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anti-Secretogranin V (7B2 Protein) (SCG5) Antibodies

mouse homolog plays a role in the transport and activation of proprotein convertase-2 (PC2); may regulate hormone secretion. Additionally we are shipping Secretogranin V (7B2 Protein) Proteins (19) and Secretogranin V (7B2 Protein) Kits (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SCG5 20394 P12961
SCG5 25719 P27682
SCG5 6447 P05408
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Top anti-Secretogranin V (7B2 Protein) Antibodies at

Showing 10 out of 30 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: Secretogranin V Antibody [NBP1-90312] - Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in islet cells. 0.1 mL Log in to see 8 to 11 Days
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged SCG5 is 3 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.85 KDa) . 100 μg Log in to see 9 Days
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated WB Western blot analysis of Secretogranin 5 expression in HEK293T (A), MCF7 (B) whole cell lysates. 200 μL Log in to see 9 Days
Human Rabbit Un-conjugated IHC (p), WB Mouse spleen lysate probed with Rabbit Anti-Secretogranin-5 Polyclonal Antibody, Unconjugated (ABIN2559679) at 1:300 in 4˚C. Followed by conjugation to secondary antibody at 1:5000 for 90min at 37˚C. 100 μL Log in to see 3 to 7 Days
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 7 to 9 Days
Dog Rabbit Un-conjugated WB   50 μg Log in to see 7 to 9 Days
Bat Rabbit Un-conjugated WB   50 μg Log in to see 7 to 9 Days

SCG5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
Rat (Rattus)
Human , ,

Top referenced anti-Secretogranin V (7B2 Protein) Antibodies

  1. Human Polyclonal SCG5 Primary Antibody for IHC, IHC (p) - ABIN4352447 : Lindskog, Korsgren, Pontén, Eriksson, Johansson, Danielsson: Novel pancreatic beta cell-specific proteins: antibody-based proteomics for identification of new biomarker candidates. in Journal of proteomics 2012 (PubMed)

  2. Human Monoclonal SCG5 Primary Antibody for ELISA, WB - ABIN562854 : Lee, Ryu, Joo, Choi, Lee, Kim, Kim, Yoon: ?-Melanocyte-stimulating hormone inhibits tumor necrosis factor ?-stimulated MUC5AC expression in human nasal epithelial cells. in American journal of respiratory cell and molecular biology 2011 (PubMed)

More Antibodies against Secretogranin V (7B2 Protein) Interaction Partners

Mouse (Murine) Secretogranin V (7B2 Protein) (SCG5) interaction partners

  1. Dynamic modulation of prohormone convertase 2 (PC2 (show PCSK2 Antibodies))-mediated precursor processing by 7B2 protein has a preferential effect on glucagon (show GCG Antibodies) synthesis

  2. 7B2-related peptides modulate regulated secretion of ACTH (show POMC Antibodies) in neuroendocrine cells.

  3. 7B2 nulls exhibit a multisystem disorder of vital organs, most notably the liver, in which massive steatosis and necrosis are observed. Metabolic derangements in glucose metabolism result in glycogen (show GYS1 Antibodies) and fat deposition in liver

  4. 7B2 has a role in endoproteolytic processing in mouse brain

  5. data indicate that null prohormone convertase 2 (show PCSK2 Antibodies) and 7B2 protein are not phenotypically equivalent in pituitary proopiomelanocortin (POMC (show POMC Antibodies)) biosynthesis and granule content

  6. Phenotypic differences between the 7B2 and PC2 (show CBX4 Antibodies) nulls and play a life-or-death role in the ACTH (show POMC Antibodies) hypersecretion syndrome present in both 129 nulls.

  7. phosphorylation of 7B2 functionally inactivates this protein in a manner analogous to the phosphorylating inactivation of BiP (show HSPA5 Antibodies), which impairs its ability to bind substrate

  8. Differential expression of 7B2 may contribute to the difference between B6 and C3H mice not only in glucagon (show GCG Antibodies) production and secretion but also in glucose tolerance.

  9. a role for Scg5 in the modulation of body weight

  10. 7B2 possesses chaperone activity that blocks partially unfolded pro-PC2 (show CBX4 Antibodies) forms from losing catalytic competence and then aggregating.

Human Secretogranin V (7B2 Protein) (SCG5) interaction partners

  1. FAM20C (show FAM20C Antibodies) plays a role in 7B2-mediated proPC2 activation by phosphorylating residue Thr111; and that 7B2 function is regulated by alternative splicing.

  2. 7B2 chaperones blocked the cytotoxic effects of exogenous hIAPP

  3. conclude that 7B2 is a natively disordered protein whose function as an antiaggregant chaperone is likely facilitated by its lack of appreciable secondary structure and tendency to form oligomers

  4. data provide insight into novel functions of 7B2 and establish this neural protein as an anti-aggregation chaperone associated with neurodegenerative disease

  5. the significant effects of SGNE1/7B2 on the growth and apoptosis of glioblastoma cells provide a first proof for a functional implication of SGNE1/7B2 inactivation in the molecular pathology of gliomas.

  6. SGNE1 was overexpressed in gastrointestinal peptide (show SPINK4 Antibodies)-independent ACTH (show POMC Antibodies)-independent macronodular adrenal hyperplasia. hyperplasia

  7. SGNE1 identified as a novel epigenetically silenced gene in medulloblastomas and its inactivation, as well as its inhibitory effect on tumor cell proliferation and focus formation strongly argues for a significant role in medulloblastoma development.

  8. SGNE1 genetic variation does not contribute to obesity and common forms of Type 2 diabetes but may worsen glucose intolerance and insulin (show INS Antibodies) resistance, especially in the background of severe and early onset obesity

Secretogranin V (7B2 Protein) (SCG5) Antigen Profile

Protein Summary

mouse homolog plays a role in the transport and activation of proprotein convertase-2 (PC2)\; may regulate hormone secretion

Gene names and symbols associated with SCG5

  • secretogranin V (scg5) antibody
  • secretory granule, neuroendocrine protein 1 (7B2 protein) (sgne1) antibody
  • secretogranin V (LOC100341807) antibody
  • secretogranin V (Scg5) antibody
  • secretogranin V (7B2 protein) (Scg5) antibody
  • secretogranin V (7B2 protein) (SCG5) antibody
  • 7B2 antibody
  • AI325031 antibody
  • MGC145087 antibody
  • P7B2 antibody
  • Sgne-1 antibody
  • SGNE1 antibody
  • SgV antibody
  • zgc:73132 antibody

Protein level used designations for SCG5

neuroendocrine protein 7B2 , secretogranin V , secretogranin-5 , secretory granule endocrine protein I , secretory granule neuroendocrine protein 1, 7B2 protein , Secretory granule neuroendocrine, protein 1 (7B2 protein) , secretory granule neuroendocrine protein 1 , pituitary polypeptide , prohormone convertase chaperone , secretory granule, neuroendocrine protein 1 (7B2 protein) , neuronal endocrine protein

393699 Danio rerio
496700 Xenopus (Silurana) tropicalis
100341807 Oryctolagus cuniculus
20394 Mus musculus
25719 Rattus norvegicus
6447 Homo sapiens
397110 Sus scrofa
453292 Pan troglodytes
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