show ARNTL Antibodies) phenotype by enhancing both TGF-beta (show TGFB1 Antibodies) and ERK (show EPHB2 Antibodies) signaling.
SIX1 plays an important role in the progression ofhepatocellular carcinoma
in tumors with DGCR8 (show DGCR8 Antibodies) E518K and DROSHA (show DROSHA Antibodies) exon 29 (miRNAPG-HS) mutations ... greater prevalence of tumors with blastemal predominant histology in patients with miRNAPG-HS and/or SIX1/2 Q177R mutations
Recurrent mutations included a hotspot mutation (Q177R) in the homeo-domain of SIX1 and SIX2 (show SIX2 Antibodies) in tumors with high proliferative potential (18.1% of blastemal cases); mutations in the DROSHA (show DROSHA Antibodies)/DGCR8 (show DGCR8 Antibodies) microprocessor genes
The HD domain is important for the nuclear localization of porcine Six1 protein.
Microarray identification of novel genes downstream of Six1, a critical factor in cranial placode, somite, and kidney development.
Eya1 (show EYA1 Antibodies) and Six1 are required for both the regulation of placodal neuronal progenitor proliferation, through their effects on SoxB1 expression, and subsequent neuronal differentiation.
The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3).
homeobox protein SIX1
, sine oculis homeobox homolog 1
, sine oculis-related homeobox 1 homolog
, Sine oculis homeobox homolog 1
, homeobox protein six1