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plays a role in clathrin-dependent assembly of synaptic vesicles at the presynaptic terminal. Additionally we are shipping and SNAP91 Kits (2) and many more products for this protein.
Showing 10 out of 32 products:
Human Monoclonal SNAP91 Primary Antibody for IF, IP - ABIN967993
Drake, Traub: Interaction of two structurally distinct sequence types with the clathrin terminal domain beta-propeller. in The Journal of biological chemistry 2001
Show all 5 references for ABIN967993
Human Polyclonal SNAP91 Primary Antibody for ICC, IHC - ABIN1742332
Geis, Weishaupt, Hallermann, Grünewald, Wessig, Wultsch, Reif, Byts, Beck, Jablonka, Boettger, Üçeyler, Fouquet, Gerlach, Meinck, Sirén, Sigrist, Toyka, Heckmann, Sommer: Stiff person syndrome-associated autoantibodies to amphiphysin mediate reduced GABAergic inhibition. in Brain : a journal of neurology 2010
Show all 2 references for ABIN1742332
Confinement within the presynaptic bouton is mediated in part by synaptic vesicle protein association with the clathrin-based endocytic machinery to limit diffusional spread of newly exocytosed SV proteins.
The clathrin assembly role of AP180 is mediated by a long disordered C-terminal assembly domain.
To sustain efficient neurotransmission and synaptic vesicle formation, AP180 and VAMP2 (show VAMP2 Antibodies) are required.
AP180 and CALM are endocytic adaptors dedicated to the sorting of small soluble N-ethylmaleimide-sensitive-factor (show NSF Antibodies) attachment protein receptors. (Review)
unique mechanism of SNARE (show NAPA Antibodies) motif-dependent endocytic sorting and identify the ANTH domain proteins AP180 and CALM as cargo-specific adaptors for synaptobrevin (show VAMP Antibodies) endocytosis
AP180 is significantly decreased in the hippocampus of Alzheimer's disease patients and in hippocampal neurons of transgenic mice.
RNA interference-mediated knockdown of AP180 reduces the generation of Abeta1-40 and Abeta1-42, whereas CALM knockdown has no effect on Abeta (show APP Antibodies) generation.
AP180 had an overall expression similar to synaptophysin (show SYP Antibodies), the immunoreactivity for the two proteins did not always co-localize.
plays a role in clathrin-dependent assembly of synaptic vesicles at the presynaptic terminal
synaptosomal-associated protein, 91kDa homolog
, 91 kDa synaptosomal-associated protein
, clathrin coat assembly protein AP180
, clathrin coat-associated protein AP180
, phosphoprotein F1-20
, synaptosomal-associated protein, 91 kDa
, assembly protein 180 (AP180)
, synaptosomal-associated protein 91 kDa
, assembly protein, 180kDa