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anti-Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D) Antibodies

Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Additionally we are shipping SEMA4D Proteins (27) and SEMA4D Kits (20) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SEMA4D 306790  
SEMA4D 10507 Q92854
SEMA4D 20354 O09126
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Top anti-SEMA4D Antibodies at antibodies-online.com

Showing 10 out of 232 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse PE FACS Antibody ABIN118824 staining of human peripheral blood lymphocytes 100 Tests Log in to see 6 to 8 Days
$808.50
Details
Human Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of CD100 on a Jurkat cell lysate (Human T-cell leukemia, ATCC TIB-152). 1 µg/mL (lane 1), 0.5 µg/mL (lane 2), 0.25 µg/mL (lane 3) of the mouse anti-CD100 antibody. Immunofluorescence staining of rabbit spleen. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Mouse Rat FITC FACS 100 μL Log in to see 10 to 12 Days
$381.15
Details
Mouse Rat Un-conjugated FACS 0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Mouse APC FACS   100 Tests Log in to see 6 to 8 Days
$511.50
Details
Human Mouse APC FACS 100 Tests Log in to see 8 to 10 Days
$566.50
Details
Human Mouse Un-conjugated FACS, IP, WB   25 μg Log in to see 6 to 8 Days
$176.00
Details
Human Mouse FITC FACS   25 μg Log in to see 6 to 8 Days
$198.00
Details
Human Mouse FITC FACS, ICFC 100 Tests Log in to see 10 to 12 Days
$211.97
Details
Mouse Rat FITC ELISA (Detection), ELISPOT (Detection) 100 μg Log in to see 10 to 12 Days
$222.85
Details

SEMA4D Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SEMA4D Antibodies

  1. Mouse (Murine) Monoclonal SEMA4D Primary Antibody for ELISA (Detection), ELISPOT (Detection) - ABIN2661347 : Kishihara, Penninger, Wallace, Kündig, Kawai, Wakeham, Timms, Pfeffer, Ohashi, Thomas: Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice. in Cell 1993 (PubMed)
    Show all 6 references for ABIN2661347

  2. Mouse (Murine) Monoclonal SEMA4D Primary Antibody for FACS - ABIN1449183 : Maas, Chan, Parker, Slater, Moore, Olsen, Aune: Cutting edge: molecular portrait of human autoimmune disease. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Show all 5 references for ABIN1449183

  3. Human Monoclonal SEMA4D Primary Antibody for FACS, ICFC - ABIN2661450 : Bougeret, Mansur, Dastot, Schmid, Mahouy, Bensussan, Boumsell: Increased surface expression of a newly identified 150-kDa dimer early after human T lymphocyte activation. in Journal of immunology (Baltimore, Md. : 1950) 1992 (PubMed)
    Show all 4 references for ABIN2661450

  4. Human Monoclonal SEMA4D Primary Antibody for FACS - ABIN319838 : Yoshino, Ami, Terao, Tashiro, Honda: Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. in Experimental animals / Japanese Association for Laboratory Animal Science 2000 (PubMed)
    Show all 3 references for ABIN319838

  5. Mouse (Murine) Monoclonal SEMA4D Primary Antibody for FACS - ABIN2853598 : Moreau-Fauvarque, Kumanogoh, Camand, Jaillard, Barbin, Boquet, Love, Jones, Kikutani, Lubetzki, Dusart, Chédotal: The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 (PubMed)
    Show all 2 references for ABIN2853598

  6. Human Monoclonal SEMA4D Primary Antibody for IF, IP - ABIN968101 : Hall, Boumsell, Schultze, Boussiotis, Dorfman, Cardoso, Bensussan, Nadler, Freeman: Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation. in Proceedings of the National Academy of Sciences of the United States of America 1996 (PubMed)

  7. Human Monoclonal SEMA4D Primary Antibody for FACS - ABIN319839 : Aversa, Waugh, Bishop, Hall: Use of monoclonal antibodies to study in vivo and in vitro-activated lymphocytes. in Transplantation proceedings 1989 (PubMed)

More Antibodies against SEMA4D Interaction Partners

Human Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D) interaction partners

  1. Semaphorin 4D Promotes Skeletal Metastasis in Breast Cancer.

  2. this study describes a novel immunosuppressive role for Sema4D in head and neck squamous cell carcinoma through induction of myeloid derived suppressor cells

  3. Plexin-B1 (show PLXNB1 Antibodies) induces cutaneous squamous cell carcinoma cell proliferation, migration, and invasion by interacting with Sema4D. Plexin-B1 (show PLXNB1 Antibodies) might serve as a useful biomarker and/or as a novel therapeutic target for cSCC (show CYP11A1 Antibodies).

  4. Results show that decreased expression of Sema4D, plexin-B1 (show PLXNB1 Antibodies) and -B2 was associated with local recurrence and poor prognosis of breast neoplasm.

  5. Blocking of CD100, plexin B1 (show PLXNB1 Antibodies) and/or B2 in adhesion experiments have shown that both CD100 and plexins act as adhesion molecules involved in monocyte-endothelial cell binding.

  6. Suggest that HIF-1alpha (show HIF1A Antibodies) and Sema4D expression correlates with histological tumor type, TNM (show ODZ1 Antibodies) stage, and lymphatic metastasis in colorectal carcinoma.

  7. A positive feedback loop involving sSema4D/IL-6 (show IL6 Antibodies) and TNFalpha (show TNF Antibodies)/ADAMTS-4 (show ADAMTS4 Antibodies) may contribute to the pathogenesis of rheumatoid arthritis.

  8. Sema4D contributes to enhanced invasion and tumor progression through increased motility of cervical cancer and VEGF-C (show VEGFC Antibodies)/-D-mediated lymphangiogenesis.

  9. SEMA4D might possibly serve as a reliable tool for early and accurate prediction of EOC poor prognosis.

  10. results suggest that the contribution of Sema4D in platelets applies to ITAM-containing receptors as a class

Mouse (Murine) Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D) interaction partners

  1. Sema4D-deficiency affected ischemia-induced microglial activation in morphology, iNOS (show NOS2 Antibodies) expression, and proliferation, and this deficiency most likely resulted in moderation of cytotoxicity and locomotor behavioral abnormality after cerebral ischemia

  2. The addition of recombinant Sema4D to Sema4D/ vaginal epithelial cells in culture significantly enhanced apoptosis of the vaginal epithelial cells.

  3. Sema4D may be an essential apoptosis-inducing ligand that acts downstream of estrogen action in vaginal epithelium during pubertal tissue remodeling.

  4. therapeutic effects via bone-targeting systems featuring interference of Sema4d are able to partly counteract alveolar bone loss caused by osteoporosis.

  5. CD100-mediated signals are critical for effective activation of gammadelta IEL to produce growth factors, including KGF (show FGF7 Antibodies)-1, that are required for healing of the colon epithelium during colitis.

  6. Deletion of plexin-B1 (show PLXNB1 Antibodies), the high affinity receptor for semaphorin 4D, significantly (one-way ANOVA; p < 0.001) reduced thrombus weight (- 40%) in oxidative venous thrombosis.

  7. Data indicate neuroimmune semaphorin 4D (Sema4D) as an important regulator of Th2-driven lung pathophysiology and as a potential target for a combinatory disease immunotherapy.

  8. Sema (show SEMA3B Antibodies) 4D/CD100 is not only a ligand for plexin B1 (show PLXNB1 Antibodies) but also a direct signaling receptor in mediating Sema (show SEMA3B Antibodies) 4D/CD100-plexin B's biological functions.

  9. CD100 deficiency in vivo resulted in delayed repair of cutaneous wounds due to a disrupted gamma-delta T cell response to keratinocyte damage.

  10. Sema4D may act as an intrinsic inhibitory regulator of oligodendrocyte differentiation by promoting apoptosis.

SEMA4D Antigen Profile

Protein Summary

Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system\; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA (By similarity).

Gene names and symbols associated with SEMA4D

  • sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D (Sema4d) antibody
  • sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D (SEMA4D) antibody
  • C9orf164 antibody
  • CD100 antibody
  • COLL-4 antibody
  • M-sema-G antibody
  • Semacl2 antibody
  • Semaj antibody
  • Semcl2 antibody

Protein level used designations for SEMA4D

semaphorin-4D , A8 , BB18 , GR3 , sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D , M-sema G , sema J , semaphorin H , semaphorin-C-like 2 , semaphorin-J , semaphorin 4D , collapsin-4

GENE ID SPECIES
306790 Rattus norvegicus
100152598 Sus scrofa
785942 Bos taurus
10507 Homo sapiens
20354 Mus musculus
100346590 Oryctolagus cuniculus
100732888 Cavia porcellus
476350 Canis lupus familiaris
396331 Gallus gallus
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