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Probable receptor for SEMA4A involved in the regulation of T-cell function. Additionally we are shipping TIMD2 Proteins (3) and many more products for this protein.
Showing 9 out of 13 products:
Mouse (Murine) Monoclonal TIMD2 Primary Antibody for FACS - ABIN2665415
Chakravarti, Sabatos, Xiao, Illes, Cha, Sobel, Zheng, Strom, Kuchroo: Tim-2 regulates T helper type 2 responses and autoimmunity. in The Journal of experimental medicine 2005
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Mouse (Murine) Monoclonal TIMD2 Primary Antibody for FACS, IF - ABIN2658020
Kuchroo, Umetsu, DeKruyff, Freeman: The TIM gene family: emerging roles in immunity and disease. in Nature reviews. Immunology 2003
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Mouse (Murine) Monoclonal TIMD2 Primary Antibody for FACS - ABIN2663929
Kumanogoh, Marukawa, Suzuki, Takegahara, Watanabe, Chng, Ishida, Fujimura, Sakoda, Yoshida, Kikutani: Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2. in Nature 2002
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Mouse (Murine) Monoclonal TIMD2 Primary Antibody for Func, FACS - ABIN2476816
Warner: Tobacco industry scientific advisors: serving society or selling cigarettes? in American journal of public health 1991
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Mouse (Murine) Monoclonal TIMD2 Primary Antibody for FACS - ABIN2476815
Kawamoto, Abe, Ito, Makino, Kojima, Usui, Ma, Morimoto, Yagita, Okumura, Takasaki, Akiba: Anti-T cell immunoglobulin and mucin domain-2 monoclonal antibody exacerbates collagen-induced arthritis by stimulating B cells. in Arthritis research & therapy 2011
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We concluded that pro-apoptotic effects on Th1 (show HAND1 Antibodies) population through galectin-9 (show LGALS9 Antibodies)-Tim-3 (show HAVCR2 Antibodies) pathway and the up-regulation of Tim-2 on Th2 cells might be critical to Th2-biased response of host with schistosomiasis japonica.
TIM-2 signaling influences both proliferation and antibody production of B cells during the early phase of collagen-induced arthritis
TIM-2 can function as an iron uptake pathway.
The increased expression of the pro-inflammatory and proapoptotic genes, a higher number of apoptotic cells, and increased injury and mortality of the TIM2-deficient mice suggest a protective role of TIM2 in cisplatin-induced nephrotoxicity.
TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis.
expression of TIM-2 significantly impairs the induction of NFAT (show NFATC1 Antibodies) and AP-1 (show JUN Antibodies) transcriptional reporters
The mTIM (show TIMELESS Antibodies)-1 structure identified a homophilic TIM-TIM adhesion interaction, whereas the mTIM (show TIMELESS Antibodies)-2 domain formed a dimer that prevented homophilic binding.
There are Tim2-binding molecules on hepatocytes. Tim2-hFc inhibited differentiation & proliferation of hepatocytes in fetal liver primary culture. Down-regulation of Tim2 expression by siRNA enhanced expression of liver differentiation marker genes.
Tim-2 negatively regulates the Th2 differentiation of Ag-primed T-cells and the development of EC during the effector phase.
Probable receptor for SEMA4A involved in the regulation of T-cell function. The interaction with SEMA4A enhances T-cell activation (By similarity).
T-cell immunoglobulin and mucin domain containing 2
, T-cell immunoglobulin and mucin domain-containing protein 2
, T-cell membrane protein 2