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anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) Antibodies

The protein encoded by S1PR1 is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. Additionally we are shipping S1PR1 Kits (22) and S1PR1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
S1PR1 1901 P21453
S1PR1 13609 O08530
S1PR1 29733 P48303
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Top anti-S1PR1 Antibodies at antibodies-online.com

Showing 10 out of 187 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated EIA, IHC (p) 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of hEDG1-I25 (ABIN390082) in mouse lung tissue lysates (35 µg/lane). EDG1 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of S1P1 in Mouse thymus tissue with EDG-1 / S1PR1 antibody at 5 μg/ml. Western blot analysis of S1P1 in Mouse thymus lysate with EDG-1 / S1PR1 antibody at 1 µg/ml (A) and 2 μg/ml (B). 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse PE FACS Detection of S1P1/EDG-1 in CHO Chinese Hamster Cell Line Transfected with Human S1P1/EDG-1 and eGFP by Flow Cytometry. CHO Chinese hamster ovary cell line transfected with either (A) human S1P1/EDG-1 or (B) irrelevant transfectants and eGFP were stained with Mouse Anti-Human S1P1/EDG-1 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$387.19
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$665.50
Details
Human Mouse Un-conjugated FACS Detection of S1P1/EDG-1 in CHO Chinese Hamster Cell Line Transfected with Human S1P1/EDG-1 and eGFP by Flow Cytometry. CHO Chinese hamster ovary cell line transfected with either (A) human S1P1/EDG-1 or (B) irrelevant transfectants and eGFP were stained with Mouse Anti-Human S1P1/EDG-1 Monoclonal Antibody. 100 μg Log in to see 6 to 7 Days
$367.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Western Blot: S1P1/EDG-1 Antibody [ABIN43518314] - Analysis of S1P1 from transfected HEK293 cell lysate. Immunocytochemistry/Immunofluorescence: S1P1/EDG-1 Antibody [ABIN43518314] - Transfected CCL39 cells 0.1 mg Log in to see 5 to 7 Days
$408.19
Details
Mouse Rat Allophycocyanin FACS Detection of S1P1/EDG-1 in HEK293 Human Cell Line Transfected with S1P1/EDG-1 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with S1P1/EDG-1 and eGFP was stained with either (A) Rat Anti-Mouse S1P1/EDG-1 APC-conjugated Monoclonal Antibody. Detection of S1P1/EDG-1 in Mouse Thymocytes by Flow Cytometry. Mouse thymocytes were stained with Rat Anti-Mouse CD4 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$433.13
Details
Zebrafish Rabbit Un-conjugated WB DANREs1pr1 Antibody (C-term) (ABIN1881771) western blot analysis in zebra fish brain tissue lysates (35 µg/lane). This demonstrates the DANREs1pr1 antibody detected the DANREs1pr1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details

S1PR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-S1PR1 Antibodies

  1. Human Polyclonal S1PR1 Primary Antibody for WB - ABIN264982 : Liu, Wada, Yamashita, Mi, Deng, Hobson, Rosenfeldt, Nava, Chae, Lee, Liu, Hla, Spiegel, Proia: Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. in The Journal of clinical investigation 2000 (PubMed)
    Show all 9 references for ABIN264982

  2. Human Polyclonal S1PR1 Primary Antibody for EIA, IHC (p) - ABIN358616 : Dorsam, Graeler, Seroogy, Kong, Voice, Goetzl: Transduction of multiple effects of sphingosine 1-phosphate (S1P) on T cell functions by the S1P1 G protein-coupled receptor. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 5 references for ABIN358616

  3. Human Monoclonal S1PR1 Primary Antibody for FACS - ABIN4899114 : Williams, Stilhano, To, Tran, Wong, Silva: Hypoxia augments outgrowth endothelial cell (OEC) sprouting and directed migration in response to sphingosine-1-phosphate (S1P). in PLoS ONE 2015 (PubMed)
    Show all 4 references for ABIN4899114

  4. Human Polyclonal S1PR1 Primary Antibody for EIA, IHC (p) - ABIN500650 : Miyasaka, Tanaka: Lymphocyte trafficking across high endothelial venules: dogmas and enigmas. in Nature reviews. Immunology 2004 (PubMed)
    Show all 4 references for ABIN500650

  5. Mouse (Murine) Monoclonal S1PR1 Primary Antibody for FACS - ABIN4898837 : Cuenca, Romero, Sintes, Terhorst, Engel: Targeting of Ly9 (CD229) Disrupts Marginal Zone and B1 B Cell Homeostasis and Antibody Responses. in Journal of immunology (Baltimore, Md. : 1950) 2016 (PubMed)
    Show all 3 references for ABIN4898837

  6. Zebrafish (Danio rerio) Polyclonal S1PR1 Primary Antibody for WB - ABIN1881771 : Im, Ungar, Lynch: Characterization of a zebrafish (Danio rerio) sphingosine 1-phosphate receptor expressed in the embryonic brain. in Biochemical and biophysical research communications 2000 (PubMed)

  7. Human Polyclonal S1PR1 Primary Antibody for ICC, IF - ABIN4351831 : Awojoodu, Ogle, Sefcik, Bowers, Martin, Brayman, Lynch, Peirce-Cottler, Botchwey: Sphingosine 1-phosphate receptor 3 regulates recruitment of anti-inflammatory monocytes to microvessels during implant arteriogenesis. in Proceedings of the National Academy of Sciences of the United States of America 2013 (PubMed)

  8. Human Monoclonal S1PR1 Primary Antibody for FACS - ABIN4895626 : Llinàs, Lázaro, de Salort, Matesanz-Isabel, Sintes, Engel: Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry. in Immunology letters 2010 (PubMed)

More Antibodies against S1PR1 Interaction Partners

Human Sphingosine-1-Phosphate Receptor 1 (S1PR1) interaction partners

  1. S1PR1 inhibits the apoptosis of human myeloid leukemia (show BCL11A Antibodies) cells and promotes their proliferation.

  2. These results suggest that S1P (show MBTPS1 Antibodies) signaling plays a role in cell proliferation and drug resistance in multiple myeloma, and targeting this pathway will provide a new therapeutic direction for multiple myelomamanagement.

  3. Sphingosine 1-phosphate-induced IL-8 (show IL8 Antibodies) gene expression is mainly regulated via S1PR(1), and its secretion is regulated through S1PR(2 (show S1PR2 Antibodies)) receptor subtype.

  4. multiple lines of evidence demonstrate that S1PR1 signaling sets the sensitivity of pDC (show PNKD Antibodies) amplification of IFN responses, thereby blunting pathogenic immune responses

  5. The results indicate that sphingosine 1-phosphate is involved in the migration of precursor T-cell lymphoblastic leukemia-lymphoma blasts in vitro, which is dependent on S1P1 expression.

  6. Overexpression of miR148a or inhibition of S1PR1 suppressed SKOV3 cell migration and invasion, while restoration of S1PR1 expression reversed the suppressive effect of miR148a upregulation on SKOV3 cell migration and invasion.

  7. the ability of ApoM (show APOM Antibodies)(+)HDL (show HSD11B1 Antibodies) to act as a biased agonist on S1P1 inhibits vascular inflammation, which may partially explain the cardiovascular protective functions of HDL (show HSD11B1 Antibodies).

  8. S1P (show MBTPS1 Antibodies) receptor modulation reduces leukocyte migration across the endothelial barrier

  9. SGPL1 (show SGPL1 Antibodies) ratio correlated with increased cellular sphingosine-1-phosphate (S1P (show MBTPS1 Antibodies)), and S1P (show MBTPS1 Antibodies) correlated with drug resistance (IC50).

  10. Within lymphoid follicles, the S1P1 distribution pattern is complementary to that of CCR7 (show CCR7 Antibodies)/CXCR4 (show CXCR4 Antibodies), with strong immunoreactivity tightly restricted to mantle zone B cells. This may play a role in B-cell migration toward the S1p (show MBTPS1 Antibodies)-enriched follicle center.

Mouse (Murine) Sphingosine-1-Phosphate Receptor 1 (S1PR1) interaction partners

  1. S1P induced chemotaxis in M1 macrophages and changed cytokine production in M2 macrophages. Phagocytosis was not affected by S1P-signalling.

  2. Data indicate that forkhead box F1 (Foxf1 (show FOXF1 Antibodies)) deletion from endothelial cells decreases the abundance of sphingosine 1-phosphate receptor 1 (S1PR1).

  3. Study provided evidence for a role of S1P1 in regulating oligodendrocyte differentiation and developmental myelination

  4. Galphas (show GNAS Antibodies) depletion blocks the S1PR1-activation induced VE-cadherin (show CDH5 Antibodies) stabilization at junctions.

  5. S1P is localized in the presynaptic regions of mature neurons and is regulated by sphingosine-1-phosphate.

  6. S1P1 receptor-selective up-regulation reduces the severity of acute graft versus host disease by inhibiting macrophage recruitment.

  7. Early after VSV infection, WT and S1PR1(-/-) effector T cells localized exclusively within the lymph node paracortex. However, in contrast to WT, S1PR1(-/-) effector T cells failed to enter the sinuses.

  8. GPER (show GPER Antibodies) and Gankyrin (show PSMD10 Antibodies) might be implicated in the hormonal regulation of endometriosis and be associated with the severity of endometriosis.

  9. Sphingosine-1-Phosphate Receptor-1 Selective Agonist Enhances Collateral Growth and Protects against Subsequent Stroke.

  10. the ability of ApoM (show APOM Antibodies)(+)HDL (show HSD11B1 Antibodies) to act as a biased agonist on S1P1 inhibits vascular inflammation, which may partially explain the cardiovascular protective functions of HDL (show HSD11B1 Antibodies).

Cow (Bovine) Sphingosine-1-Phosphate Receptor 1 (S1PR1) interaction partners

  1. Polymorphisms in promoter regions of PDHB (show PDHB Antibodies), SORBS1 (show SORBS1 Antibodies), and EDG1 genes showing marbling-associated expression changes.

  2. we detected 2 novel SNPs, referred to as g.1475435G>A and g.1471620G>T, in the 5' flanking region of the EDG1 between low-marbled and high-marbled steer groups

  3. EDG1 SNPs, although they may not be regarded as a causal mutation, may be useful for effective marker-assisted selection to increase the levels of marbling in Japanese Black beef cattle.

S1PR1 Antigen Profile

Protein Summary

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion.

Gene names and symbols associated with S1PR1

  • sphingosine-1-phosphate receptor 5a (s1pr5a) antibody
  • sphingosine-1-phosphate receptor 1 (S1PR1) antibody
  • sphingosine-1-phosphate receptor 1 (S1pr1) antibody
  • AI849002 antibody
  • CD363 antibody
  • CHEDG1 antibody
  • D1S3362 antibody
  • ECGF1 antibody
  • EDG-1 antibody
  • Edg1 antibody
  • fd11a07 antibody
  • Lpb1 antibody
  • S1p antibody
  • S1p1 antibody
  • wu:fd11a07 antibody
  • zgc:92296 antibody

Protein level used designations for S1PR1

sphingosine-1-phosphate receptor 1 , sphingosine 1-phosphate receptor 1 , endothelial differentiation, sphingolipid G-protein-coupled receptor, 1 , S1P receptor 1 , S1P receptor Edg-1 , endothelial differentiation G-protein coupled receptor 1 , sphingosine 1-phosphate receptor EDG1 , sphingosine 1-phosphate receptor Edg-1 , endothelial differentiation sphingolipid G-protein-coupled receptor 1 , lysophospholipid receptor B1 , EDG1 (Edg1) , S1P1

GENE ID SPECIES
492350 Danio rerio
100174622 Pongo abelii
424462 Gallus gallus
457063 Pan troglodytes
490138 Canis lupus familiaris
716813 Macaca mulatta
100050049 Equus caballus
1901 Homo sapiens
13609 Mus musculus
29733 Rattus norvegicus
281135 Bos taurus
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