SCG5 antibody (AA 27-212)

Catalog No. ABIN7161265

Product Details anti-SCG5 Antibody

Target: SCG5 (Secretogranin V (7B2 Protein) (SCG5))

Binding Specificity: AA 27-212

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCG5 antibody is un-conjugated

Application: ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Neuroendocrine protein 7B2 protein (27-212AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SCG5

Target: SCG5 (Secretogranin V (7B2 Protein) (SCG5))

Alternative Name: SCG5 (SCG5 Products)

Synonyms: zgc:73132 antibody, sgne1 antibody, MGC145087 antibody, 7B2 antibody, AI325031 antibody, Sgne-1 antibody, Sgne1 antibody, P7B2 antibody, SGNE1 antibody, SgV antibody, secretogranin V antibody, scg5 antibody, SCG5 antibody, Scg5 antibody

Background:

Background: Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.

Aliases: SCG5 antibody, SGNE1Neuroendocrine protein 7B2 antibody, Pituitary polypeptide antibody, Secretogranin V antibody, Secretogranin-5 antibody, Secretory granule endocrine protein I) [Cleaved into: N-terminal peptide, C-terminal peptide] antibody

UniProt: P05408