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Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Additionally we are shipping Syntrophin, beta 2 (Dystrophin-Associated Protein A1, 59kDa, Basic Component 2) Antibodies (45) and Syntrophin, beta 2 (Dystrophin-Associated Protein A1, 59kDa, Basic Component 2) Kits (12) and many more products for this protein.
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Suggest alpha/beta2-syntrophins do not regulate ABCA1 (show ABCA1 Proteins) activity and insulin (show INS Proteins) release but may have a role in regulating glucose uptake, ERK (show EPHB2 Proteins) and SR-BI (show SCARB1 Proteins) levels, and sphingomyelin metabolism in obesity.
Results suggest DGK-zeta (show DGKZ Proteins) and syntrophins play a role at multiple stages of the fusion process.
ICA512 (show PTPRN Proteins)-CCF (show PITX1 Proteins) also dimerizes with intact ICA512 (show PTPRN Proteins) on granules, thereby displacing it from beta2-syntrophin.
conformational plasticity of the native ensemble of this PDZ domain and the regulation of insulin (show INS Proteins) secretion
patients with deficiency of beta2-syntrophin and alpha-dystrobrevin (show DTNA Proteins) presented with severe congenital weakness and died in the first year of life
Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.
59 kDa dystrophin-associated protein A1 basic component 2
, dystrophin-associated protein A1, 59kD, basic component 2