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anti-Slit Homolog 2 (Drosophila) (SLIT2) Antibodies

acts as a ligand for glypican-1, a heparan sulfate proteoglycan; may play a role in neurogenesis and midline development. Additionally we are shipping Slit Homolog 2 (Drosophila) Kits (14) and Slit Homolog 2 (Drosophila) Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLIT2 9353 O94813
SLIT2 20563 Q9R1B9
SLIT2 360272  
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Top anti-Slit Homolog 2 (Drosophila) Antibodies at antibodies-online.com

Showing 10 out of 82 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Dog Goat Un-conjugated EIA, IHC (p) AP31152PU-N SLIT2 antibody staining of Paraffin Embedded Human Spinal Cord at 4 µg/ml. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated IHC (p), IHC, ELISA Immunohistochemistry-Paraffin: Slit2 Antibody [ABIN2515007] - (4ug/ml) staining of paraffin embedded Human Spinal Cord. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining. 0.1 mg Log in to see 5 to 7 Days
$408.19
Details
Human Rabbit Un-conjugated FACS, IHC (p) 1 mL Log in to see 6 to 8 Days
$808.50
Details
Human Goat Un-conjugated IHC, ELISA   100 μg Log in to see 4 to 5 Days
$326.89
Details
Human Rabbit Un-conjugated IHC (p) Flow cytometric analysis of rabbit anti-SLIT2 (SP122) antibody in SH-SY5Y (green) compare to negative control of rabbit IgG (blue). 7 mL Log in to see 2 to 3 Days
$374.00
Details
Human Rabbit Un-conjugated IHC (p) 7 mL Log in to see 2 to 3 Days
$242.00
Details
Human Rat PE FACS Detection of Slit2 in CHO Chinese Hamster Cell Line Transfected with human Slit2 by Flow Cytometry. CHO Chinese hamster ovary cell line transfected with human Slit2 was stained with Rat Anti-Human/Mouse Slit2 PE-conjugated Antigen Affinity-purified Monoclonal Antibody. Detection of Slit2 in CHO Chinese Hamster Cell Line Transfected with mouse Slit2 by Flow Cytometry. CHO Chinese hamster ovary cell line transfected with mouse Slit2 was stained with Rat Anti-Human/Mouse Slit2 PE-conjugated Antigen Affinity-purified Monoclonal Antibody. 25 Tests Log in to see 6 to 7 Days
$249.38
Details
Human Rat Allophycocyanin FACS Detection of Slit2 in CHO Chinese Hamster Cell Line Transfected with human Slit2 by Flow Cytometry. CHO Chinese hamster ovary cell line transfected with human Slit2 was stained with Rat Anti-Human/Mouse Slit2 APC-conjugated Monoclonal Antibody. Detection of Slit2 in CHO Chinese Hamster Cell Line Transfected with mouse Slit2 by Flow Cytometry. CHO Chinese hamster ovary cell line transfected with mouse Slit2 was stained with Rat Anti-Human/Mouse Slit2 APC-conjugated Monoclonal Antibody. 25 Tests Log in to see 6 to 7 Days
$275.63
Details
Human Rabbit Un-conjugated IHC (p) AP22401PU-N SLIT2 antibody staining of Human prostate adenocarcinoma. 1 mL Log in to see 6 to 8 Days
$610.50
Details

SLIT2 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Slit Homolog 2 (Drosophila) Antibodies

  1. Cow (Bovine) Polyclonal SLIT2 Primary Antibody for EIA, WB - ABIN401286 : Prasad, Fernandis, Rao, Ganju: Slit protein-mediated inhibition of CXCR4-induced chemotactic and chemoinvasive signaling pathways in breast cancer cells. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN401286

  2. Human Polyclonal SLIT2 Primary Antibody for IHC (p), IHC - ABIN251500 : Lin, Rao, Isacson: Netrin-1 and slit-2 regulate and direct neurite growth of ventral midbrain dopaminergic neurons. in Molecular and cellular neurosciences 2005 (PubMed)

More Antibodies against Slit Homolog 2 (Drosophila) Interaction Partners

Zebrafish Slit Homolog 2 (Drosophila) (SLIT2) interaction partners

  1. These data supports a model whereby Wnt signaling through Frizzled-3a attenuates expression of Slit2 in the rostral midline of the forebrain.

  2. In embryonic axon tracts, Robo2 (show ROBO2 Antibodies) responds to signals from slit2 and slit3 (show SLIT3 Antibodies).

  3. Data show that Hedgehog (show SHH Antibodies) signaling is required for commissure formation, glial bridge formation, and the restricted expression of the guidance molecules slit1a, slit2, slit3 (show SLIT3 Antibodies) and sema3d (show SEMA3D Antibodies).

Xenopus laevis Slit Homolog 2 (Drosophila) (SLIT2) interaction partners

  1. Slit acts via Robo2 (show ROBO2 Antibodies) in dendrites as a branching/growth factor but not in guidance, while Robo2 (show ROBO2 Antibodies) and Robo3 (show ROBO3 Antibodies) function in concert in axons to mediate axonal interactions and respond to Slits as guidance factors

Human Slit Homolog 2 (Drosophila) (SLIT2) interaction partners

  1. Study shows that Slit2 (show SLIT3 Antibodies) mRNA and protein levels were significantly reduced in papillary thyroid cancer (PTC (show F9 Antibodies)) specimens and implicates Slit2 (show SLIT3 Antibodies) functions as a negative regulator in the development and progression of PTC (show F9 Antibodies).

  2. Overexpression of Slit2 induces its tumor suppressive effects in Breast cancer.

  3. Significantly increased serum Slit2 (show SLIT3 Antibodies) levels and hepatic expression of Slit2 (show SLIT3 Antibodies) and Robo1 (show ROBO1 Antibodies) were observed in patients with liver fibrosis.

  4. our findings indicated that Slit2 (show SLIT3 Antibodies)/Robo1 (show ROBO1 Antibodies) axis possibly be regarded as a significant clinical parameter for predicting brain metastasis in breast cancer patients.

  5. These results suggest that Slit2 (show SLIT3 Antibodies)/Robo1 (show ROBO1 Antibodies) binding exerts an effect on cell migration, which is negatively regulated by Robo4 (show ROBO4 Antibodies), and Robo1 (show ROBO1 Antibodies) may function by interacting with CdGAP (show ARHGAP31 Antibodies) in HUVECs.

  6. VEGFR2 (show KDR Antibodies) activation was not affected by Slit2 (show SLIT3 Antibodies), but eNOS (show NOS3 Antibodies) phosphorylation was diminished

  7. Slit2-exon 15 splicing variants have different roles in angiogenesis and HUVEC permeability

  8. Data indicate that SLIT2 (show SLIT3 Antibodies), miR (show MLXIP Antibodies)-218-1, RET (show RET Antibodies)/PLAG1 (show PLAG1 Antibodies) and SLIT2 (show SLIT3 Antibodies)/ROBO1 (show ROBO1 Antibodies) pathway involved in Hirschsprung's disease.

  9. Slit2 (show SLIT3 Antibodies)/Robo1 (show ROBO1 Antibodies) signaling promotes intestinal tumorigenesis through Src (show SRC Antibodies)-mediated activation of the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway.

  10. In this review, we summarize recent findings demonstrating that the neuronal guidance cues, Slit and Roundabout (show ROBO1 Antibodies) (Robo), prevent the migration of multiple leukocyte subsets towards diverse inflammatory chemoattractants.

Mouse (Murine) Slit Homolog 2 (Drosophila) (SLIT2) interaction partners

  1. In mice with oxygen-induced retinopathy (OIR), the expression level of miR-218 was significantly downregulated. Robo1 expression was suppressed by miR-218. Furthermore, in the mice with OIR, the expression level of miR-218 was significantly downregulated, and that of miR-218-1 and its host gene, Slit2, was concomitantly downregulated as well.

  2. Slit2 induces a robust activation of PKA signaling, which is required for its prothermogenic activity.

  3. Robo1-Slit2 interaction required for pathfinding mechanism essential to establish the functionally important habenulo-interpeduncular connection.

  4. Together, these observations suggest that Slit2 serves as a factor utilized by muscle Ctnnb1 (show CTNNB1 Antibodies) to direct presynaptic differentiation.

  5. Slit2 acts as a repellant cue to mediate axon guidance in the formation of the anterior commissure.

  6. Slit2/Robo1 (show ROBO1 Antibodies) signaling promotes intestinal tumorigenesis through Src (show SRC Antibodies)-mediated activation of the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway.

  7. the two genes neuropeptide Y (Npy (show NPY Antibodies)) and Slit homolog 2 (Drosophila) (Slit2) gradually increase during aging, and upon suppression of these two genes

  8. Data shows that modulation of angiostatic factor Slit2 by EphA2 receptor regulates endothelial responses to VEGF-mediated angiogenesis and tumor neovascularization.

  9. administration of Slit2 to atherosclerosis-prone LDL receptor (show LDLR Antibodies)-deficient mice inhibited monocyte recruitment to nascent atherosclerotic lesions.

  10. Results provide novel evidence that low expression of SLIT2 correlates with poor prognosis and promotes metastasis in ESCC, which may be regulated by the Cdc42 (show CDC42 Antibodies)-mediated pathways.

Slit Homolog 2 (Drosophila) (SLIT2) Antigen Profile

Protein Summary

acts as a ligand for glypican-1, a heparan sulfate proteoglycan\; may play a role in neurogenesis and midline development

Gene names and symbols associated with SLIT2

  • slit (Drosophila) homolog 2 (slit2) antibody
  • slit homolog 2 (slit2) antibody
  • slit homolog 2 (Drosophila) (SLIT2) antibody
  • slit homolog 2 (Drosophila) (Slit2) antibody
  • Drad-1 antibody
  • E030015M03Rik antibody
  • E130320P19Rik antibody
  • mKIAA4141 antibody
  • Slil3 antibody
  • Slit antibody
  • Slit-2 antibody
  • slit2-a antibody

Protein level used designations for SLIT2

slit homolog 2 protein , slit-2 , downregulated during adipocyte differentiation-1 , neurogenic extracellular slit protein

GENE ID SPECIES
80353 Danio rerio
394404 Xenopus laevis
9353 Homo sapiens
373967 Gallus gallus
534164 Bos taurus
20563 Mus musculus
360272 Rattus norvegicus
595148 Canis lupus familiaris
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