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SLC9A9 encodes a sodium/proton exchanger that is a member of the solute carrier 9 protein family. Additionally we are shipping Solute Carrier Family 9, Subfamily A (NHE9, Cation Proton Antiporter 9), Member 9 Antibodies (65) and many more products for this protein.
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SLC9A9 has an oncogenic function by being related to EGFR (show EGFR Proteins) signaling, suggesting SLC9A9 may be a novel prognostic indicator and a therapeutic target in colorectal cancer
Ectopic expression of NHE9 in human brain microvascular endothelial cells without external cues induced up-regulation of the transferrin receptor (TfR) and down-regulation of ferritin (show FTL Proteins), leading to an increase in iron uptake
Taken together, our findings demonstrate that NHE9 can be an effective predictor of chemoradiotherapy response in esophageal squamous cell carcinoma
the expression of SLC9A9 can be a prognostic predictor for ESCC.
SLC9A9 appears to influence the differentiation of T cells to a proinflammatory fate and may have a broader role in multiple sclerosis disease activity. There is an association between rs9828519(G) and nonresponse to IFNbeta treatment.
find interesting gene expression changes in endosomal NHE6 (show SLC9A6 Proteins) and NHE9 in postmortem autism brains.
Loss-of-function mutations in NHE9 may contribute to autistic phenotype by modulating synaptic membrane protein expression and neurotransmitter clearance.
33 directly measured and 13 derived glycosylation traits in 3533 individuals were identified and three novel gene association (MGAT5 (show MGAT5 Proteins), B3GAT1 (show B3GAT1 Proteins) and SLC9A9) were identified using an additional European cohort.
SLC9A9 is a target gene of the BACH1 (show BACH1 Proteins) transcription factor according to ChIP-seq analysis in HEK (show EPHA3 Proteins) 293 cells.
This review defines NHE6-9 as organellar NHEs that are fairly dynamic, implying that they are subjected to intracellular trafficking and thus they continuously shuttle between organelles and the plasma membrane.
This is the first animal behavior study that links Slc9a9 to Autism spectrum disorders.
NHE9/Slc9a9 is expressed in the inner ear
This gene encodes a sodium/proton exchanger that is a member of the solute carrier 9 protein family. The encoded protein localizes the to the late recycling endosomes and may play an important role in maintaining cation homeostasis. Mutations in this gene are associated with autism susceptibility 16 and attention-deficit/hyperactivity disorder.
Na(+)/H(+) exchanger 9
, putative protein product of Nbla00118
, sodium/hydrogen exchanger 9
, sodium/proton exchanger NHE9
, solute carrier family 9 (sodium/hydrogen exchanger)
, solute carrier family 9 member 9
, solute carrier family 9 (sodium/hydrogen exchanger), member 9
, sodium/hydrogen exchanger 9-like