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anti-StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4) Antibodies

Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1\; MIM 184756) and by liver X receptors (e.g., LXRA\; MIM 602423). Additionally we are shipping STARD4 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
STARD4 134429 Q96DR4
Anti-Mouse STARD4 STARD4 170459 Q99JV5
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Top anti-STARD4 Antibodies at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin fixed and paraffin embedded human kidney tissue stained with STARD4 Antibody (N-term) Cat.-No AP54067PU-Nf ollowed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STARD4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis in human placenta tissue lysates (35ug/lane) using STARD4 Antibody (N-term) Cat.-No AP54067PU-N. This demonstrates the STARD4 antibody detected the STARD4 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-STARD4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:2500Positive Control: HepG2 cell lysate WB Suggested Anti-STARD4  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.500  Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB STARD4 Antibody (N-term)  western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the STARD4 antibody detected the STARD4 protein (arrow). STARD4 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STARD4 Antibody (N-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated WB Western Blot analysis of STARD4 expression in transfected 293T cell line by STARD4 MaxPab polyclonal antibody.Lane 1: STARD4 transfected lysate(22.55 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated WB Western Blot showing STARD4 antibody used at a concentration of 1-2 ug/ml to detect its target protein. 50 μg Log in to see 7 to 9 Days
$473.93
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details

STARD4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Top referenced anti-STARD4 Antibodies

  1. Human Polyclonal STARD4 Primary Antibody for EIA, IHC (p) - ABIN954972 : Korytowski, Rodriguez-Agudo, Pilat, Girotti: StarD4-mediated translocation of 7-hydroperoxycholesterol to isolated mitochondria: deleterious effects and implications for steroidogenesis under oxidative stress conditions. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 3 references for ABIN954972

More Antibodies against STARD4 Interaction Partners

Human StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4) interaction partners

  1. Studies show the 3 steroidogenic acute regulatory-related lipid transfer (START) domain proteins StarD4, StarD5 (show STARD5 Antibodies) and StarD6 (show STARD6 Antibodies) have a similar lipid binding pocket specific for sterols (cholesterol in particular), but differing regulation and localization.

  2. The data indicate a role for STARD4 in nonvesicular transport of cholesterol from the plasma membrane and the endocytic recycling compartment to the endoplasmic reticulum and perhaps other intracellular compartments as well.

  3. cholesterol transport mediated by STARD4 is an important component of the cholesterol homeostasis regulatory machinery

  4. Study provide strong evidence for StarD4 as a highly regulated, non-vesicular, directional, intracellular transporter of cholesterol which plays a key role in the maintenance of intracellular cholesterol homeostasis.

  5. StarD4-accelerated 7 alpha-OOH transfer to mitochondria resulted in greater susceptibility to free radical lipid peroxidation and loss of membrane potential than in a non-StarD4 control.

  6. StarD4 is regulated by sterols via SREBP-2 (show SREBF2 Antibodies), and StarD5 (show STARD5 Antibodies) is activated by ER stress cholesterol metabolism; they serve different functions

  7. Induction of STARD4 depended on both transcription factor ATF6 (show ATF6 Antibodies) and an ERSE-like element in its promoter.

  8. StarD4 plays an important role as a directional cholesterol transporter in the maintenance of cellular cholesterol homeostasis

Mouse (Murine) StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4) interaction partners

  1. a model of STARD4 membrane interaction and sterol binding and release that requires dynamic movement of both the Omega1 loop and membrane insertion of the C-terminal alpha-helix.

  2. StARD4's role can largely be compensated for by other intracellular cholesterol transporters.

  3. StarD4 is regulated by sterols via SREBP-2 (show SREBF2 Antibodies), and StarD5 (show STARD5 Antibodies) is activated by ER stress cholesterol metabolism; they serve different functions

  4. StarD4 plays an important role as a directional cholesterol transporter in the maintenance of cellular cholesterol homeostasis

STARD4 Antigen Profile

Protein Summary

Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1\; MIM 184756) and by liver X receptors (e.g., LXRA\; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR\; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002

Gene names and symbols associated with STARD4

  • StAR-related lipid transfer (START) domain containing 4 (STARD4) antibody
  • StAR-related lipid transfer (START) domain containing 4 (Stard4) antibody
  • 4632419C16Rik antibody
  • 9030213J02Rik antibody
  • AA517649 antibody
  • AW324468 antibody

Protein level used designations for STARD4

START domain containing 4 sterol-regulated , START domain containing 4, sterol regulated , START domain-containing protein 4 , stAR-related lipid transfer protein 4

GENE ID SPECIES
134429 Homo sapiens
170459 Mus musculus
Selected quality suppliers for anti-STARD4 (STARD4) Antibodies
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