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SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. Additionally we are shipping SNF8, ESCRT-II Complex Subunit, Homolog (S. Cerevisiae) Antibodies (60) and SNF8, ESCRT-II Complex Subunit, Homolog (S. Cerevisiae) Kits (3) and many more products for this protein.
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Taken together, these data suggest an active role for ESCRT-II (show VPS28 Proteins) and CHMP6 (show CHMP6 Proteins) in ESCRT-mediated abscission
Modulating SNF8 expression levels alters the TRPC6 (show TRPC6 Proteins) channel current and can modulate activation of NFAT (show NFATC1 Proteins)-mediated transcription downstream of gain-of-function mutant TRPC6 (show TRPC6 Proteins).
mammalian ESCRTII (show VPS28 Proteins) is made up of hVps25p, hVps22p, and hVps36p and may be redundant, cargo-specific, or not required for protein sorting at the multivesicular body
there are probably multiple pathways for protein sorting/multivesicular body vesicle formation in human cells and that human immunodeficiency virus type 1 does not utilize an ESCRT-II (show VPS28 Proteins)-dependent pathway to leave the cell
Vps22 (show CHMP2B Proteins) has an important role in ligand-induced EGFR (show EGFR Proteins) and CXCR4 (show CXCR4 Proteins) turnover; termination of EGF (show EGF Proteins) signaling occurs prior to ESCRT-II (show VPS28 Proteins) engagement
SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL\; MIM 600284) (Slagsvold et al., 2005
EAP30 subunit of ELL complex
, ESCRT-II complex subunit VPS22
, SNF8, ESCRT-II complex subunit, homolog
, vacuolar-sorting protein SNF8
, eap30 subunit of ell complex
, SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
, vacuolar-sorting protein snf8
, ELL-associated protein of 30 kDa
, vacuolar sorting snf8 ELL associated of 30kDa