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Surfactant Protein D Proteins (SFTPD)

Contributes to the lung's defense against inhaled microorganisms. Additionally we are shipping Surfactant Protein D Antibodies (107) and Surfactant Protein D Kits (50) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SFTPD 20390 P50404
SFTPD 6441 P35247
SFTPD 25350 P35248
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Top Surfactant Protein D Proteins at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Cynomolgus His tag 50 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 2 to 3 Days
$336.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,948.00
Details
Yeast Macaca mulatta His tag   1 mg Log in to see 56 to 66 Days
$2,964.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,968.17
Details

SFTPD Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Human , , , ,
,
Rat (Rattus)

Top referenced Surfactant Protein D Proteins

  1. Cynomolgus SFTPD Protein expressed in Human Cells - ABIN2009674 : Gibbs, Pennica: CRF2-4: isolation of cDNA clones encoding the human and mouse proteins. in Gene 1997 (PubMed)
    Show all 4 references for ABIN2009674

  2. Mouse (Murine) SFTPD Protein expressed in Human Cells - ABIN2007507 : Liu, Wei, Ho, de Waal Malefyt, Moore: Expression cloning and characterization of a human IL-10 receptor. in Journal of immunology (Baltimore, Md. : 1950) 1994 (PubMed)
    Show all 4 references for ABIN2007507

  3. Human SFTPD Protein expressed in Human Cells - ABIN2003761 : Kotenko, Izotova, Mirochnitchenko, Esterova, Dickensheets, Donnelly, Pestka et al.: Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rbeta ) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, ... in The Journal of biological chemistry 2001 (PubMed)
    Show all 4 references for ABIN2003761

More Proteins for Surfactant Protein D (SFTPD) Interaction Partners

Pig (Porcine) Surfactant Protein D (SFTPD) interaction partners

  1. The authors demonstrated that the number and position of glycosylation sites determine viral susceptibility to the neutralizing activity of porcine SP-D.

  2. Data show that interactions of surfactant protein D (pSP-D) with influenza A virus mediated by the N-linked carbohydrate moiety in pSP-D depend on the terminal sialic acids present on this moiety.

  3. The presence of SP-D in endothelial cells which is NO-, PI(3 (show PI3 Proteins))K/Akt (show AKT1 Proteins)- and Erk (show MAPK1 Proteins)-dependent is demonstrated. It suggests a protective role of SP-D in these cells.

  4. The importance of SP-D in innate immunity is underlined by its expression at the potential ports of entry of pathogens: lung, tongue, intestinal tract, thymus, skin, gall bladder, lacrimal gland, esophagus, stomach, kidney, liver, prostate and spleen.

Mouse (Murine) Surfactant Protein D (SFTPD) interaction partners

  1. these results demonstrate SP-D plays protective roles by inhibiting apoptosis and modulating NF-kappaB-mediated inflammation in CLP-induced acute pancreatic injury .

  2. SP-A (show SFTPA1 Proteins)/D double knock-out mice showed increased susceptibility to urinary tract infection

  3. Human and murine data together indicate that SP-A, SP-D and MBL are synthesized in early gestational tissues, and may contribute to regulation of immune response at the feto-maternal interface during pregnancy.

  4. The presence of SP-A (show SFTPA1 Proteins) and SP-D in the murine decidua is likely to play a protective role against intrauterine infection during pregnancy.

  5. our results demonstrate that SFTPD deficiency affects female fertility, highlighting roles for SFTPD in ovarian and uterine physiology

  6. the collectin (show MBL2 Proteins) Surfactant Protein D is an essential component of host innate immunity to helminths

  7. SP-D protects the ocular surface from S. aureus infection.

  8. Estrogen positively regulates expression of SP-D in the mouse uterus. Progesterone, along with estrogen synergizes SP-D expression, however, when administered alone results in negative regulation.

  9. NOS2 (show NOS2 Proteins) mediates remodeling of septal walls, resulting in deposition of interstitial tissue in Sftpd(-/-).

  10. Suggest a protective role for SP-D in the pathogenesis of sub-epithelial fibrosis in a mouse model of allergic inflammation through regulation of eosinophil-derived TGF-beta1 (show TGFB1 Proteins).

Human Surfactant Protein D (SFTPD) interaction partners

  1. Human and murine data together indicate that SP-A, SP-D and MBL are synthesized in early gestational tissues, and may contribute to regulation of immune response at the feto-maternal interface during pregnancy.

  2. Serum SP-D may serve as a convenient medium to distinguish lung infection caused by M. pneumoniae.

  3. findings shed new light on the discovery and/or development of a useful biomarker based on glycosylation changes for diagnosing COPD (show ARCN1 Proteins).

  4. Quantitative real-time PCR experiments disclosed significantly increased leukocyte NOS2 (show NANOS2 Proteins) and SFTPD mRNA levels in hyperglycemic gestational diabetes mellitus patients (P < 0.05).

  5. Serum SP-D was not significantly different between patients with connective tissue disease-interstitial lung disease, chronic fibrosing interstitial pneumonia patients and healthy controls.

  6. Letter: report higher serum SP-D levels in bird-related hypersensitivity pneumonitis during winter.

  7. The SP-D level showed positive correlations with carotid IMT and coronary artery calcification in patients on long-term hemodialysis.

  8. SP-D is expressed differently in airways of asthmatics relative to that of non-asthmatics.

  9. Sputum and bronchoalveolar lavage fluid SFTPD were significantly higher in patients with severe asthma compared to mild-moderate asthma and healthy controls.

  10. We demonstrated for the first time in a Chinese population cohort that genetic polymorphisms of SP-D are not only associated with risk of COPD (show ARCN1 Proteins) development, but also related to disease manifestation and that they predict outcomes.

Cow (Bovine) Surfactant Protein D (SFTPD) interaction partners

  1. Elevation of SP-D is found in bronchoalveolar lavage fluid from inoculated lobes of calves infected with bovine adenovirus type 3.

  2. The bSP (show KLK6 Proteins)-D gene has 9 exons spanning about 10.5 kb on chromosome 28 at position q1.8. The 5'-upstream sequence has cis (show CISH Proteins)-regulatory elements. It has 2 (show HAS2 Proteins) polymorphisms in the carbohydrate recognition domain (242 Glu (show DCTN1 Proteins)/Val & 268 Ala/Gly).

Surfactant Protein D (SFTPD) Protein Profile

Protein Summary

Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.

Gene names and symbols associated with Surfactant Protein D Proteins (SFTPD)

  • surfactant protein D (SP-D)
  • pulmonary surfactant-associated protein D-like (LOC100728956)
  • surfactant associated protein D (Sftpd)
  • surfactant protein D (SFTPD)
  • surfactant protein D (Sftpd)
  • AI573415 protein
  • COLEC7 protein
  • PSP-D protein
  • SFTP4 protein
  • SP-D protein
  • SPD protein

Protein level used designations for Surfactant Protein D Proteins (SFTPD)

surfactant protein D , carbohydrate recognition domain , PSP-D , lung surfactant protein D , pulmonary surfactant-associated protein D , collectin 7 , collectin-7 , pulmonary surfactant apoprotein , surfactant, pulmonary-associated protein D , surfactant-associated protein, pulmonary 4 , CP4 , pulmonary surfactant protein D , surfactant associated protein D , SP-D

GENE ID SPECIES
396782 Sus scrofa
443191 Ovis aries
100728956 Cavia porcellus
20390 Mus musculus
6441 Homo sapiens
25350 Rattus norvegicus
397198 Sus scrofa
489066 Canis lupus familiaris
282072 Bos taurus
678657 Macaca mulatta
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