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Sorbin and SH3 Domain Containing 1 Proteins (SORBS1)

Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Additionally we are shipping SORBS1 Antibodies (80) and SORBS1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SORBS1 10580 Q9BX66
SORBS1 20411 Q62417
Rat SORBS1 SORBS1 686098  
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Top SORBS1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SORBS1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for Sorbin and SH3 Domain Containing 1 (SORBS1) Interaction Partners

Human Sorbin and SH3 Domain Containing 1 (SORBS1) interaction partners

  1. data suggest that SORBS1 might be a gene involved in diabetic nephropathy.

  2. Our NMR and ITC data indicate that the SH3a and SH3b domains of CAP simultaneously bind to a long proline-rich region of vinculin (show VCL Proteins) with different binding specificities

  3. Sequestration of the ponsin splice variant R85FL by the polyglutamine-expanded Atx7 in cell is mediated by the specific SH3C-PRR (show PVRL1 Proteins) interaction, which is implicated in the pathogenesis of spinocerebellar ataxia (show USP14 Proteins) 7.

  4. a novel signaling network containing FRS2 (show FRS2 Proteins), CAP and flotillin-1 (show FLOT1 Proteins)

  5. The novel ponsin isoform and its interaction with Nck1 (show NCK1 Proteins)/2 provide exciting insight into the convergence of signalling pathways at the costameres, and its crucial role for skeletal muscle differentiation and re-generation.

  6. preliminary results indicate the depot-specific differential expression of sorbin and SH3 domain-containing-1(SORBS1) in relation to body mass index

  7. SORBS1 polymorphism does not play a major role in premature pubarche, hyperandrogenism, and/or polycystic ovary syndrome in children and adolescent girls.

  8. Soluble intracellular domain of teneurin-1 (show ODZ1 Proteins) binds to the cell membrane enriched in CAP/ponsin

  9. analysis of paxillin (show PXN Proteins) and ponsin interaction in nascent costameres of muscle cells

  10. AA genotype of SORBS1 T228A polymorphism may play a role in lacunar infarction in the Japanese population.

Mouse (Murine) Sorbin and SH3 Domain Containing 1 (SORBS1) interaction partners

  1. The study screened CrkL (show CRKL Proteins) binding proteins using RNA interference (RNAi) and identified Sorbs1 and Sorbs2 (show Sorbs2 Proteins) as two proteins that are enriched at AChR clusters and are required for the formation of AChR aggregation in vitro.

  2. Suggest a novel modulatory role for CAP in the heart as a key protein stabilizing antiviral type I interferon (show IFNA Proteins) production, while protecting from excessive cytotoxic responses in CVB3 mediated endocarditis.

  3. Low- and high-dose ursolic acid can improve the glycometabolism and differentiation of 3T3-L1 adipocytes with insulin (show INS Proteins) resistance by up-regulating the expression of CAP.

  4. a novel signaling network containing FRS2 (show FRS2 Proteins), CAP and flotillin-1 (show FLOT1 Proteins)

  5. The novel ponsin isoform and its interaction with Nck1 (show NCK1 Proteins)/2 provide exciting insight into the convergence of signalling pathways at the costameres, and its crucial role for skeletal muscle differentiation and re-generation.

  6. CAP, Cbl (show CBL Proteins) iso-forms, and CrkII (show CRK Proteins) are not required components of insulin (show INS Proteins) signaling to GLUT4 (show SLC2A4 Proteins) transporters

  7. Bone marrow-specific Sorbs1 (Cap) gene deletion protects against high-fat diet-induced insulin (show INS Proteins) resistance.

  8. These data provide a mechanism for the lipid raft localization of TrkA (show NTRK1 Proteins) and establish the importance of the CAP adaptor protein for nerve growth factor activation of the extracellular signal-regulated kinase and neuronal differentiation.

SORBS1 Protein Profile

Protein Summary

Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin- stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions.

Gene names and symbols associated with SORBS1

  • sorbin and SH3 domain containing 1 (SORBS1)
  • sorbin and SH3 domain containing 1 (Sorbs1)
  • 2310065E01Rik protein
  • 9530001P15Rik protein
  • CAP protein
  • FLAF2 protein
  • mKIAA1296 protein
  • R85FL protein
  • Sh3d5 protein
  • SH3P12 protein
  • SORB1 protein

Protein level used designations for SORBS1

Fas-ligand associated factor 2 , SH3 domain protein 5 , SH3-domain protein 5 (ponsin) , c-Cbl associated protein , c-Cbl-associated protein , ponsin , sorbin and SH3 domain-containing protein 1

GENE ID SPECIES
10580 Homo sapiens
20411 Mus musculus
686098 Rattus norvegicus
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