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anti-Slit Homolog 2 (Drosophila) (SLIT2) Antibodies

acts as a ligand for glypican-1, a heparan sulfate proteoglycan; may play a role in neurogenesis and midline development. Additionally we are shipping Slit Homolog 2 (Drosophila) Kits (14) and Slit Homolog 2 (Drosophila) Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLIT2 9353 O94813
SLIT2 20563 Q9R1B9
SLIT2 360272  
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Top anti-Slit Homolog 2 (Drosophila) Antibodies at antibodies-online.com

Showing 10 out of 79 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Dog Goat Un-conjugated EIA, IHC (p) AP31152PU-N SLIT2 antibody staining of Paraffin Embedded Human Spinal Cord at 4 µg/ml. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated FACS, IHC (p) 1 mL Log in to see 6 to 8 Days
$797.50
Details
Human Goat Un-conjugated IHC, ELISA   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IHC (p) Flow cytometric analysis of rabbit anti-SLIT2 (SP122) antibody in SH-SY5Y (green) compare to negative control of rabbit IgG (blue). 7 mL Log in to see 2 to 3 Days
$367.00
Details
Human Rabbit Un-conjugated IHC (p) 7 mL Log in to see 2 to 3 Days
$237.00
Details
Human Rabbit Un-conjugated IHC (p) AP22401PU-N SLIT2 antibody staining of Human prostate adenocarcinoma. 1 mL Log in to see 6 to 8 Days
$599.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot using Affinity Purified anti-SLIT-2 antibody shows detection of a band at ~165 kDa (lane 1) corresponding to SLIT-2 present in a chicken spinal cord whole cell lysate (arrowhead). Approximately 30 µg of lysate was separated on a 4-20% Tris-Glycine gel by SDS-PAGE and transferred onto nitrocellulose. After blocking the membrane was probed with the primary antibody diluted to 1:1,350. Reaction occurred overnight at 4° C followed by washes and reaction with a 1:10,000 dilution of IRDye800 conjugated Gt-a-Rabbit IgG [H&L] MX (611-132-122) for 45 min at room temperature (800 nm channel, green). Molecular weight estimation was made by comparison to prestained MW markers in lane M (700 nm channel, red). IRDye™800 fluorescence image was captured using the Odyssey® Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc. Other detection systems will yield similar results. 100 μg Log in to see 2 to 3 Days
$369.00
Details
Human Goat Un-conjugated IHC, ELISA 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Cow Rabbit Un-conjugated ELISA, IHC, WB 0.1 mg Log in to see 5 to 7 Days
$553.88
Details

SLIT2 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Slit Homolog 2 (Drosophila) Antibodies

  1. Cow (Bovine) Polyclonal SLIT2 Primary Antibody for EIA, WB - ABIN401286 : Prasad, Fernandis, Rao, Ganju: Slit protein-mediated inhibition of CXCR4-induced chemotactic and chemoinvasive signaling pathways in breast cancer cells. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN401286

  2. Human Polyclonal SLIT2 Primary Antibody for IHC, ELISA - ABIN185654 : Lin, Rao, Isacson: Netrin-1 and slit-2 regulate and direct neurite growth of ventral midbrain dopaminergic neurons. in Molecular and cellular neurosciences 2005 (PubMed)

More Antibodies against Slit Homolog 2 (Drosophila) Interaction Partners

Zebrafish Slit Homolog 2 (Drosophila) (SLIT2) interaction partners

  1. These data supports a model whereby Wnt signaling through Frizzled-3a attenuates expression of Slit2 in the rostral midline of the forebrain.

  2. In embryonic axon tracts, Robo2 (show ROBO2 Antibodies) responds to signals from slit2 and slit3 (show SLIT3 Antibodies).

  3. Data show that Hedgehog (show SHH Antibodies) signaling is required for commissure formation, glial bridge formation, and the restricted expression of the guidance molecules slit1a, slit2, slit3 (show SLIT3 Antibodies) and sema3d (show SEMA3D Antibodies).

Xenopus laevis Slit Homolog 2 (Drosophila) (SLIT2) interaction partners

  1. Slit acts via Robo2 (show ROBO2 Antibodies) in dendrites as a branching/growth factor but not in guidance, while Robo2 (show ROBO2 Antibodies) and Robo3 (show ROBO3 Antibodies) function in concert in axons to mediate axonal interactions and respond to Slits as guidance factors

Human Slit Homolog 2 (Drosophila) (SLIT2) interaction partners

  1. Overexpression of Slit2 induces its tumor suppressive effects in Breast cancer.

  2. Significantly increased serum Slit2 (show SLIT3 Antibodies) levels and hepatic expression of Slit2 (show SLIT3 Antibodies) and Robo1 (show ROBO1 Antibodies) were observed in patients with liver fibrosis.

  3. our findings indicated that Slit2 (show SLIT3 Antibodies)/Robo1 (show ROBO1 Antibodies) axis possibly be regarded as a significant clinical parameter for predicting brain metastasis in breast cancer patients.

  4. These results suggest that Slit2 (show SLIT3 Antibodies)/Robo1 (show ROBO1 Antibodies) binding exerts an effect on cell migration, which is negatively regulated by Robo4 (show ROBO4 Antibodies), and Robo1 (show ROBO1 Antibodies) may function by interacting with CdGAP (show ARHGAP31 Antibodies) in HUVECs.

  5. VEGFR2 (show KDR Antibodies) activation was not affected by Slit2 (show SLIT3 Antibodies), but eNOS (show NOS3 Antibodies) phosphorylation was diminished

  6. Slit2-exon 15 splicing variants have different roles in angiogenesis and HUVEC permeability

  7. Data indicate that SLIT2 (show SLIT3 Antibodies), miR (show MLXIP Antibodies)-218-1, RET (show RET Antibodies)/PLAG1 (show PLAG1 Antibodies) and SLIT2 (show SLIT3 Antibodies)/ROBO1 (show ROBO1 Antibodies) pathway involved in Hirschsprung's disease.

  8. Slit2 (show SLIT3 Antibodies)/Robo1 (show ROBO1 Antibodies) signaling promotes intestinal tumorigenesis through Src (show SRC Antibodies)-mediated activation of the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway.

  9. In this review, we summarize recent findings demonstrating that the neuronal guidance cues, Slit and Roundabout (show ROBO1 Antibodies) (Robo), prevent the migration of multiple leukocyte subsets towards diverse inflammatory chemoattractants.

  10. Inactivation of SLIT2 (show SLIT3 Antibodies) and/or ROBO1 (show ROBO1 Antibodies) is one of the early events in development of dysplastic lesions of head and neck and has prognostic importance.

Mouse (Murine) Slit Homolog 2 (Drosophila) (SLIT2) interaction partners

  1. Robo1-Slit2 interaction required for pathfinding mechanism essential to establish the functionally important habenulo-interpeduncular connection.

  2. Together, these observations suggest that Slit2 serves as a factor utilized by muscle Ctnnb1 (show CTNNB1 Antibodies) to direct presynaptic differentiation.

  3. Slit2 acts as a repellant cue to mediate axon guidance in the formation of the anterior commissure.

  4. Slit2/Robo1 (show ROBO1 Antibodies) signaling promotes intestinal tumorigenesis through Src (show SRC Antibodies)-mediated activation of the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway.

  5. the two genes neuropeptide Y (Npy (show NPY Antibodies)) and Slit homolog 2 (Drosophila) (Slit2) gradually increase during aging, and upon suppression of these two genes

  6. Data shows that modulation of angiostatic factor Slit2 by EphA2 receptor regulates endothelial responses to VEGF-mediated angiogenesis and tumor neovascularization.

  7. administration of Slit2 to atherosclerosis-prone LDL receptor (show LDLR Antibodies)-deficient mice inhibited monocyte recruitment to nascent atherosclerotic lesions.

  8. Results provide novel evidence that low expression of SLIT2 correlates with poor prognosis and promotes metastasis in ESCC, which may be regulated by the Cdc42 (show CDC42 Antibodies)-mediated pathways.

  9. Slit2 may promote angiogenesis by upregulating Robo1 (show ROBO1 Antibodies) and activating the VEGFR2 (show KDR Antibodies)-ERK1/2 (show MAPK1/3 Antibodies) pathway.

  10. Mutations of the SLIT2-ROBO2 (show ROBO2 Antibodies) pathway genes SLIT2 and SRGAP1 (show SRGAP1 Antibodies) confer risk for congenital anomalies of the kidney and urinary tract

Slit Homolog 2 (Drosophila) (SLIT2) Antigen Profile

Protein Summary

acts as a ligand for glypican-1, a heparan sulfate proteoglycan\; may play a role in neurogenesis and midline development

Gene names and symbols associated with SLIT2

  • slit (Drosophila) homolog 2 (slit2) antibody
  • slit homolog 2 (slit2) antibody
  • slit homolog 2 (Drosophila) (SLIT2) antibody
  • slit homolog 2 (Drosophila) (Slit2) antibody
  • Drad-1 antibody
  • E030015M03Rik antibody
  • E130320P19Rik antibody
  • mKIAA4141 antibody
  • Slil3 antibody
  • Slit antibody
  • Slit-2 antibody
  • slit2-a antibody

Protein level used designations for SLIT2

slit homolog 2 protein , slit-2 , downregulated during adipocyte differentiation-1 , neurogenic extracellular slit protein

GENE ID SPECIES
80353 Danio rerio
394404 Xenopus laevis
9353 Homo sapiens
373967 Gallus gallus
534164 Bos taurus
20563 Mus musculus
360272 Rattus norvegicus
595148 Canis lupus familiaris
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