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SNX18 encodes a member of the sorting nexin family. Additionally we are shipping SNX18 Proteins (4) and many more products for this protein.
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SNX18 promotes autophagosome formation by virtue of its ability to remodel membranes and provide membrane to forming autophagosomes.
The sorting nexin 9 (SNX9 (show SNX9 Antibodies)) subfamily members - SNX9 (show SNX9 Antibodies), SNX18 and SNX33 - are required for progression and completion of mitosis.
FIP5-SNX18 complex plays a pivotal role in the polarized transport of apical proteins during apical lumen initiation in epithelial cells.
The results indicate that SNX9 (show SNX9 Antibodies)-family members make up discrete membrane-scission units together with dynamin (show DNM1 Antibodies), and suggest that SNX18 mediates budding of carriers for AP-1 (show FOSB Antibodies)-positive endosomal trafficking.
SNX18 may play an active role in axonal elongation
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. Multiple transcript variants encoding different isoforms have been found for this gene.
sorting nexin 18
, sorting nexin associated golgi protein 1
, sorting nexin-18
, sorting nexin-18-like
, SH3 and PX domain-containing protein 3B
, sorting nexin-associated Golgi protein 1