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anti-Synovial Sarcoma Translocation, Chromosome 18 (SS18) Antibodies

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Additionally we are shipping Synovial Sarcoma Translocation, Chromosome 18 Proteins (5) and Synovial Sarcoma Translocation, Chromosome 18 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SS18 6857 P21579
SS18 268996 Q62280
SS18 361295  
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Top anti-Synovial Sarcoma Translocation, Chromosome 18 Antibodies at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HepG2/Jurkat/COLO205 cells, using SSXT Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-Fixed, Paraffin-Embedded Human Prostate stained with SS18 Western blot analysis of extracts from HepG2/Jurkat/COLO205 cells, using SS18 Antibody .The lane on the right is treated with the synthesized peptide. 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$253.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Anti-SS18 / SYT antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1104471 dilution 5 ug/ml. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human, Lung endothelium: Formalin-Fixed Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Cow Rabbit Un-conjugated IP, IHC, WB Immunohistochemical analysis of SYT staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of SYT expression in HeLa (A), Jurkat (B), A431 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged SS18 is approximately 0.3ng/ml as a capture antibody. Western Blot analysis of SS18 expression in transfected 293T cell line by SS18 monoclonal antibody (M07), clone 1C8.Lane 1: SS18 transfected lysate (Predicted MW: 45.9 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated IHC   100 μL Log in to see 8 to 10 Days
$375.83
Details

SS18 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,
,
,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-Synovial Sarcoma Translocation, Chromosome 18 Antibodies

  1. Human Polyclonal SS18 Primary Antibody for EIA, IHC (p) - ABIN1449447 : Clark, Rocques, Crew, Gill, Shipley, Chan, Gusterson, Cooper: Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma. in Nature genetics 1994 (PubMed)
    Show all 3 references for ABIN1449447

  2. Human Polyclonal SS18 Primary Antibody for WB - ABIN871660 : de Bruijn, dos Santos, Thijssen, Balemans, Debernardi, Linder, Young, Geurts van Kessel: The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10. in Oncogene 2001 (PubMed)
    Show all 2 references for ABIN871660

  3. Human Polyclonal SS18 Primary Antibody for ELISA, WB - ABIN1533910 : Brodin, Haslam, Yang, Bartolazzi, Xie, Starborg, Lundeberg, Larsson et al.: Cloning and characterization of spliced fusion transcript variants of synovial sarcoma: SYT/SSX4, SYT/SSX4v, and SYT/SSX2v. Possible regulatory role of the fusion gene product in wild type SYT ... in Gene 2001 (PubMed)

More Antibodies against Synovial Sarcoma Translocation, Chromosome 18 Interaction Partners

Human Synovial Sarcoma Translocation, Chromosome 18 (SS18) interaction partners

  1. These findings identify Syt1 (show SYT1 Antibodies) as a novel Ca(2 (show CA2 Antibodies)+)-sensitive PS1 (show PSEN1 Antibodies) modulator that could regulate synaptic ABETA (show APP Antibodies), opening avenues for novel and selective synapse targeting therapeutic strategies.

  2. One-Step reverse transcriptase real time PCR for the detection SYT-SSX (show SSX2 Antibodies) transcript is feasible as an aid in confirming the diagnosis of synovial sarcoma.

  3. membrane tethering by E-Syt1 (show ESYT1 Antibodies) (ER to PM) and by synaptotagmin (secretory vesicles to PM) undergo a similar regulation by plasma membrane lipids and cytosolic Ca(2 (show CA2 Antibodies)+).

  4. a rare variant of the SS18-SSX1 (show SSX1 Antibodies) fusion transcript, which could not be identified by routine procedures for genetic diagnosis, was detected. In addition, 8 missense mutations of cancer-related genes were confirmed

  5. A dominant negative de novo SYT1 (show SYT1 Antibodies) missense variant(I368T)altered the kinetics of synaptic vesicle endocytosis and caused an early onset dyskinetic movement disorder, severe motor delay, and profound cognitive impairment.

  6. Data suggest that calcium-dependent phosphatidylinositol 4,5-diphosphate- (PI(4,5)P2-) binding proteins (such as SYT1 (show SYT1 Antibodies), PRKCA (show PKCa Antibodies) [protein kinase C alpha (show PKCa Antibodies)], and ANXA2 (show ANXA2 Antibodies) [annexin A2 (show ANXA2 Antibodies)]) interactions with membrane microdomains are tightly regulated. [REVIEW]

  7. Case Report: bronchial biphasic synovial sarcoma with SS18 gene rearrangement.

  8. SS18-SSX (show SSX2 Antibodies)-induced Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling appears to be of crucial biological importance in synovial sarcoma tumorigenesis and progression.

  9. Whole genome analyses of a well-differentiated liposarcoma reveals novel SYT1 (show SYT1 Antibodies) and DDR2 (show DDR2 Antibodies) rearrangements.

  10. SYT gene split is associated with Synovial sarcoma.

Mouse (Murine) Synovial Sarcoma Translocation, Chromosome 18 (SS18) interaction partners

  1. disruption of the Ss18 gene results in a recessive embryonic lethal phenotype, due to placental failure caused by impairment of placental vascularization and/or chorio-allantoic fusion

  2. Syt may contribute to the signaling pathway important for various cellular functions in vivo and in vitro, and we propose that Syt-deficient MEFs would be a powerful means to understand the biological roles of SYT in vitro.

Synovial Sarcoma Translocation, Chromosome 18 (SS18) Antigen Profile

Protein Summary

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001

Gene names and symbols associated with SS18

  • synaptotagmin I (SYT1) antibody
  • synovial sarcoma translocation, chromosome 18 (SS18) antibody
  • synovial sarcoma translocation, Chromosome 18 (Ss18) antibody
  • D130059H17 antibody
  • P65 antibody
  • Ssxt antibody
  • SVP65 antibody
  • Syt antibody

Protein level used designations for SS18

synaptotagmin 1 , synaptotagmin-1 , sytI , protein SSXT , synovial sarcoma translocated to X chromosome protein , synovial sarcoma, translocated to X chromosome , synovial sarcoma associated SS18-beta , synovial sarcoma associated SS18-delta , synovial sarcoma associated SS18-gamma , synovial sarcoma-associated Ss18-alpha

GENE ID SPECIES
6857 Homo sapiens
6760 Homo sapiens
268996 Mus musculus
361295 Rattus norvegicus
100173694 Pongo abelii
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