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anti-Synaptojanin 1 (SYNJ1) Antibodies

SYNJ1 encodes a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. Additionally we are shipping Synaptojanin 1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SYNJ1 85238 Q62910
SYNJ1 8867 O43426
SYNJ1 104015  
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Top anti-Synaptojanin 1 Antibodies at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-SYNJ1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Rat Mouse Un-conjugated IHC (fro), WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Mouse Mouse Un-conjugated WB Western blot analysis of Synaptojanin 1 on a rat cerebrum lysate. Lane 1: 1:500, lane 2: 1:1000, lane 3: 1:2000 dilution of the mouse anti-Synaptojanin 1 antibody. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Rat Mouse Un-conjugated IP, WB 0.1 mg Log in to see 6 to 8 Days
$368.50
Details
Mouse Mouse Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$368.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Rat Rabbit Un-conjugated ICC, WB dilution: 1 : 200, sample: crude synaptosomal fraction of rat brain (P2) 50 μg Log in to see 5 to 6 Days
$398.48
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

SYNJ1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Synaptojanin 1 Antibodies

  1. Rat (Rattus) Polyclonal SYNJ1 Primary Antibody for ICC, WB - ABIN1742316 : Park, Kim, Lee, Park, Park, Sun, Kim, Chang: SNX18 shares a redundant role with SNX9 and modulates endocytic trafficking at the plasma membrane. in Journal of cell science 2010 (PubMed)
    Show all 4 references for ABIN1742316

  2. Mouse (Murine) Monoclonal SYNJ1 Primary Antibody for WB - ABIN968786 : Cestra, Castagnoli, Dente, Minenkova, Petrelli, Migone, Hoffmüller, Schneider-Mergener, Cesareni: The SH3 domains of endophilin and amphiphysin bind to the proline-rich region of synaptojanin 1 at distinct sites that display an unconventional binding specificity. in The Journal of biological chemistry 1999 (PubMed)
    Show all 3 references for ABIN968786

  3. Rat (Rattus) Monoclonal SYNJ1 Primary Antibody for IHC (fro), WB - ABIN782444 : Ramjaun, McPherson: Tissue-specific alternative splicing generates two synaptojanin isoforms with differential membrane binding properties. in The Journal of biological chemistry 1996 (PubMed)
    Show all 2 references for ABIN782444

  4. Chicken Polyclonal SYNJ1 Primary Antibody for WB - ABIN2778875 : Thole, Vermeer, Zhang, Gadella, Nielsen: Root hair defective4 encodes a phosphatidylinositol-4-phosphate phosphatase required for proper root hair development in Arabidopsis thaliana. in The Plant cell 2008 (PubMed)

More Antibodies against Synaptojanin 1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Synaptojanin 1 (SYNJ1) interaction partners

  1. Mnb (show DYRK1A Antibodies) is a synaptic kinase that promotes efficient synaptic vesicle recycling by Synj function at the neuromuscular junction.

  2. Findings imply that restoring the level of any one of these genes dap160/itsn1 (show ITSN1 Antibodies), synj/synj1, and nla/dscr1 (show RCAN1 Antibodies) may reduce endocytic defects seen in DS.

  3. In the absence of synaptojanin or endophilin, vesicles undergo full fusion and re-formation.

Zebrafish Synaptojanin 1 (SYNJ1) interaction partners

  1. Synaptojanin 1 is required for endolysosomal trafficking of synaptic proteins in cone photoreceptor inner segments.

  2. This protein localized predominantly to cone photoreceptors. Using blastula stage transplantation experiments, study demonstrates that rods from mutants lacking SynJ1 develop normally and do not have the pronounced morphological defects detected in cones

  3. Synj1 is required for anchoring of ribbons, for vesicle maintenance, and for synaptic transmission at cone photoreceptor ribbon synapses.

  4. Synj1 is critical for retrieval of membrane in order to maintain the quantity, timing of fusion, and spontaneous release properties of synaptic vesicles at hair-cell ribbon synapses.

Human Synaptojanin 1 (SYNJ1) interaction partners

  1. Mutations in SYNJ1 gene do not play a major role in early-onset or familial PD in our population.

  2. This study demonstrated that SYNJ1 was significantly higher in Down syndrome and correlated with several measures of Abeta (show APP Antibodies). SYNJ1 was higher in down syndrome with Alzheimer disease and significantly higher than SYNJ1 in sporadic Alzheimer disease.

  3. This is the third reported family with autosomal recessive, early-onset parkinsonism associated with the SYNJ1 p.Arg258Gln mutation. This work contributes to the definition of the genetic and clinical aspects of PARK20.

  4. the clinical progression of the Italian siblings with SYNJ1-related early-onset atypical parkinsonism seems to present a more severe progression in the early stages

  5. Our data suggest that the previously reported Arg258Gln mutation in SYNJ1 is not a frequent cause of Parkinson disease

  6. This review presented that SYNJ1 in recessive forms of juvenile parkinsonism.

  7. Findings suggest that SYNJ1 mutation is responsible for the early-onset Parkinsonism phenotype probably due to deficiencies in its phosphatase activity and consequent impairment of its synaptic functions.

  8. Results indicate that SYNJ1 gene is a compelling candidate for Parkinsonism; mutations in the functionally linked protein auxilin (show DNAJC6 Antibodies) cause a similar early-onset phenotype, and other findings implicate endosomal dysfunctions in the pathogenesis.

  9. a novel mechanism by which reduction of a PI(4,5)P2-degrading enzyme, synj1, improves amyloid-induced neuropathology and behavior deficits through accelerating cellular Abeta (show APP Antibodies) clearance.

  10. Trisomy for SYNJ1 in Down syndrome is functionally linked to the enlargement of early endosomes.

Cow (Bovine) Synaptojanin 1 (SYNJ1) interaction partners

Mouse (Murine) Synaptojanin 1 (SYNJ1) interaction partners

  1. a novel mechanism by which reduction of a PI(4,5)P2-degrading enzyme, synj1, improves amyloid-induced neuropathology and behavior deficits through accelerating cellular Abeta (show APP Antibodies) clearance.

  2. These results implicate Pak5 (show PAK7 Antibodies) in Pacsin1 (show PACSIN1 Antibodies)- and Synaptojanin1-mediated synaptic vesicle trafficking.

  3. PI(4,5)P-to-PI4P conversion achieved by Synj1 at sites of high curvature may cooperate with dynamin (show DNM1 Antibodies) to achieve membrane fission.

  4. synaptojanin 1 function is needed for the progression of recycling vesicles to the functional synaptic vesicle pool.

  5. PtdIns(4,5)P(2) dyshomeostasis caused by gene dosage imbalance for Synj1 may contribute to brain dysfunction and cognitive disabilities in down syndrome.

  6. Synaptojanin 1 functions in constitutive and triggered internalization of AMPA (show GRIA3 Antibodies) receptors.

  7. Synaptojanin-1 is involved phosphatidylinositol metabolism in astrogliogenesis, but not in neurogenesis.

Synaptojanin 1 (SYNJ1) Antigen Profile

Protein Summary

This gene encodes a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Synaptojanin 1 (SYNJ1) Antibodies

  • synaptojanin (synj) antibody
  • synaptojanin 1 (synj1) antibody
  • synaptojanin 1 (SYNJ1) antibody
  • synaptojanin 1 (LOC100228100) antibody
  • synaptojanin 1 (Synj1) antibody
  • A930006D20Rik antibody
  • AA675315 antibody
  • CG6562 antibody
  • Dmel\\CG6562 antibody
  • fb02f11 antibody
  • fi15a11 antibody
  • INPP5G antibody
  • IPP antibody
  • mKIAA0910 antibody
  • nrc antibody
  • Synj antibody
  • SYNJ1 antibody
  • wu:fb02f11 antibody
  • wu:fi15a11 antibody

Protein level used designations for anti-Synaptojanin 1 (SYNJ1) Antibodies

CG6562-PA , CG6562-PB , CG6562-PC , synj-PA , synj-PB , synj-PC , no optokinetic response c , synaptojanin-1 , synaptojanin 1 , synaptojanin 1, isoform 1 , synaptojanin-1-like , synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1 , synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1 , inositol 5'-phosphatase (synaptojanin 1) , synaptojanin-1, polyphosphoinositide phosphatase , p150

GENE ID SPECIES
37517 Drosophila melanogaster
337236 Danio rerio
473959 Pan troglodytes
100052605 Equus caballus
100137543 Papio anubis
100228100 Taeniopygia guttata
100395303 Callithrix jacchus
100487517 Xenopus (Silurana) tropicalis
100567389 Anolis carolinensis
85238 Rattus norvegicus
418498 Gallus gallus
8867 Homo sapiens
478403 Canis lupus familiaris
282087 Bos taurus
100328807 Oryctolagus cuniculus
104015 Mus musculus
100525664 Sus scrofa
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