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anti-T Cell Immunoglobulin and Mucin Domain Containing 2 (TIMD2) Antibodies

Probable receptor for SEMA4A involved in the regulation of T-cell function. Additionally we are shipping TIMD2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TIMD2 171284 Q8R183
Anti-Rat TIMD2 TIMD2 287222 Q5FVR0
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Top anti-TIMD2 Antibodies at antibodies-online.com

Showing 9 out of 13 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Mouse Alexa Fluor 647 FACS, IF, IHC 25 μg Log in to see 10 to 12 Days
$135.88
Details
Mouse Mouse PE FACS 100 μg Log in to see 10 to 12 Days
$288.07
Details
Mouse Rat Un-conjugated FACS, IP, WB 0.1 mg Log in to see 3 to 4 Days
$271.76
Details
Mouse Rat Un-conjugated WB   0.1 mg Log in to see 6 to 8 Days
$555.50
Details
Mouse Rat FITC FACS   0.1 mg Log in to see 3 to 4 Days
$342.94
Details
Mouse Rat Un-conjugated Func, FACS, IP, WB   0.5 mg Log in to see 3 to 4 Days
$679.41
Details
Mouse Rat Un-conjugated FACS   500 μg Log in to see 10 to 12 Days
$364.16
Details
Mouse Rat Un-conjugated WB   100 μg Log in to see 2 to 3 Days
$319.00
Details
Mouse Rat Biotin FACS   0.1 mg Log in to see 8 to 11 Days
$333.51
Details

TIMD2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , ,
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Top referenced anti-TIMD2 Antibodies

  1. Mouse (Murine) Monoclonal TIMD2 Primary Antibody for FACS - ABIN2665415 : Chakravarti, Sabatos, Xiao, Illes, Cha, Sobel, Zheng, Strom, Kuchroo: Tim-2 regulates T helper type 2 responses and autoimmunity. in The Journal of experimental medicine 2005 (PubMed)
    Show all 3 references for ABIN2665415

  2. Mouse (Murine) Monoclonal TIMD2 Primary Antibody for FACS, IF - ABIN2658020 : Kuchroo, Umetsu, DeKruyff, Freeman: The TIM gene family: emerging roles in immunity and disease. in Nature reviews. Immunology 2003 (PubMed)
    Show all 3 references for ABIN2658020

  3. Mouse (Murine) Monoclonal TIMD2 Primary Antibody for FACS - ABIN2663929 : Kumanogoh, Marukawa, Suzuki, Takegahara, Watanabe, Chng, Ishida, Fujimura, Sakoda, Yoshida, Kikutani: Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2. in Nature 2002 (PubMed)
    Show all 3 references for ABIN2663929

  4. Mouse (Murine) Monoclonal TIMD2 Primary Antibody for Func, FACS - ABIN2476816 : Warner: Tobacco industry scientific advisors: serving society or selling cigarettes? in American journal of public health 1991 (PubMed)
    Show all 2 references for ABIN2476816

  5. Mouse (Murine) Monoclonal TIMD2 Primary Antibody for FACS - ABIN2476815 : Kawamoto, Abe, Ito, Makino, Kojima, Usui, Ma, Morimoto, Yagita, Okumura, Takasaki, Akiba: Anti-T cell immunoglobulin and mucin domain-2 monoclonal antibody exacerbates collagen-induced arthritis by stimulating B cells. in Arthritis research & therapy 2011 (PubMed)
    Show all 2 references for ABIN2476815

More Antibodies against TIMD2 Interaction Partners

Mouse (Murine) T Cell Immunoglobulin and Mucin Domain Containing 2 (TIMD2) interaction partners

  1. We concluded that pro-apoptotic effects on Th1 (show HAND1 Antibodies) population through galectin-9 (show LGALS9 Antibodies)-Tim-3 (show HAVCR2 Antibodies) pathway and the up-regulation of Tim-2 on Th2 cells might be critical to Th2-biased response of host with schistosomiasis japonica.

  2. TIM-2 signaling influences both proliferation and antibody production of B cells during the early phase of collagen-induced arthritis

  3. TIM-2 can function as an iron uptake pathway.

  4. The increased expression of the pro-inflammatory and proapoptotic genes, a higher number of apoptotic cells, and increased injury and mortality of the TIM2-deficient mice suggest a protective role of TIM2 in cisplatin-induced nephrotoxicity.

  5. TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis.

  6. expression of TIM-2 significantly impairs the induction of NFAT (show NFATC1 Antibodies) and AP-1 (show JUN Antibodies) transcriptional reporters

  7. The mTIM (show TIMELESS Antibodies)-1 structure identified a homophilic TIM-TIM adhesion interaction, whereas the mTIM (show TIMELESS Antibodies)-2 domain formed a dimer that prevented homophilic binding.

  8. There are Tim2-binding molecules on hepatocytes. Tim2-hFc inhibited differentiation & proliferation of hepatocytes in fetal liver primary culture. Down-regulation of Tim2 expression by siRNA enhanced expression of liver differentiation marker genes.

  9. Tim-2 negatively regulates the Th2 differentiation of Ag-primed T-cells and the development of EC during the effector phase.

TIMD2 Antigen Profile

Protein Summary

Probable receptor for SEMA4A involved in the regulation of T-cell function. The interaction with SEMA4A enhances T-cell activation (By similarity).

Gene names and symbols associated with TIMD2

  • T cell immunoglobulin and mucin domain containing 2 (Timd2) antibody
  • T-cell immunoglobulin and mucin domain containing 2 (Timd2) antibody
  • AA816106 antibody
  • AU019358 antibody
  • AU019662 antibody
  • C78111 antibody
  • G9D3 antibody
  • TIM-2 antibody
  • Tim2 antibody

Protein level used designations for TIMD2

T-cell immunoglobulin and mucin domain containing 2 , T-cell immunoglobulin and mucin domain-containing protein 2 , T-cell membrane protein 2 , TIMD-2 , TIM-2

GENE ID SPECIES
171284 Mus musculus
287222 Rattus norvegicus
Selected quality suppliers for anti-TIMD2 (TIMD2) Antibodies
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