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Synovial Sarcoma, X Breakpoint 2 Proteins (SSX2)

The product of SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. Additionally we are shipping Synovial Sarcoma, X Breakpoint 2 Antibodies (59) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SSX2 6757 Q16385
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Top Synovial Sarcoma, X Breakpoint 2 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SSX2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

Top referenced Synovial Sarcoma, X Breakpoint 2 Proteins

  1. Human SSX2 Protein expressed in Wheat germ - ABIN1321452 : Smith, Cronk, Lang, McNeel: Expression and immunotherapeutic targeting of the SSX family of cancer-testis antigens in prostate cancer. in Cancer research 2011 (PubMed)

More Proteins for Synovial Sarcoma, X Breakpoint 2 (SSX2) Interaction Partners

Human Synovial Sarcoma, X Breakpoint 2 (SSX2) interaction partners

  1. results reveal two important phenotypes of ectopic SSX2 expression that may drive/support tumorigenesis: First, immediate induction of genomic instability, and second, long-term support of tumor cell growth.

  2. The tumor-specific pattern of expression of SSX2.

  3. primary autoantibodies against intracellular MM-specific tumor antigens SSX-2 and NY-ESO-1 (show CTAG1B Proteins) are rare but functional in multiple myeloma patients after allogeneic stem cell transplantation

  4. SS18 (show SS18 Proteins)-SSX-induced Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling appears to be of crucial biological importance in synovial sarcoma tumorigenesis and progression.

  5. SSX2, SSX3, and SSX4 are expressed in the lung tissue of only 3.5% early-stage non-small cell lung cancer patients.

  6. These results suggest that the characteristic speckle localization pattern of SS18 (show SS18 Proteins)-SSX is strongly involved in the tumorigenesis through the SSX moiety of the SS18 (show SS18 Proteins)-SSX fusion protein.

  7. the initial events that likely occur when SYT (show SS18 Proteins)-SSX2 is first expressed, and its dominant function in subverting the nuclear program of the stem cell, leading to its aberrant differentiation, as a first step toward transformation

  8. The regulation of estrogen receptor alpha (show ESR1 Proteins) signaling by target proteins of SSX2 may explain the metastatic potential of breast cancer cells.

  9. The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase (show RAB40C Proteins) interactor, RABIN3, and a novel nuclear protein (show RDBP Proteins), SSX2IP (show SSX2IP Proteins).

  10. existence of fusion with SYT (show SS18 Proteins) in synovial sarcoma

Synovial Sarcoma, X Breakpoint 2 (SSX2) Protein Profile

Protein Summary

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X\\\\;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene names and symbols associated with SSX2

  • synovial sarcoma, X breakpoint 2 (SSX2)
  • synovial sarcoma, X breakpoint 2B (SSX2B)
  • CT5.2 protein
  • CT5.2A protein
  • CT5.2b protein
  • HD21 protein
  • HOM-MEL-40 protein
  • SSX protein
  • SSX2 protein
  • SSX3 protein

Protein level used designations for SSX2

cancer/testis antigen 5.2 , cancer/testis antigen family 5, member 2a , protein SSX2 , sarcoma, synovial, X-chromosome-related 2 , synovial sarcoma, X breakpoint 2B , tumor antigen HOM-MEL-40 , cancer/testis antigen family 5, member 2b , synovial sarcoma, X breakpoint 2 , synovial sarcoma, X breakpoint 3

GENE ID SPECIES
6757 Homo sapiens
727837 Homo sapiens
741661 Pan troglodytes
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