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SHBG encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. Additionally we are shipping Sex Hormone Binding Globulin Kits (50) and Sex Hormone Binding Globulin Proteins (21) and many more products for this protein.
Showing 10 out of 193 products:
Human Polyclonal SHBG Primary Antibody for EIA, WB - ABIN954796
Canzian, Cox, Setiawan, Stram, Ziegler, Dossus, Beckmann, Blanché, Barricarte, Berg, Bingham, Buring, Buys, Calle, Chanock, Clavel-Chapelon, DeLancey, Diver, Dorronsoro, Haiman, Hallmans, Hankinson, Hunter, Hüsing, Isaacs, Khaw, Kolonel, Kraft, Le Marchan: Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium. in Human molecular genetics 2010
Human Polyclonal SHBG Primary Antibody for IF (p), IHC (p) - ABIN739860
Liu, Su, Hao, Chen, Liu, Liao, Li: Overexpression of PRL7D1 in Leydig Cells Causes Male Reproductive Dysfunction in Mice. in International journal of molecular sciences 2016
characterization of the zebrafish SHBG gene and protein through molecular biological, biochemical, and informatics approaches
SHBG controls the flux of sex steroids across fish.
A wave of apoptosis during the pre-pubertal period is required for normal spermatogenesis to develop, and our data indicate that this apoptotic wave may be regulated by ABP and/or androgens.
USF transcription factors repress SHBG transcription in Sertoli cells through an interaction with FP4 within its proximal promoter
monosaccharide-induced lipogenesis reduced hepatic HNF-4alpha (show HNF4A Antibodies) levels, which in turn attenuated SHBG expression.
In hormonal contraceptive users, SHBG was positively associated with both activated protein C (show PROC Antibodies) (APC (show APC Antibodies)) resistance and baseline TG, and protein S and prothrombin (show F2 Antibodies) were important mediators. These data provide further evidence that SHBG may be used as a biomarker in assessing prothrombotic profile of hormonal contraception.
No significant differences were observed in serum ABP (show ABP1 Antibodies) levels in all male farmers between the two groups with different fluoride exposure. These results supported that excess fluoride exposure decreased serum T levels of male farmers with age-specificity.
results indicated that there was a significant association between migraine and gene-gene interaction among the CYP19A1 (show CYP19A1 Antibodies), FSHR (show FSHR Antibodies), ESR1 (show ESR1 Antibodies) and NRIP1 (show NRIP1 Antibodies).
Polymorphisms of SHBG or the neighboring genes were associated with SHBG levels or BMD (show BEST1 Antibodies) and osteoporosis
high SHBG predicts incident clinical and radiographic vertebral fractures in elderly men.
After early childhood, serum sex hormone-binding globulin declines to a nadir in males at the age of 20 years and remains stable till the sixth decade with a gradual, progressive rise thereafter. In females, the sex hormone-binding globulin nadir is reached earlier with levels rising gradually and progressively with age thereafter and accelerating after the age of 70 years
higher SHBG (but not testosterone or estradiol) is an independent risk factor for vertebral fractures in older men.
We found that elevated levels of estradiol and SHBG in HT [Hormone therapy] users were associated with elevated levels of CRP (show CRP Antibodies) and lower levels of TFPI (show TFPI Antibodies), both of which may be related to a prothrombotic milieu in HT [Hormone therapy ]users.
There was a drop in SHBG levels in the first week of smoking cessation and levels continued to remain low.
SHBG was higher in both obese and non-obese PCOS patients compared to healthy controls.
Three novel mutations with very damaging effect on the protein structure, according to SIFT and Polyphen-2, were detected in GART, SHBG and SLC37A2 genes.
This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein binds each steroid molecule as a dimer formed from identical or nearly identical monomers. The use of alternate promoters and alternatively spliced transcripts have been described. Multiple transcript variants encoding different isoforms have been found for this gene.
, sex hormone-binding globulin
, sex steroid-binding protein
, testis-specific androgen-binding protein
, Sex hormone binding globulin or androgen-binding protein (other gene product from ABP gene)
, testosterone-binding beta-globulin
, testosterone-estradiol-binding globulin
, testosterone-estrogen-binding globulin
, androgen binding protein 1 (296 AA)
, sex hormone binding globulin
, sex hormone-binding globulin protein