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anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) Antibodies

SPI1 encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. Additionally we are shipping Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 Proteins (9) and Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SPI1 435318  
SPI1 299282  
SPI1 6688 P17947
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Top anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 Antibodies at antibodies-online.com

Showing 10 out of 130 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-SPI1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:6... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated ELISA, WB ABIN334471 (0.03µg/ml) staining of DAUDI lysate (35µg protein in RIPA ... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis in WiDr cell line lysates (35ug/lane) using SPI1... 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from COS7 cells, using SPI1 Antibody... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated FACS, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green... Figure 2: Flow cytometric analysis of HeLa cells using SPI1 mouse mAb ... 100 μL Log in to see 3 to 4 Days
$544.89
Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: Sfpi1  Sample Tissue: Mouse Testis lysates ... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p) 7 mL Log in to see 2 to 3 Days
$354.00
Details

SPI1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , , , ,
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Rat (Rattus) , ,
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Human , , , ,
, , ,

Top referenced anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 Antibodies

  1. Human Polyclonal SPI1 Primary Antibody for EIA, WB - ABIN954927 : Rimmelé, Komatsu, Hupé, Roulin, Barillot, Dutreix, Conseiller, Bensimon, Moreau-Gachelin, Guillouf: Spi-1/PU.1 oncogene accelerates DNA replication fork elongation and promotes genetic instability in the absence of DNA breakage. in Cancer research 2010 (PubMed)
    Show all 3 references for ABIN954927

  2. Human Polyclonal SPI1 Primary Antibody for EIA, WB - ABIN375231 : Uvarov, Ludwig, Markkanen, Rivera, Airaksinen: Upregulation of the neuron-specific K+/Cl- cotransporter expression by transcription factor early growth response 4. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)

  3. Human Monoclonal SPI1 Primary Antibody for FACS, ELISA - ABIN3072909 : Xu, Wang, Wang, Wu, Zhao, Zhu, Qiu, Xue, Shao, Guo, Li: PU.1 can regulate the ZNF300 promoter in APL-derived promyelocytes HL-60. in Leukemia research 2010 (PubMed)

  4. Chicken Polyclonal SPI1 Primary Antibody for WB - ABIN2780474 : Crotti, Sharma, Fleming, Flannery, Ostrowski, Goldring, McHugh: PU.1 and NFATc1 mediate osteoclastic induction of the mouse beta3 integrin promoter. in Journal of cellular physiology 2008 (PubMed)

  5. Human Polyclonal SPI1 Primary Antibody for ELISA, WB - ABIN1533640 : Ray, Culine, Tavitain, Moreau-Gachelin: The human homologue of the putative proto-oncogene Spi-1: characterization and expression in tumors. in Oncogene 1990 (PubMed)

  6. Chicken Polyclonal SPI1 Primary Antibody for WB - ABIN2777287 : Lin, Rikihisa: Ehrlichia chaffeensis downregulates surface Toll-like receptors 2/4, CD14 and transcription factors PU.1 and inhibits lipopolysaccharide activation of NF-kappa B, ERK 1/2 and p38 MAPK in host monocytes. in Cellular microbiology 2004 (PubMed)

  7. Chicken Polyclonal SPI1 Primary Antibody for WB - ABIN2780304 : McDevit, Nikolajczyk: Changes in immunoglobulin-nucleoprotein complex structure mapped by chromatin immunoprecipitation. in Molecular immunology 2006 (PubMed)

More Antibodies against Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 Interaction Partners

Mouse (Murine) Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) interaction partners

  1. findings suggest that Gata1 (show GATA1 Antibodies) & PU.1 transcription factors are only executing and reinforcing lineage choice once made. These results challenge the current prevailing model of early myeloid lineage choice

  2. involved in osteoclast development by transactivating NFATc1 (show NFATC1 Antibodies) expression via direct binding to the NFATc1 (show NFATC1 Antibodies) promoter

  3. GATA1 (show GATA1 Antibodies) and PU.1 bind in vitro and in vivo the proximal promoter region of the RPS19 (show RPS19 Antibodies) gene which is frequently mutated in Diamond-Blackfan Anemia.

  4. PU.1 Suppresses Th2 Cytokine Expression via Silencing of GATA3 (show GATA3 Antibodies) Transcription in Dendritic Cells

  5. Taken together, our results suggest that the expression of NDRG2 (show NDRG2 Antibodies) potentially inhibits osteoclast differentiation and plays a role in modulating the signal transduction pathway responsible for osteoclastogenesis.

  6. Our results suggest that complementary biological functions of PU.1 and Spi-B (show SPIB Antibodies) may be explained by their interaction with a similar set of regions in the genome of B cells.

  7. PU.1 keeps macrophage-specific genes accessible during differentiation by preventing Polycomb (show CBX2 Antibodies) repressive complex 2 binding to transcriptional regulatory elements.

  8. Nfkb1 (show NFKB1 Antibodies) transcriptional activation by PU.1 and Spi-B (show SPIB Antibodies) promotes toll (show TLR4 Antibodies)-like receptor-mediated B cell proliferation.

  9. These findings indicate that PU.1-mediated upregulation of CSF-1R (show CSF1R Antibodies) is a critical effector of MLL (show MLL Antibodies) leukemogenesis.

  10. The Nogo-B (show RTN4 Antibodies)-PirB (show LILRB3 Antibodies) axis controls macrophage-mediated vascular remodeling.

Human Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) interaction partners

  1. This study showed that HCV infection might abrogate NK cytotoxic potential through altering PU.1, NKG2D (show KLRK1 Antibodies) receptor and perforin (show PRF1 Antibodies) molecules.

  2. SPI1-GFI1B (show GFI1B Antibodies) transcriptional network is an important regulatory axis in acute myeloid leukemia (show BCL11A Antibodies) as well as in the development of erythroid versus myelomonocytic cell fate

  3. The GATA-1-mediated inhibition of PU.1 gene transcription in human AML-erythroleukemias mediated through the URE represents important mechanism that contributes to PU.1 downregulation and leukemogenesis that is sensitive to DNA demethylation therapy

  4. PU.1 downregulation was noted in B-CLL/SLL (show SLC35B2 Antibodies) samples positive for the adverse prognostic markers CD38 and ZAP-70 (show ZAP70 Antibodies).

  5. This study demonstrated positive regulation of monocyte/macrophage differentiation by lnc-MC and uncovered an elaborate regulation mechanism composed of PU.1, lnc-MC, miR (show MLXIP Antibodies)-199a-5p, and ACVR1B (show ACVR1B Antibodies).

  6. Collectively, IMiDs exert demethylation activity through inhibiting DNMT1 (show DNMT1 Antibodies), 3a, and 3b, and up-regulating PU.1 expression, which may be one of the mechanisms of the anti-myeloma activity of IMiDs.

  7. PU.1 suppressive target gene, metallothionein 1G (show MT1G Antibodies), inhibits retinoic acid-induced NB4 cell differentiation.

  8. A novel network has been described in acute myeloid leukemia (show BCL11A Antibodies) in which FLT3 (show FLT3 Antibodies)-ITD signaling induces oncogenic miR (show MLXIP Antibodies)-155 by p65 (show GORASP1 Antibodies) and STAT5 (show STAT5A Antibodies) thereby targeting transcription factor PU.1.

  9. The increased CITED2 expression in acute myeloid leukemia results in better hematopoietic stem cell survival, lower PU.1 levels, and perturbed myeloid differentiation program that contributes to leukemia persistence.

  10. PU.1- targeted genes undergo Tet2 (show TET2 Antibodies)-coupled demethylation and DNMT3b (show DNMT3B Antibodies)-mediated methylation in monocyte-to-osteoclast differentiation.

Pig (Porcine) Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) interaction partners

Zebrafish Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) interaction partners

  1. eaf1 (show EAF1 Antibodies) has a role in suppressing foxo3b expression to modulate transcriptional activity of gata1 (show GATA1 Antibodies) and spi1 in primitive hematopoiesis

  2. Our results indicate that Kzp (show ANPEP Antibodies) is a critical transcriptional factor for the expression of gata2 and pu.1 to modulate primitive hematopoiesis.

  3. Runx1 (show RUNX1 Antibodies) is induced by high Pu.1 level and in turn transrepresses pu.1 expression, thus constituting a negative feedback loop that fashions a favorable Pu.1 level required for balanced fate commitment to neutrophils versus macrophages.

  4. The authors show that tif1gamma (show TRIM33 Antibodies) modulates the erythroid versus myeloid fate outcomes from HSCs by differentially controlling the levels of gata1 (show GATA1 Antibodies) and pu.1.

  5. found a gene group downregulated on spi1 knockdown,containing all 5 previously identified Spi1-dependent genes as well as a large set of novel immune-related genes

  6. In zebrafish, spi1 marks a rostral population of LPM cells committed to a myeloid fate anatomically separated from and developmentally independent of erythroid commitment in the caudal (show CAD Antibodies) LPM.

Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) Antigen Profile

Protein Summary

This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SPI1

  • serine (or cysteine) peptidase inhibitor, clade A, member 3D, pseudogene (Serpina3d-ps) antibody
  • Serine protease inhibitor (LOC299282) antibody
  • spleen focus forming virus (SFFV) proviral integration oncogene (SPI1) antibody
  • spleen focus forming virus (SFFV) proviral integration oncogene (Spi1) antibody
  • spleen focus forming virus (SFFV) proviral integration oncogene spi1 (SPI1) antibody
  • spleen focus forming virus (SFFV) proviral integration oncogene spi1b (spi1b) antibody
  • 2B1 antibody
  • Ab1-021 antibody
  • cb1086 antibody
  • CPi-23 antibody
  • Dis-1 antibody
  • Dis1 antibody
  • Gm5657 antibody
  • OF antibody
  • pu.1 antibody
  • pu1 antibody
  • Serpina3d antibody
  • Serpina3l antibody
  • Sfpi-1 antibody
  • sfpi1 antibody
  • si:by184l24.2 antibody
  • Spi-1 antibody
  • SPI-A antibody
  • SPI1 antibody
  • Spin1 antibody
  • Spin2a antibody
  • Tcfpu1 antibody
  • Tfpu.1 antibody

Protein level used designations for SPI1

SPI-1 , SPI-2.1 , contrapsin-like protease inhibitor 3 , contrapsin-like protease inhibitor-related protein , liver regeneration protein lrryan , serine protease inhibitor 1 , serine protease inhibitor 2.1 , serine protease inhibitor 2a , serine protease inhibitor A3L , serpin A3L , 31 kDa transforming protein , 31 kDa-transforming protein , SPI-1 proto-oncogene , hematopoietic transcription factor PU.1 , spleen focus forming virus (SFFV) proviral integration oncogene spi1 , transcription factor PU.1 , SFFV proviral integration 1 protein , SFFV proviral integration 1 , spleen focus forming virus proviral integration oncogene spi1 , Spi-1/PU.1 transcription factor , transcription factor spi1

GENE ID SPECIES
435318 Mus musculus
299282 Rattus norvegicus
6688 Homo sapiens
20375 Mus musculus
366126 Rattus norvegicus
395879 Gallus gallus
611255 Canis lupus familiaris
414912 Sus scrofa
507100 Bos taurus
30117 Danio rerio
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