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SUMO1 Activating Enzyme Subunit 2 (UBA2) ELISA Kits

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. Additionally we are shipping SUMO1 Activating Enzyme Subunit 2 Antibodies (71) and SUMO1 Activating Enzyme Subunit 2 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
UBA2 10054 Q9UBT2
Anti-Mouse UBA2 UBA2 50995 Q9Z1F9
Anti-Rat UBA2 UBA2 308508  
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Top SUMO1 Activating Enzyme Subunit 2 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 2 to 3 Days
$380.00
Details

More ELISA Kits for SUMO1 Activating Enzyme Subunit 2 Interaction Partners

Human SUMO1 Activating Enzyme Subunit 2 (UBA2) interaction partners

  1. Here, we show that hHR23A utilizes both the UBA2 and XPCB domains to form a stable complex with Vpr, linking Vpr directly to cellular DNA repair pathways and their probable exploitation by the virus.

  2. Data indicate the role of anti-SUMO activating enzyme SAE1 (show SAE1 ELISA Kits) and SAE2 (show RBBP8 ELISA Kits) antibody as marker of dermatomyositis.

  3. Data show that the SAE2 (show RBBP8 ELISA Kits) subunit of the small ubiquitin-like modifier (SUMO (show SUMO1 ELISA Kits)) E1 is autoSUMOylated at residue Lys (show LYZ ELISA Kits)-236, and SUMOylation was catalyzed by Ubc9 (show UBE2I ELISA Kits) at several additional Lys (show LYZ ELISA Kits) residues surrounding the catalytic Cys (show DNAJC5 ELISA Kits)-173 of SAE2 (show RBBP8 ELISA Kits).

  4. loss of SAE1 (show SAE1 ELISA Kits)/2 activity drives synthetic lethality with Myc (show MYC ELISA Kits); inactivation of SAE2 (show RBBP8 ELISA Kits) leads to mitotic catastrophe and cell death upon Myc (show MYC ELISA Kits) hyperactivation; findings in Myc (show MYC ELISA Kits)-high breast cancers suggest low tumor SAE1 (show SAE1 ELISA Kits) and SAE2 (show RBBP8 ELISA Kits) correlates metastasis-free survival

  5. The mammalian E1 subunits can be imported separately, identify nuclear localization signals (NLSs) in Aos1 (show SAE1 ELISA Kits) and in Uba2, and demonstrate that their import is mediated by importin alpha (show KPNA4 ELISA Kits)/beta in vitro and in intact cells.

  6. structures of heterodimeric Sae1 (show SAE1 ELISA Kits)/Sae2 (show RBBP8 ELISA Kits)-Mg.ATP and Sae1 (show SAE1 ELISA Kits)/Sae2 (show RBBP8 ELISA Kits)-SUMO-1 (show SUMO1 ELISA Kits)-Mg.ATP complexes

  7. UBA2 stabilizes APOBEC3G by preventing ubiquitin chain elongation and proteasome-mediated proteolysis.

SUMO1 Activating Enzyme Subunit 2 (UBA2) Antigen Profile

Antigen Summary

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999

Gene names and symbols associated with UBA2

  • SUMO1 activating enzyme subunit 2 (MICPUN_63834) antibody
  • SUMO1 activating enzyme subunit 2 (MICPUCDRAFT_36729) antibody
  • SUMO-activating enzyme subunit 2 (SAE2) antibody
  • ubiquitin-like modifier activating enzyme 2 (UBA2) antibody
  • ubiquitin-like modifier activating enzyme 2 (Uba2) antibody
  • ubiquitin-like modifier activating enzyme 2 (uba2) antibody
  • AA986091 antibody
  • Arx antibody
  • ATSAE2 antibody
  • EMB2764 antibody
  • EMBRYO DEFECTIVE 2764 antibody
  • F3K23.23 antibody
  • F3K23_23 antibody
  • sae2 antibody
  • sae2-B antibody
  • sae2b antibody
  • SUMO-activating enzyme 2 antibody
  • UBA1 antibody
  • uba2-a antibody
  • uba2-b antibody
  • Ubl1a2 antibody
  • uble1b antibody
  • uble1b-B antibody
  • wu:fi17g06 antibody
  • zgc:66354 antibody

Protein level used designations for UBA2

SUMO1 activating enzyme subunit 2 , SUMO-1 activating enzyme subunit 2 , SUMO-activating enzyme subunit 2 , UBA2, ubiquitin-activating enzyme E1 homolog , anthracycline-associated resistance ARX , ubiquitin-like 1-activating enzyme E1B , Sumo-1 activating enzyme subunit 2 , ubiquitin-like 1 (sentrin) activating enzyme E1B , ubiquitin-like 1 (sentrin) activating enzyme subunit 2 , SUMO-activating enzyme subunit 2-A , SUMO-activating enzyme subunit 2-B , ubiquitin-like 1-activating enzyme E1B-A , ubiquitin-like 1-activating enzyme E1B-B , SUMO1 activating enzyme subunit 2b

GENE ID SPECIES
8248549 Micromonas sp. RCC299
9689179 Micromonas pusilla CCMP1545
816686 Arabidopsis thaliana
10054 Homo sapiens
50995 Mus musculus
308508 Rattus norvegicus
476490 Canis lupus familiaris
399235 Xenopus laevis
406672 Danio rerio
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