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T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) ELISA Kits

Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Additionally we are shipping TIMD4 Antibodies (94) and TIMD4 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat TIMD4 TIMD4 497891  
Anti-Mouse TIMD4 TIMD4 276891 Q6U7R4
TIMD4 91937 Q96H15
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Top TIMD4 ELISA Kits at

Showing 1 out of 5 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 0.039 ng/ml 0.156-10 ng/mL 96 Tests Log in to see 11 to 13 Days

Top referenced TIMD4 ELISA Kits

  1. Human TIMD4 ELISA Kit for Sandwich ELISA - ABIN852560 : Chen, He, Lu, Zhou, Fang, Liu, Xu: Increased Expression of T Cell Immunoglobulin and Mucin Domain 4 Is Positively Associated with the Disease Severity of Patients with Ankylosing Spondylitis. in Inflammation 2014 (PubMed)

More ELISA Kits for TIMD4 Interaction Partners

Mouse (Murine) T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) interaction partners

  1. Blockade of Tim-4 aggravates atherosclerosis in LDL receptor (show LDLR ELISA Kits) knockout mice likely by prevention of phagocytosis of phosphatidylserine-expressing apoptotic cells and activated T cells by Tim-4-expressing cells.

  2. results indicate that Tim-4 is involved in negative regulation of NO production in macrophages, suggesting the critical role of Tim-4 in immune related diseases

  3. TIM-4 on dendritic cells plays a critical role in hepatic ischemia-reperfusion (IR) injury and may be an efficient target for the prevention of liver or other organ IR injuries.

  4. M2-like TIM-4hiCD169+ tissue-resident macrophages are immunoregulatory and promote engraftment of cardiac allografts, but their influence is diminished by TIM-4-dependent programmed cell death

  5. intrinsic macrophage-specific TIM-4 signaling has indispensable role in innate immunity-driven liver ischemia-reperfusion injury

  6. TIM4 engages integrins as coreceptors to evoke the signal transduction needed to internalize PtdSer-bearing targets such as apoptotic cells.

  7. Tim-4 expression was higher in Behcet's disease (BD) mice than that in BDN mice.

  8. In addition to the known phosphatidylserine(PS) binding pocket, Tim4 has four weaker sites of interaction, making it sensitive to PS surface concentration in a manner capable of differential recognition on the basis of PS exposure level.

  9. the engulfment of apoptotic cells by resident peritoneal macrophages proceeds in two steps: binding to Tim4, a PtdSer receptor, followed by MerTK (show MERTK ELISA Kits)-mediated cell engulfment

  10. Data suggest that trans-membrane (or T cell) immunoglobulin and mucin (show SLC13A2 ELISA Kits) (TIM) molecules are expressed in embryonic hematopoietic tissues in chicken and mouse and that in fetal liver, TIM-4 is expressed by myeloid progenitor cells.

Human T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) interaction partners

  1. TIM-4 rs7700944 and not TIM-1 rs41297579 G>A (-1454) is associated with rheumatoid arthritis(RA) in the present cohort of Egyptian and may be a risk factor for development of RA in Egyptian.

  2. Data showed up-regulation of TIM-4 in lung cancer tissues and a correlation with poor prognosis. Also, TIM-4 was found to promote growth of lung cancer cells by its interaction with integrin alphavbeta3 (show ITGAV ELISA Kits) through its RGD motif.

  3. Tim-4 expression on monocytes and Tim-4 level in plasma were more highly increased in ankylosing spondylitis patients than in controls.

  4. Our results do not support an association between the rs7700944 polymorphism of the TIM-4 gene and rheumatoid arthritis

  5. Data suggest that genetic polymorphisms in ANGPTL3 (angiopoietin-like 3 (show ANGPTL3 ELISA Kits) protein), TIMD4 (T cell immunoglobulin mucin-4 (show MUC4 ELISA Kits)), and apolipoproteins A5 and B are among the genetic determinants of hypertriglyceridemia in Amerindian populations. [REVIEW]

  6. TIM4 expression is promoted by Cockroach allergen Bla (show LACTB ELISA Kits) g 7 in dendritic cells leading to Th2 polarization

  7. TIM-1 and TIM-4 are novel targets for ADAM10 (show ADAM10 ELISA Kits)- and ADAM17 (show ADAM17 ELISA Kits)-mediated ectodomain shedding.

  8. FG-CC' siRNA blocking interaction of Tim-1 and Tim-4 can enhance dendritic cell vaccine activity against gastric cancer.

  9. There were four SNPs in the promoter region of TIM4 in asthma patients of Chinese Han population, which were in linkage disequilibrium.

  10. TIM-4 variant or a highly correlated nearby gene of the TIM-4 gene may play a critical role in the pathogenesis of rheumatoid arthritis in many ethnicities.

TIMD4 Antigen Profile

Antigen Summary

Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Involved in regulating T-cell proliferation and lymphotoxin signaling. Ligand for HAVCR1/TIMD1.

Gene names and symbols associated with TIMD4

  • T-cell immunoglobulin and mucin domain containing 4 (Timd4) antibody
  • T-cell immunoglobulin and mucin domain containing 4 (TIMD4) antibody
  • T-cell immunoglobulin and mucin domain containing 4 (timd4) antibody
  • T cell immunoglobulin and mucin domain containing 4 (Timd4) antibody
  • B430010N18Rik antibody
  • MGC99322 antibody
  • RGD1564516 antibody
  • SMUCKLER antibody
  • TIM-4 antibody
  • TIM4 antibody
  • TIMD4 antibody

Protein level used designations for TIMD4

T-cell immunoglobulin and mucin domain containing 4 , T-cell immunoglobulin and mucin domain-containing protein 4 , T-cell membrane protein 4 , TIMD-4 , smuckler , spleen, mucin-containing, knockout of lymphotoxin protein , TIM-4

497891 Rattus norvegicus
416250 Gallus gallus
447692 Xenopus laevis
462217 Pan troglodytes
489160 Canis lupus familiaris
507549 Bos taurus
100597340 Nomascus leucogenys
276891 Mus musculus
91937 Homo sapiens
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