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anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) Antibodies

SUV39H1 is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. Additionally we are shipping Suppressor of Variegation 3-9 Homolog 1 (Drosophila) Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SUV39H1 6839 O43463
SUV39H1 20937 O54864
SUV39H1 302553  
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Top anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) Antibodies at antibodies-online.com

Showing 10 out of 88 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SUV39H1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB SUV39H1 Antibody (N-term) (ABIN657943) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the SUV39H1 antibody detected the SUV39H1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-SUV39H1 Antibody Titration: 1.25ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB SUV39H1 (ABIN387991) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the SUV39H1 antibody detected the SUV39H1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB Western analysis of extracts from 293 cells using SUV39H1 antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated ChIP, IP, WB   100 μg Log in to see 1 to 2 Days
$466.67
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

SUV39H1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) Antibodies

  1. Human Polyclonal SUV39H1 Primary Antibody for WB - ABIN387991 : Fujita, Watanabe, Ichimura, Tsuruzoe, Shinkai, Tachibana, Chiba, Nakao: Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression. in The Journal of biological chemistry 2003 (PubMed)
    Show all 6 references for ABIN387991

  2. Human Polyclonal SUV39H1 Primary Antibody for EIA, IHC (p) - ABIN356686 : Schotta, Ebert, Krauss, Fischer, Hoffmann, Rea, Jenuwein, Dorn, Reuter: Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing. in The EMBO journal 2002 (PubMed)
    Show all 5 references for ABIN356686

  3. Human Monoclonal SUV39H1 Primary Antibody for WB - ABIN387778 : Chen, Li, Zwolinska, Smith, Cross, Koomen, Yuan, Jenuwein, Marine, Wright, Chen: MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional output. in The EMBO journal 2010 (PubMed)
    Show all 5 references for ABIN387778

  4. Human Polyclonal SUV39H1 Primary Antibody for WB - ABIN657943 : Goyama, Nitta, Yoshino, Kako, Watanabe-Okochi, Shimabe, Imai, Takahashi, Kurokawa: EVI-1 interacts with histone methyltransferases SUV39H1 and G9a for transcriptional repression and bone marrow immortalization. in Leukemia 2010 (PubMed)
    Show all 5 references for ABIN657943

  5. Human Monoclonal SUV39H1 Primary Antibody for ChIP, IP - ABIN2668694 : Terada: Aurora-B/AIM-1 regulates the dynamic behavior of HP1alpha at the G2-M transition. in Molecular biology of the cell 2006 (PubMed)
    Show all 3 references for ABIN2668694

  6. Cow (Bovine) Polyclonal SUV39H1 Primary Antibody for WB - ABIN2779665 : Kang, Lee, Kim, Chang, Kyu Park, Chun, Song, Park, Kim: Association of the SUV39H1 histone methyltransferase with the DNA methyltransferase 1 at mRNA expression level in primary colorectal cancer. in International journal of cancer. Journal international du cancer 2007 (PubMed)

  7. Cow (Bovine) Polyclonal SUV39H1 Primary Antibody for IHC, WB - ABIN2779664 : Frontelo, Leader, Yoo, Potocki, Crawford, Kulik, Lechleider: Suv39h histone methyltransferases interact with Smads and cooperate in BMP-induced repression. in Oncogene 2004 (PubMed)

More Antibodies against Suppressor of Variegation 3-9 Homolog 1 (Drosophila) Interaction Partners

Human Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) interaction partners

  1. we describe the synthesis of multidomain 'designer chromatin' templates and their application to dissecting the regulation of human Suv39h1

  2. These results suggest a model in which SUV39H1 downregulation promotes the establishment of cellular senescence.

  3. CRL4B promotes tumorigenesis by coordinating with SUV39H1/HP1 (show DEFA1 Antibodies)/DNMT3A (show DNMT3A Antibodies) in DNA methylation (show HELLS Antibodies)-based epigenetic silencing

  4. PHF2 (show PHF1 Antibodies) is likely to repress rDNA transcription by competing with PHF8 (show PHF8 Antibodies) for binding of ribosomal DNA promoter and by recruiting H3K9me2/3 methyltransferase SUV39H1.

  5. High SUV39H1 expression is associated with hepatocellular carcinoma.

  6. Suv39H1 induced apoptosis and inhibited cell proliferation in the gastric cancer MGC803 cell line, while decreasing BCL-2 (show BCL2 Antibodies), pro-caspase-9 (show CASP9 Antibodies), pro-caspase-3 (show CASP3 Antibodies) and C-myc (show MYC Antibodies). Suv39H1 may be a potential gene target for anti-gastric carcinoma therapy.

  7. SUV39H1 expression was upregulated in glioma cell lines and in glioma tissues compared to normal brain, being positively correlated with grade and histological malignancy.

  8. Short-chain fatty acids from periodontal pathogens suppress EZH2 (show EZH2 Antibodies), and SUV39H1 to promote Kaposi's sarcoma-associated herpesvirus replication.

  9. Results suggest that by regulating JMJD2b (show KDM4B Antibodies) and SUV39H1 expression, p53 (show TP53 Antibodies) not only controls transcription but also promotes HC relaxation to accelerate a rate-limiting step in the repair of complex genomes.

  10. The SUV39H1 chromodomain was shown to recognize histone H3K9me2/3 specifically.

Mouse (Murine) Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) interaction partners

  1. Oct4P4 lncRNA forms a complex with the SUV39H1 HMTase to direct the imposition of H3K9me3 and HP1alpha (show CBX5 Antibodies) to the promoter of the ancestral Oct4 (show POU5F1 Antibodies) gene, located on chromosome 17, leading to gene silencing and reduced mESC self-renewal.

  2. Provide genetic evidence that Suv39h1 controls telomere homeostasis and mediates resistance to oncogenic stress in vivo, conferring resistance to skin carcinogenesis.

  3. Repeat-associated, Suv39h-dependent H3K9me3 displays a dynamic distribution that differs in the epigenome of pluripotent versus more committed cells.

  4. These findings indicate that Suv39h1 enhances AP-2alpha (show TFAP2A Antibodies)-mediated transcriptional repression of C/EBPalpha (show CEBPA Antibodies) in an epigenetic manner and further inhibits adipocyte differentiation.

  5. A-type lamins interact with SUV39H1, and prelamin A/progerin exhibits enhanced binding capacity to SUV39H1, protecting it from proteasomal degradation and, consequently, increasing H3K9me3 levels.

  6. Data indicate that loss of suv39h1 prevents Myc (show MYC Antibodies)-induced chromosomal instability.

  7. Smads recruit H3K9 methyltransferases Suv39h1 to the IL-2 (show IL2 Antibodies) promoter, thereby inducing suppressive histone methylation and inhibiting T cell receptor-mediated IL-2 (show IL2 Antibodies) transcription.

  8. SirT1 (show SIRT1 Antibodies) preserves heterochromatin structure: it modulates Suv39h1 protein levels in stress conditions by preventing MDM2 (show MDM2 Antibodies)-mediated polyubiquitination at K87.

  9. novel role for microRNA in the epigenetic regulation of inflammatory genes in vascular smooth muscle cells of diabetic mice through downregulation of SUV39h1.

  10. Ring1B (show RNF2 Antibodies) and Suv39h1 have mutually exclusive roles in regulating distinct chromatin states at key developmental genes, and play a part in how lineage specification can be reinforced during early development

Zebrafish Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) interaction partners

  1. The identification of a histone H3 (show HIST3H3 Antibodies) lysine 9 histone methyltransferase, SUV39H1, as a suppressor of embryonal rhabdomyosarcoma formation in zebrafish, is described.

  2. These results suggest that Dnmt1 (show DNMT1 Antibodies) activity helps direct histone methylation by Suv39h1 and that, together, Dnmt1 (show DNMT1 Antibodies) and Suv39h1 help guide the terminal differentiation of particular tissues.

Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) Antigen Profile

Protein Summary

This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression.

Gene names and symbols associated with SUV39H1

  • suppressor of variegation 3-9 homolog 1 (suv39h1) antibody
  • suppressor of variegation 3-9 homolog 1 (Drosophila) (SUV39H1) antibody
  • suppressor of variegation 3-9 homolog 1 (Drosophila) (Suv39h1) antibody
  • suppressor of variegation 3-9 homolog 1a (suv39h1a) antibody
  • AI852103 antibody
  • AL022883 antibody
  • DXHXS7466e antibody
  • fe02c04 antibody
  • H3-K9-HMTase 1 antibody
  • KMT1A antibody
  • MG44 antibody
  • mIS6 antibody
  • RGD1565028 antibody
  • SUV39H antibody
  • suv39h1 antibody
  • wu:fe02c04 antibody
  • zgc:101027 antibody

Protein level used designations for SUV39H1

histone-lysine N-methyltransferase SUV39H1 , su(var)3-9 homolog 1 , Su(var)3-9 homolog 1 , histone H3-K9 methyltransferase 1 , histone-lysine N-methyltransferase, H3 lysine-9 specific 1 , lysine N-methyltransferase 1A , position-effect variegation 3-9 homolog , H3-K9-HMTase 1 , Suv39h histone methyltransferase , histone-lysine N-methyltransferase SUV39H1-A , su(var)3-9 homolog 1-A , suppressor of variegation 3-9 homolog 1 , suppressor of variegation 3-9 homolog 1-A , suppressor of variegation 3-9-like 1a

GENE ID SPECIES
431943 Xenopus laevis
6839 Homo sapiens
491868 Canis lupus familiaris
523047 Bos taurus
20937 Mus musculus
302553 Rattus norvegicus
100172621 Pongo abelii
445198 Danio rerio
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