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May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity).. Additionally we are shipping Spindlin 1 Antibodies (29) and Spindlin 1 Proteins (8) and many more products for this protein.
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High SPIN1 expression is associated with liposarcoma.
Spindlin1 activates Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling downstream from protein arginine methyltransferase 2 (PRMT2 (show PRMT2 ELISA Kits)) and the MLL (show MLL ELISA Kits) complex, which together are capable of generating a specific H3 "K4me3-R8me2a" pattern.
the histone sequence is recognized in a distinct manner involving the amino terminus and a pair of arginine residues of histone H3 (show HIST3H3 ELISA Kits), and disruption of the binding impaired stimulation of pre-RNA expression by Spindlin1
SPINDLIN1, which may be a novel substrate of the Aurora-A kinase (show AURKA ELISA Kits), promotes cancer cell growth through WNT (show WNT2 ELISA Kits)/TCF-4 (show TCF4 ELISA Kits) signaling activation.
Spin1 regulates maternal transcripts post-transcriptionally and is involved in meiotic resumption
Spin1 isoform2 is a protein expressed highly in adult testis, which might be involved in spermatogenesis and could be necessary for normal sperm motility
May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity).
spindlin family, member 3
, spindlin 1
, ovarian cancer-related protein
, 30000 Mr metaphase complex
, SSEC P