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SRY (Sex Determining Region Y)-Box 12 Proteins (SOX12)

Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Additionally we are shipping SOX12 Antibodies (51) and SOX12 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SOX12 6666 O15370
Rat SOX12 SOX12 689988  
SOX12 20667 Q04890
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Top SOX12 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,623.50
Details

SOX12 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for SRY (Sex Determining Region Y)-Box 12 (SOX12) Interaction Partners

Human SRY (Sex Determining Region Y)-Box 12 (SOX12) interaction partners

  1. Up-regulated Sox12 induced by FoxQ1 (show FOXQ1 Proteins) promotes hepatocellular carcinoma invasion and metastasis by transactivating Twist1 (show TWIST1 Proteins) and FGFBP1 (show FGFBP1 Proteins) expression.

  2. This genome-wide screen has identified two novel metastatic suppressors: TMED3 (show TMED3 Proteins) and SOX12, the knockdown of which increases metastatic growth after direct seeding.

  3. SOX12 and NRSN2 (show NRSN2 Proteins) were identified as candidate genes that may be involved in the developmental defects in 20p13 microdeletion.

Xenopus laevis SRY (Sex Determining Region Y)-Box 12 (SOX12) interaction partners

Mouse (Murine) SRY (Sex Determining Region Y)-Box 12 (SOX12) interaction partners

  1. SOXC proteins act cell- and non-cell-autonomously in perichondrocytes and chondrocytes to establish noncanonical WNT (show WNT2 Proteins) signaling crosstalk essential for growth plate induction and control

  2. Study show that the survival of neural and mesenchymal progenitor cells critically relies on the redundantly acting SoxC transcription factors Sox4, Sox11 (show SOX11 Proteins) and Sox12.

  3. Sox4 and Sox11 (show SOX11 Proteins) function redundantly with Sox12 and can compensate its loss during mouse development.

SOX12 Protein Profile

Protein Summary

Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types.

Gene names and symbols associated with SOX12

  • SRY (sex determining region Y)-box 12 (SOX12)
  • SRY (sex determining region Y)-box 12 (Sox12)
  • SRY (sex determining region Y)-box 12 (sox12)
  • SRY-box containing gene 12 (Sox12)
  • 2010205A02Rik protein
  • sox-k1 protein
  • sox-k1-a protein
  • SOX22 protein
  • sox33 protein
  • xSox-33 protein
  • xSox-K1 protein
  • xSox33 protein

Protein level used designations for SOX12

SOX-22 protein , SRY-related HMG-box gene 22 , transcription factor SOX-12 , SRY-box containing gene 12 , Transcription factor Sox-33 , transcription factor Sox-12

GENE ID SPECIES
6666 Homo sapiens
485820 Canis lupus familiaris
689988 Rattus norvegicus
373574 Xenopus laevis
20667 Mus musculus
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