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Involved in accumulation of zinc in synaptic vesicles.. Additionally we are shipping Solute Carrier Family 30 (Zinc Transporter), Member 3 Kits (12) and Solute Carrier Family 30 (Zinc Transporter), Member 3 Proteins (3) and many more products for this protein.
Showing 10 out of 33 products:
Rat (Rattus) Polyclonal Slc30a3 Primary Antibody for ICC, IP - ABIN1742413
Maisano, Litvina, Tagliatela, Aaron, Grabel, Naegele: Differentiation and functional incorporation of embryonic stem cell-derived GABAergic interneurons in the dentate gyrus of mice with temporal lobe epilepsy. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2012
Human Polyclonal Slc30a3 Primary Antibody for WB - ABIN574968
Bjorklund, Reese, Sadagoparamanujam, Ghirardi, Woltjer, Taglialatela: Absence of amyloid β oligomers at the postsynapse and regulated synaptic Zn2+ in cognitively intact aged individuals with Alzheimer's disease neuropathology. in Molecular neurodegeneration 2012
Human Polyclonal Slc30a3 Primary Antibody for ICC, IHC - ABIN1742412
Nakahara, Miyake, Tajinda, Ito: Mossy fiber mis-pathfinding and semaphorin reduction in the hippocampus of α-CaMKII hKO mice. in Neuroscience letters 2015
Rat (Rattus) Monoclonal Slc30a3 Primary Antibody for ICC, IP - ABIN1742409
Rafalo, Zadrozna, Nowak, Kotarska, Wiatrowska, Pochwat, Sowa-Kucma, Misztak, Nowak, Szewczyk: The level of the zinc homeostasis regulating proteins in the brain of rats subjected to olfactory bulbectomy model of depression. in Progress in neuro-psychopharmacology & biological psychiatry 2016
ZNT3 and ZNT8 (show SLC30A8 Antibodies) (known to regulate insulin (show INS Antibodies) secretion) have opposite effects on insulin (show INS Antibodies) synthesis and secretion possibly by a transcriptional co-regulation since mRNA expression of ZNT3 was inversely correlated to ZNT8 (show SLC30A8 Antibodies) and ZNT3 over-expression reduced insulin (show INS Antibodies) synthesis and secretion.
An association was found between reduced ZnT3 in the prefrontal cortex and cognitive impairment in patients with either dementia with Lewy bodies or Parkinson's disease dementia.
SNPs in SLC30A3 show a gender-specific association with schizophrenia in an East UK cohort.
The results of this study suggested that ZnT3 protein levels are decreased in the spinal cords of sporadic ALS patients.
AIDL cells exhibited a lower expression of zinc transporter 1 (ZnT1 (show SLC30A1 Antibodies)) and higher expression of ZnT3 than LNCaP cells.
Data show that ZNT3 is extensively present in the Abeta (show APP Antibodies)-positive plaques in the cortex of human AD brains.
SLC30A3 (ZnT3) oligomerization by dityrosine bonds regulates its subcellular localization and metal transport capacity
ZnT3 null mice lack the transporter responsible for stocking synaptic vesicles, although they do have a zinc veneer, albeit diminished compared to wild-type animals.
Dietary or ZnT3-dependent Zn(2+) stores, and intracellular Zn(2+) release from rhodopsin (show RHO Antibodies) recycling are suggested to be involved in light-induced retinal degeneration.
Fundamental changes occur in the expression of proteins and genes important in neurotransmission and are different in the absence of vesicular zinc in ZnT3-deficient knockout mice.
This study demonistrated that zinc transporter-3 regulate the Zinc in brain.
Zinc transporters of the Slc30a/ZnT and Slc39a/Zip families play crucial roles in cell functions, mediating zinc influx to and efflux from the lumen of the secretory pathway, constitutively or in a cell-specific manner. (Review)
Deprivation of oxygen and glucose-SD produced large FluoZin-3 increases that propagated with the event, and signals were abolished in tissues from ZnT3 knockout animals lacking synaptic Zn(2+)
ZnT3 is important for zinc homeostasis modulating presynaptic MAPK (show MAPK1 Antibodies) signaling and is required for hippocampus-dependent memory
Data suggest that expression of zinc homeostatic proteins such as ZnT1 (show SLC30A1 Antibodies) and 3, and metallothioneins 1 and 2, is regulated by crosstalk between synaptic and intracellular pools of Zn(2+).
The results of this study suggested that ZnT3 protein is involved in the Abeta (show APP Antibodies) aggregation in the cerebellum of the AbetaPP/PS1 (show PSEN1 Antibodies) mouse.
Age-dependent loss of transsynaptic Zn(2+) movement leads to cognitive loss, and since extracellular beta-amyloid is aggregated by this pool of Zn(2+), the genetic ablation of ZnT3 may represent a phenocopy for the synaptic and memory deficits of AD.
Involved in accumulation of zinc in synaptic vesicles.
solute carrier family 30 (zinc transporter), member 3
, solute carrier family 30 member 3
, solute carrier family 30 protein
, zinc transporter 3
, zinc transporter ZnT-3