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SHBG encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. Additionally we are shipping Sex Hormone Binding Globulin Kits (62) and Sex Hormone Binding Globulin Proteins (21) and many more products for this protein.
Showing 10 out of 154 products:
Human Polyclonal SHBG Primary Antibody for EIA, WB - ABIN954796
Canzian, Cox, Setiawan, Stram, Ziegler, Dossus, Beckmann, Blanché, Barricarte, Berg, Bingham, Buring, Buys, Calle, Chanock, Clavel-Chapelon, DeLancey, Diver, Dorronsoro, Haiman, Hallmans, Hankinson, Hunter, Hüsing, Isaacs, Khaw, Kolonel, Kraft, Le Marchan: Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium. in Human molecular genetics 2010
characterization of the zebrafish SHBG gene and protein through molecular biological, biochemical, and informatics approaches
SHBG controls the flux of sex steroids across fish.
A wave of apoptosis during the pre-pubertal period is required for normal spermatogenesis to develop, and our data indicate that this apoptotic wave may be regulated by ABP and/or androgens.
USF transcription factors repress SHBG transcription in Sertoli cells through an interaction with FP4 within its proximal promoter
monosaccharide-induced lipogenesis reduced hepatic HNF-4alpha (show HNF4A Antibodies) levels, which in turn attenuated SHBG expression.
There was a drop in SHBG levels in the first week of smoking cessation and levels continued to remain low.
SHBG was higher in both obese and non-obese PCOS patients compared to healthy controls.
Specific SHBG variants affecting serum SHBG levels and SHBG haplotypes are associated with polycystic ovary syndrome, suggesting the role for SHBG as polycystic ovary syndrome candidate gene.
overlapping of interacting amino acid residues between phthalate compounds and natural ligand, dihydrotestosterone, suggested potential disrupting activity of phthalates in the endocrine homeostasis function of SHBG
Data suggest that, in endurance runners using endurance training followed by strength training, an initial reduction in testosterone/SHBG ratio is seen after 12 weeks followed by large increase in weeks 12-24 (as compared to endurance training alone).
SHBG levels were lower in women with polycystic ovary syndrome compared to controls.
the TAAAA repeat polymorphism was shown to not be a major determinant of the PCOS status, although it influenced serum SHBG levels in females with PCOS.
SHBG overexpression reduced weight gain but did not change the metabolic profile of obese mice. SHBG down-regulation during obesity development involved changes in liver HNF4alpha (show HNF4A Antibodies) and PPARgamma (show PPARG Antibodies) mRNA and protein levels.
prognostic role of testosterone in men with type 2 diabetes mellitus (T2DM) is influenced by its carrier protein sex hormone-binding globulin
data suggest that higher SHBG levels are associated with worse verbal memory.
Three novel mutations with very damaging effect on the protein structure, according to SIFT and Polyphen-2, were detected in GART, SHBG and SLC37A2 genes.
This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein binds each steroid molecule as a dimer formed from identical or nearly identical monomers. The use of alternate promoters and alternatively spliced transcripts have been described. Multiple transcript variants encoding different isoforms have been found for this gene.
, sex hormone-binding globulin
, sex steroid-binding protein
, testis-specific androgen-binding protein
, Sex hormone binding globulin or androgen-binding protein (other gene product from ABP gene)
, testosterone-binding beta-globulin
, testosterone-estradiol-binding globulin
, testosterone-estrogen-binding globulin
, androgen binding protein 1 (296 AA)
, sex hormone binding globulin
, sex hormone-binding globulin protein