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Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 1 Proteins (SLC7A1)

acts as a cationic amino acid transporter and as an ecotropic retrovirus receptor\; plays a role in the Na+-independent y+ cationic amino acid transport system [RGD, Feb 2006].. Additionally we are shipping Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 1 Antibodies (44) and Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLC7A1 6541 P30825
SLC7A1 11987 Q09143
Rat SLC7A1 SLC7A1 25648 P30823
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Top Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 1 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SLC7A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 1 (SLC7A1) Interaction Partners

Cow (Bovine) Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 1 (SLC7A1) interaction partners

  1. Lipopolysaccharide/tumor necrosis factor-alpha (show TNF Proteins) treatment increased the expression of iNOS (show NOS2 Proteins), arginase II (show ARG2 Proteins), CAT-1, and CAT-2 (show SLC7A2 Proteins) mRNA.

Human Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 1 (SLC7A1) interaction partners

  1. Estradiol increases arginine transport and CAT-1 activity through modulation of constitutive signaling transduction pathways involving ERK. Progesterone inhibits arginine transport and CAT-1 via both PKCalpha and ERK1/2 phosphorylation.

  2. The rs41318021 polymorphism in the SLC7A1 gene was not associated with essential hypertension in 50-year-old subjects.

  3. Overexpression of arginine transporter CAT-1 (show CRAT Proteins) is associated with accumulation of L-arginine (show GATM Proteins) and cell growth in human colorectal cancer tissue.

  4. CAT1, CAT2, and CAT3 localized in adult brains but with uneven distribution.

  5. mRNA levels for high-affini (show CRAT Proteins)ty CAT-1, expressed as a percentage of the wild-type value, are increased by an average 12% an (show DMD Proteins)d 32% in mdx and transgenic mdx:utr mice respectively.

  6. The data demonstrates that CAT1 (show CRAT Proteins) significantly (but most likely not exclusively) contributes to the cellular uptake of asymmetric dimethylarginine.

  7. In hypoxic human pulmonary microvascular endothelial cells, overexpression of CAT-1 (show CRAT Proteins) resulted in significantly greater L-arginine (show GATM Proteins) transport and NO production

  8. In acute congestive heart failure acute renal impairment function and the modulation of metabolism and extracellular transport by the DDAH-1 (show DDAH1 Proteins)/CAT-1 (show CRAT Proteins) system determine high ADMA and SDMA levels after therapy for acute congestive heart failure.

  9. Insulin (show INS Proteins) increased hCATs-L-arginine (show GATM Proteins) transport, maximal transport capacity, and hCAT-1 expression. Sp1 (show PSG1 Proteins) nuclear protein (show RDBP Proteins) abundance and binding to DNA, and SLC7A1 promoter activity was increased by insulin (show INS Proteins).

  10. Data show that the CAT-1 (show CRAT Proteins) isoform plays a role in arginine uptake.

Pig (Porcine) Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 1 (SLC7A1) interaction partners

  1. Arginine supplementation enhances small intestinal expression of SLC7A7 (show Slc7a7 Proteins) and SLC7A1.

  2. Changes in the expression of b(0,+) and CAT-1 in pigs fed on amino acid supplemented versus high proteins diets.

  3. Data show that in minipigs, increased weight and cholesterol resulting from a high-cholesterol diet are correlated with a decrease in the expression of miRNA-122, and that gene expression levels of CAT1 do not differ between groups.

  4. Radiation hybrid mapping data indicate that the porcine SLC7A1 maps to the distal end of the short arm of pig chromosome 11

Mouse (Murine) Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 1 (SLC7A1) interaction partners

  1. TRPV6 (show TRPV6 Proteins) plays an essential role in bone metabolism and is a critical regulator in osteoclasts differentiation and bone resorption.

  2. CAT1 overexpression prevents obesity-induced hypertension by reducing the influence of the SNS (show SCN10A Proteins) on the maintenance of arterial pressure but not by buffering pressor responses to stress.

  3. Adra2a (show ADRA2A Proteins) is expressed in the mesenchyme of the mouse stomach primordium at E11.5. Fzd5 and Trpv6 (show TRPV6 Proteins) are expressed in the epithelial layer of the stomach primordium after E11.5.

  4. Endothelial CAT-1 overexpression can counter the ability of oxidative stress.

  5. focus on TRPV6 (show TRPV6 Proteins) gene polymorphisms, the start of TRPV6 (show TRPV6 Proteins) translation at a non-AUG codon and the functions of TRPV6 (show TRPV6 Proteins) in intestinal Ca(2 (show CA2 Proteins)+) uptake, sperm maturation, and male fertility.

  6. these data indicate that obesity-induced down-regulation of CAT1 expression and subsequent reduced bioavailability of nitric oxide may contribute to the development of obesity-induced hypertension.

  7. Fibroblasts from two long-lived mice mutants (Snell dwarf (show POU1F1 Proteins) and PAPP-A (show PAPPA Proteins) knockout) expressed higher levels of CAT1 (a ATF4 (show ATF4 Proteins) target gene) during stress, suggesting a connection to longevity.

  8. A non-AUG start codon is used in both human and mouse, extending the N-terminus of the protein by 40 amino acids. The increased translation of the smaller TRPV6 (show TRPV6 Proteins) cDNA version may overestimate the in vivo situation where translation efficiency may represent an additional mechanism to tightly control the TRPV6 (show TRPV6 Proteins)-mediated Ca(2 (show CA2 Proteins)+) entry to prevent deleterious Ca(2 (show CA2 Proteins)+) overload.

  9. Augmented endothelial l-arginine (show GATM Proteins) transport attenuated the prohypertensive effects of systemic and renal oxidative stress, suggesting that manipulation of endothelial CAT1 may provide a new therapeutic approach for the treatment of cardiovascular disease.

  10. L-argine transporters CAT-1 and CAT-2A expression and function are significantly increased in Duchenne muscular dystrophy (show DMD Proteins) mice.

Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 1 (SLC7A1) Protein Profile

Protein Summary

acts as a cationic amino acid transporter and as an ecotropic retrovirus receptor\; plays a role in the Na+-independent y+ cationic amino acid transport system

Gene names and symbols associated with SLC7A1

  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 (SLC7A1)
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 (slc7a1)
  • amino acid transporter 1 (AAT1)
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 (Slc7a1)
  • transient receptor potential cation channel, subfamily V, member 6 (Trpv6)
  • 4831426K01Rik protein
  • AI447493 protein
  • amino acid transporter 1 protein
  • Atrc-1 protein
  • Atrc1 protein
  • Cac protein
  • CAT protein
  • Cat-1 protein
  • CaT1 protein
  • CATIONIC AMINO ACID TRANSPORTER 1 protein
  • DKFZp459K194 protein
  • Ecac2 protein
  • ERR protein
  • F7J7.60 protein
  • F7J7_60 protein
  • HCAT1 protein
  • mCAT-1 protein
  • Otrpc3 protein
  • Rec-1 protein
  • REC1L protein
  • Rev-1 protein
  • si:ch211-69k21.2 protein

Protein level used designations for SLC7A1

high affinity cationic amino acid transporter 1 , cationic amino acid transporter 1 , solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 , solute carrier family 7 member 1 , system Y+ basic amino acid transporter , high affinity cationic amino acid transporter 1-like , CAT1 , amino acid transporter, cationic 1 , ecotropic retroviral leukemia receptor homolog , ecotropic retroviral receptor , ecotropic retrovirus receptor homolog , cationic amino acid transporter-1 , CAT-1 , ERR , ecotropic retroviral leukemia receptor , ecotropic retrovirus receptor , Solute carrier family 7 member A1 (amino acid transporter cationic 1) , cationic amino acid transporter, y+ system , cationinc amino acid transporter 1 , solute carrier family 7, member 1 , calcium transport protein 1 , epithelial calcium channel 2 , osmosensitive transient receptor potential channel 3 , transient receptor potential cation channel subfamily V member 6

GENE ID SPECIES
418922 Gallus gallus
452516 Pan troglodytes
486022 Canis lupus familiaris
539465 Bos taurus
559627 Danio rerio
712410 Macaca mulatta
100025569 Monodelphis domestica
100174532 Pongo abelii
100341572 Oryctolagus cuniculus
100407198 Callithrix jacchus
100468558 Ailuropoda melanoleuca
100492323 Xenopus (Silurana) tropicalis
100063073 Equus caballus
100543815 Meleagris gallopavo
100555920 Anolis carolinensis
100593925 Nomascus leucogenys
827860 Arabidopsis thaliana
6541 Homo sapiens
503545 Sus scrofa
11987 Mus musculus
25648 Rattus norvegicus
64177 Mus musculus
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