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Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 Proteins (SLC9A1)

SLC9A1 encodes a Na+/H+ antiporter that is a member of the solute carrier family 9. Additionally we are shipping Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 Antibodies (78) and Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLC9A1 20544 Q61165
SLC9A1 6548 P19634
Rat SLC9A1 SLC9A1 24782 P26431
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Top Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
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Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details

SLC9A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , ,
, ,

More Proteins for Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1) Interaction Partners

Arabidopsis thaliana Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1) interaction partners

  1. Tonoplast-localized NHX1 and NHX2 proteins are essential for active K+ uptake at the tonoplast, for turgor regulation, and for stomatal function.

  2. Overexpression of AtNHX1 gene not only improved salt tolerance but also drought tolerance in transgenic groundnut.

  3. NHX1 and NHX2 mediate K+/H+ exchange to accumulate K+ in the vacuole. NHX1 and NHX2 function together to control cell expansion in vegetative tissues and male reproductive organs and are required for normal flower development.

  4. Studies shoe that the rutin content of the roots, stems and leaves of AtNHX1 transgenic buckwheat increased than those of the control plants.

  5. Use of the T-DNA insertional mutant of AtNHX1 (nhx1 plants) and DNA arrays to assess differences in transcriptional profiles and further characterize the roles of this protein.

  6. the presence of a vacuolar calmodulin-like (show KRIT1 Proteins) protein acting on the vacuolar-localized AtNHX1 C terminus in a Ca(2 (show CA2 Proteins)+)- pH-dependent manner suggests the presence of signaling entities acting within the vacuole.

  7. AtNHX1 has a role in calcium signaling, sulfur metabolism, cell structure and cell growth, as well as vesicular trafficking and protein processing.

  8. To generate salt-tolerant turf and forage, tall fescue (Festuca arundinacea) was transformed with AtNHX1.

Mouse (Murine) Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1) interaction partners

  1. During hypoxia, activation of ROCK enhances NHE1 activity and promotes pulmonary artery smooth muscle cell migration and proliferation.

  2. Na/H exchanger is regulated in dendritic cells by Akt1 (show AKT1 Proteins).

  3. our results suggest that activation of NHE1 induces hypertrophy through the activation of NFAT3 (show NFATC4 Proteins)/Gata4 (show GATA4 Proteins) and OPN (show SPP1 Proteins) expression

  4. NHE1 function is necessary for maintaining mammary branched architecture.

  5. the extracellular matrix (ECM (show MMRN1 Proteins)) composition strongly impacts on NHE1-dependent in vitro cell motility and invasion

  6. long-term ablation of NHE1 activity increases the redox potential, mitigates high-fat diet-induced myocardial stress.

  7. study shows that NHE-1 protein is abundantly expressed in microglial lamellipodia and maintains alkaline pHi in response to BK stimulation

  8. exerts a protective effect by reducing the loss of synaptopodin (show SYNPO Proteins) in podocytes exposed to endoplasmic reticulum stress

  9. NHE1 functions as a metabolic sensor for lipotoxicity.

  10. PDGFRalpha signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1 (show MAP2K1 Proteins)/2-ERK1/2-p90RSK (show RPS6KA1 Proteins) and AKT (show AKT1 Proteins) signaling pathways.

Cow (Bovine) Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1) interaction partners

  1. This study evaluated the role for NHE-1 in diabetic cataract formation and retinal oxidative stress and apoptosis.

  2. Results support the hypothesis that a blood-brain barrier Na/H exchanger, possibly NHE1 and/or NHE2, is stimulated during ischemia to participate in cerebral edema formation.

Pig (Porcine) Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1) interaction partners

  1. NHE isoform switching and KChIP2 (show KCNIP2 Proteins) upregulation takes place in aging porcine atria.

  2. NHE-1 inhibitor cariporide attenuates skeletal muscle infarction when administered before ischemia or reperfusion.

Human Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1) interaction partners

  1. Human NHE1 acts as an ERK2 (show MAPK1 Proteins) membrane protein scaffold in vivo that is necessary for ERK2 (show MAPK1 Proteins) activation via direct interactions, and loss of scaffolding by NHE1 leads to decreased ERK2 (show MAPK1 Proteins) activation.

  2. interaction of NHE1, NCX1 (show SLC8A1 Proteins) and CaM (show CALM1 Proteins) mediates the effects of IL6 (show IL6 Proteins) on human hepatocellular carcinoma

  3. the present study revealed that miR (show MLXIP Proteins)-27b is upregulated by HPV16 E7 to inhibit PPARg (show PPARG Proteins) expression and promotes proliferation and invasion in cervical carcinoma cells.

  4. The NHE-1 is a ubiquitously expressed cell membrane protein which regulates intracellular pH (pH(i)) and extracellular pH (pH(e)) homeostasis and cell volume.

  5. Functional studies of N266H mutation in SLC9A1 gene showed a minor effect on the level of expression and no effect on targeting of the protein, however there was a complete absence of SLC9A1 activity.

  6. PKC-delta (show PKCd Proteins) activates p38/MAPK (show MAPK14 Proteins), responsible for the inhibition of MMP-2 (show MMP2 Proteins) and -9 secretion, PKC-epsilon (show PRKCE Proteins) activates a pathway made of ERK1/2, mTOR (show FRAP1 Proteins) and S6K (show RPS6KB1 Proteins) responsible for the inhibition of NHE1 activity and cell migration.

  7. Data suggest that Na/H exchanger isoform one (NHE1) is critical in triple-negative breast cancer metastasis.

  8. Importantly, the specific NHE1 inhibitor cariporide reduced both three-dimensional growth and invasion independently of PDAC subtype and synergistically sensitized these behaviors to low doses of erlotinib.

  9. Concurrent speed endurance and resistance training increases skeletal muscle NHE1 activity.

  10. Mutation of SLC9A1 is associated with ataxia (show USP14 Proteins)-deafness Lichtenstein-Knorr syndrome.

Rabbit Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1) interaction partners

  1. In vitro phosphorylation of NHE1 C-terminal fusion proteins determined that ERK (show MAPK1 Proteins)-dependent phosphorylation of the cytoplasmic region was not dependent on Ser (show SIGLEC1 Proteins)(703); however, phosphorylation by p90(rsk (show RPS6KA1 Proteins)) required Ser (show SIGLEC1 Proteins)(703).

Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1) Protein Profile

Protein Summary

This gene encodes a Na+/H+ antiporter that is a member of the solute carrier family 9. The encoded protein is a plasma membrane transporter that is expressed in the kidney and intestine. This protein plays a central role in regulating pH homeostasis, cell migration and cell volume. This protein may also be involved in tumor growth.

Gene names and symbols associated with SLC9A1

  • sodium/hydrogen exchanger 1 (NHX1)
  • solute carrier family 9 (sodium/hydrogen exchanger), member 1 (Slc9a1)
  • solute carrier family 9 (sodium/hydrogen exchanger), member 1 (SLC9A1)
  • solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 (SLC9A1)
  • solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 (Slc9a1)
  • APNH protein
  • AT-NHX1 protein
  • ATNHX protein
  • ATNHX1 protein
  • AW554487 protein
  • NA(+)/H(+) ANTIPORTER protein
  • Na+/H+ exchanger 1 protein
  • NHE-1 protein
  • NHE1 protein
  • swe protein
  • T21B4.60 protein
  • T21B4_60 protein

Protein level used designations for SLC9A1

NHE-1 , Na(+)/H(+) exchanger 1 , Na+/H+ antiporter , Na+/H+, amiloride sensitive , slow-wave epilepsy , sodium/hydrogen exchanger 1 , solute carrier family 9 member 1 , solute carrier family 9, member 1 , sodium proton exchanger , solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride sensitive) , solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive) , Solute carrier family 9 member 1 , NA(+)-H+ exchanger protein , Na-Li countertransporter , Solute carrier family 9 (sodium/hydrogen exchanger 1), antiporter, Na+/H+, (amiloride sensitive) , solute carrier family 9 (sodium/hydrogen exchanger), member 1 , Na+/H+ exchanger , pH regulatory protein (Na(+) /H(+) exchanger)

GENE ID SPECIES
832773 Arabidopsis thaliana
20544 Mus musculus
317654 Bos taurus
100689320 Cricetulus griseus
397458 Sus scrofa
6548 Homo sapiens
24782 Rattus norvegicus
419580 Gallus gallus
478171 Canis lupus familiaris
100009586 Oryctolagus cuniculus
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