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anti-Snail Homolog 1 (Drosophila) (SNAI1) Antibodies

The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. Additionally we are shipping Snail Homolog 1 (Drosophila) Kits (9) and Snail Homolog 1 (Drosophila) Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SNAI1 6615 O95863
SNAI1 116490  
SNAI1 20613 Q02085
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Top anti-Snail Homolog 1 (Drosophila) Antibodies at antibodies-online.com

Showing 10 out of 142 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-SNAI1 Antibody Titration: 1ug/mlPositive Control: 721_B cell lysate IHC Suggested Anti-SNAI1 Antibody Titration: 4-8ug/mlTissue: Human Kidney, epithelial cells of renal tube (indicated with arrows)Magnification:400X 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from HT29 cells, using SNAI1 (Phospho-Ser246) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HuvEc cells, using SNAI1 (Phospho-Ser246) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-SNAI1 Antibody (N-term R8) (ABIN388812) in mouse lung tissue lysates (35 µg/lane). SNAI1(arrow) was detected using the purified polyclonal antibody. Western blot analysis of SNAI1(arrow) using rabbit polyclonal SNAI1 Antibody (N-term R8) (ABIN388812). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the SNAI1 gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 10 to 12 Days
$375.38
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HT29 cells, using SNAI1 (Ab-246) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SNAI1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SNAI1. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Immunohistochemistry analysis of SNAI1 antibody in paraffin-embedded Human lung carcinoma tissue. Western blot (WB) analysis of SNAI 1 antibody at 1/500 dilution: 0.1 mg Log in to see 6 to 8 Days
$390.50
Details

SNAI1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Rat (Rattus)
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Mouse (Murine) ,
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Top referenced anti-Snail Homolog 1 (Drosophila) Antibodies

  1. Human Polyclonal SNAI1 Primary Antibody for EIA, WB - ABIN4620466 : Batlle, Sancho, Francí, Domínguez, Monfar, Baulida, García De Herreros: The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. in Nature cell biology 2000 (PubMed)
    Show all 5 references for ABIN4620466

  2. Human Polyclonal SNAI1 Primary Antibody for IF, IHC (p) - ABIN498268 : Feng, Di, Tao, Chang, Lu, Fan, Shan, Li, Yang: PDK1 regulates vascular remodeling and promotes epithelial-mesenchymal transition in cardiac development. in Molecular and cellular biology 2010 (PubMed)
    Show all 5 references for ABIN498268

  3. Human Polyclonal SNAI1 Primary Antibody for EIA, WB - ABIN357452 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 5 references for ABIN357452

  4. Human Polyclonal SNAI1 Primary Antibody for EIA, IHC (p) - ABIN357449 : Imai, Horiuchi, Wang, Oka, Ohira, Nikaido, Konishi: Hypoxia attenuates the expression of E-cadherin via up-regulation of SNAIL in ovarian carcinoma cells. in The American journal of pathology 2003 (PubMed)
    Show all 5 references for ABIN357449

  5. Human Polyclonal SNAI1 Primary Antibody for EIA - ABIN357450 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002 (PubMed)
    Show all 5 references for ABIN357450

  6. Human Polyclonal SNAI1 Primary Antibody for IHC, WB - ABIN2777858 : Zhou, Deng, Xia, Xu, Li, Gunduz, Hung: Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. in Nature cell biology 2004 (PubMed)
    Show all 4 references for ABIN2777858

  7. Human Monoclonal SNAI1 Primary Antibody for IHC, WB - ABIN2452265 : Qin, He, Tang, Ye, Dang, Lu, Wang, Li, Yan, Ma: MicroRNAs Provide Feedback Regulation of Epithelial-Mesenchymal Transition Induced by Growth Factors. in Journal of cellular physiology 2015 (PubMed)

  8. Human Polyclonal SNAI1 Primary Antibody for IF, ELISA - ABIN1531754 : Paznekas, Okajima, Schertzer, Wood, Jabs: Genomic organization, expression, and chromosome location of the human SNAIL gene (SNAI1) and a related processed pseudogene (SNAI1P). in Genomics 2000 (PubMed)

  9. Human Polyclonal SNAI1 Primary Antibody for WB - ABIN388812 : Barbu, Zhang, Berenstein, Groves, Parks, Siraganian: The transcription factor Zeb2 regulates signaling in mast cells. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)

More Antibodies against Snail Homolog 1 (Drosophila) Interaction Partners

Fruit Fly (Drosophila melanogaster) Snail Homolog 1 (Drosophila) (SNAI1) interaction partners

  1. evidence for mechanosensitivity of cell-cell junctions and implications that myosin-mediated tension can prevent Snail-driven Eepithelial-mesenchymal transitions

  2. Snail can potentiate enhancer activation by collaborating with different activators, providing a new mechanism by which Snail regulates development.

  3. Rapid transcription kinetics and negative autoregulation are responsible for the remarkable homogeneity of snail expression and the coordination of mesoderm invagination.

  4. Study shows that Sna represses transcription of pbl in the mesoderm primordium of D. melanogaster via one or more Sna-binding sites, which are conserved among species of the Drosophila genus, but not in the mosquito, correlating with the different modes of gastrulation in the different genuses.

  5. Complex interactions between cis (show CISH Antibodies)-regulatory modules in native conformation are critical for Drosophila snail expression.

  6. The Snail repressor positions Notch (show NOTCH1 Antibodies) signaling in the Drosophila embryo.

  7. results show that Sna has a positive regulatory function on sim (show SIM2 Antibodies) expression in the presumptive mesectoderm; this positive effect of Sna depends on the Su(H (show RBPJ Antibodies))-binding sites within the sim (show SIM2 Antibodies) promoter, suggesting that Sna regulates Notch (show NOTCH1 Antibodies) signaling

  8. snail is required for Drosophila gastrulation and is not replaceable by Escargot or Worniu.

  9. Dorsal activates twist and snail, and the Dorsal/Twist/Snail network activates and represses other zygotic genes to form the dorsoventral axis in Drosophila.

  10. Snail represses Tom expression in the mesoderm and thereby activates Delta trafficking.

Xenopus laevis Snail Homolog 1 (Drosophila) (SNAI1) interaction partners

  1. The transcription factor Snail1 is essential for tissue separation, enabling paraxial protocadherin (PAPC (show PCDH8 Antibodies)) to promote tissue separation through novel functions.

  2. Interaction with Snail1/2, and Twist function more generally, is regulated by GSK-3-beta (show GSK3b Antibodies)-mediated phosphorylation of conserved sites in the WR domain.

  3. the same E3 ubiquitin ligase (show MUL1 Antibodies) known to regulate Snail family proteins, Partner of paired (Ppa (show FBXL14 Antibodies)), also controlled Twist stability and did so in a manner dependent on the Twist WR-rich domain

Human Snail Homolog 1 (Drosophila) (SNAI1) interaction partners

  1. JianPi JieDu Recipe could inhibit TGF-beta (show TGFB1 Antibodies)-induced epithelial-to-mesenchymal transition in colorectal cancer through TGF-beta (show TGFB1 Antibodies)/Smad (show SMAD1 Antibodies) mediated Snail/E-cadherin (show CDH1 Antibodies) expression

  2. Treatment of these cells with the dual-specificity tyrosine-kinase (show TXK Antibodies) inhibitor lapatinib led to downregulation of epithelial-to-mesenchymal transition as indicated by lower levels of SNAI1 and SNAI2 (show SNAI2 Antibodies) transcripts, integrin AVB6, and matrix metalloproteinase 9 (show MMP9 Antibodies) protein

  3. the present study suggests that GAPDH (show GAPDH Antibodies) plays an important role in cancer metastasis by affecting EMT (show ITK Antibodies) through regulation of Sp1 (show PSG1 Antibodies)-mediated SNAIL expression.

  4. the expression of CCL2 (show CCL2 Antibodies) is significantly correlated with Snail expression and may be used as a predictive co-biomarker for patient prognosis and tumor aggressiveness in gastric cancer.

  5. High Snail1 expression is associated with Recurrence of Prostate Cancer.

  6. Our findings implicate Snail as a target for the prevention of fibrogenesis or fibrosis progression and may offer a means to assess response to therapy.

  7. Snail overexpression induced epithelial-mesenchymal transition and endowed cells with tumor stem cell characteristics.

  8. Upregulation of SNAIL1 promotes prostate cancer.

  9. Snail and N-cadherin (show CDH2 Antibodies) are constitutively and inducibly expressed in papillary thyroid carcinoma

  10. Radixin (show RDX Antibodies) knockdown suppresses the metastasis of SGC (show SGCB Antibodies)-7901 cells in vitro by up-regulation of E-cadherin (show CDH1 Antibodies). The NF-kappaB (show NFKB1 Antibodies)/snail pathway contributes to the regulation of E-cadherin (show CDH1 Antibodies) in response to depletion of radixin (show RDX Antibodies).

Mouse (Murine) Snail Homolog 1 (Drosophila) (SNAI1) interaction partners

  1. Snail1 deficiency modified the phenotype of pancreatic tumors .

  2. miR (show MLXIP Antibodies)-200 promotes the mesenchymal to epithelial transition by suppressing multiple members of the Zeb2 (show ZEB2 Antibodies) and Snail1 transcriptional repressor complexes, such as Smad2 (show SMAD2 Antibodies) and Smad5 (show SMAD5 Antibodies).

  3. show that Snail1-induced fibrosis can be reversed in vivo and that obstructive nephropathy can be therapeutically ameliorated in mice by targeting Snail1 expression

  4. Results suggest that Snai1 is a key factor that triggers ESCs (show NR2E3 Antibodies) exit from the pluripotency state and initiate their differentiation processes.

  5. During embryonic stem cell differentiation, an endogenous Wnt (show WNT2 Antibodies)-mediated burst in Snail1 expression regulates neuroectodermal fate while playing a role in epiblast stem cell exit and the consequent lineage fate decisions that define mesoderm commitment.

  6. The Snail transcription factor regulates the numbers of neural precursor cells and newborn neurons throughout mammalian life.

  7. Snail inhibits adipogenesis through a down-regulation of Nr2f6 (show NR2F6 Antibodies), which in turn facilitates the expression of IL-17 (show IL17A Antibodies), an anti-adipogenic cytokine.

  8. Snail1 acts as a VEGF (show VEGFA Antibodies)-induced regulator of Notch1 (show NOTCH1 Antibodies) signalling and Dll4 (show DLL4 Antibodies) expression. Results document a Snail1-Dll4 (show DLL4 Antibodies)/Notch1 (show NOTCH1 Antibodies) axis that controls embryonic vascular development.

  9. Cav1 (show CAV1 Antibodies) knockout promotes MEK (show MDK Antibodies)-ERK1/2 (show MAPK1/3 Antibodies)-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis.

  10. overexpression of Snail in PDAC cells increased SCF (show KITLG Antibodies) levels, and the media conditioned by Snail-expressing PDAC cells promoted mast cell migration.

Snail Homolog 1 (Drosophila) (SNAI1) Antigen Profile

Protein Summary

The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.

Gene names and symbols associated with SNAI1

  • snail homolog 1 (Drosophila) (SNAI1) antibody
  • snail 1 homolog (LOC100350709) antibody
  • snail 1 homolog (LOC100352102) antibody
  • snail (sna) antibody
  • zinc-finger transcription factor Snail (snail) antibody
  • snail family zinc finger 1 (snai1) antibody
  • snail protein (Snail) antibody
  • transcription factor protein (snail) antibody
  • snail zinc finger protein (snail) antibody
  • snail family zinc finger 1 (SNAI1) antibody
  • snail family zinc finger 1 (Snai1) antibody
  • snail homolog 1 (Drosophila) (Snai1) antibody
  • AI194338 antibody
  • BG:DS01845.1 antibody
  • br28 antibody
  • br29 antibody
  • CG3956 antibody
  • dJ710H13.1 antibody
  • Dmel\\CG3956 antibody
  • l(2)35Db antibody
  • l(2)br28 antibody
  • l(2)br29 antibody
  • l(3)br28 antibody
  • l35Db antibody
  • Sco antibody
  • SLUGH2 antibody
  • sn antibody
  • sna antibody
  • Sna1 antibody
  • SNAH antibody
  • Snai antibody
  • SNAI1 antibody
  • Snail antibody
  • Snail1 antibody
  • xSna antibody
  • Xsnail antibody

Protein level used designations for SNAI1

snail homolog 1 , snail like protein , Protein snail-like protein 1 , snail homolog 1 (Drosophila) , snail 1 homolog , CG3956-PA , scutoid , sna-PA , zinc-finger transcription factor Snail , protein Xsnail , protein snail homolog Sna , protein xSna , snail protein , zinc finger protein with snail domain similar to escargot , transcription factor protein , snail zinc finger protein , snail-like protein 1 , protein sna , protein snail homolog 1 , snail 1 zinc finger protein , snail 1, zinc finger protein , zinc finger protein SNAI1

GENE ID SPECIES
396047 Gallus gallus
702353 Macaca mulatta
745644 Pan troglodytes
100127224 Ovis aries
100350709 Oryctolagus cuniculus
100352102 Oryctolagus cuniculus
34908 Drosophila melanogaster
378469 Strongylocentrotus purpuratus
379615 Xenopus laevis
410464 Apis mellifera
778762 Ciona intestinalis
100303552 Saccoglossus kowalevskii
100029017 Monodelphis domestica
6615 Homo sapiens
116490 Rattus norvegicus
20613 Mus musculus
485924 Canis lupus familiaris
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