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anti-TAR DNA Binding Protein (TARDBP) Antibodies

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Additionally we are shipping TAR DNA Binding Protein Kits (33) and TAR DNA Binding Protein Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TARDBP 23435 Q13148
TARDBP 230908 Q921F2
TARDBP 298648  
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Top anti-TAR DNA Binding Protein Antibodies at antibodies-online.com

Showing 10 out of 233 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-TARDBP Antibody  Positive Control: Lane 1:41 µg mouse brain cytoplasm Lane 2: uug mouse brain nucleus Primary Antibody Dilution: 1:u000Secondary Antibody: Anti rabbit - IR-dyeSecondry  Antibody Dilution: 1:u0,000Submitted by: Anonymous 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated IHC, WB Immunohistochemistry with Thymus tissue at an antibody concentration of 5µg/ml using anti-TARDBP antibody (ARP35837_P050) 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB TARDBP Antibody (N-term) (ABIN657685) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the TARDBP antibody detected the TARDBP protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-TARDBP Antibody Titration: 1.25ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-TARDBP Antibody Titration: 1.25ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, IF, WB Immunocytochemistry of TDP43 in HeLa cells with this product at 5 μg/ml. Western blot analysis of TDP43 in L1210 cell lysate with this product at (A) 0.5, (B) 1 and (C) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Goat Un-conjugated ELISA, WB ABIN334503 (0.3 ug/ml) staining of Jurkat lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IF, WB 50 μg Log in to see 6 to 8 Days
$308.00
Details
Human Rabbit Un-conjugated IHC (fro), WB Western blot of neonatal Rat brain lysate showing specific immunolabeling of the ~ 43 kDa TDP43 protein. 0.1 mL Log in to see 6 to 8 Days
$412.50
Details

TARDBP Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-TAR DNA Binding Protein Antibodies

  1. Human Polyclonal TARDBP Primary Antibody for EIA, IF - ABIN500883 : Buratti, Dörk, Zuccato, Pagani, Romano, Baralle: Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping. in The EMBO journal 2001 (PubMed)
    Show all 3 references for ABIN500883

  2. Human Polyclonal TARDBP Primary Antibody for IHC (fro), WB - ABIN784609 : Forman, Trojanowski, Lee: TDP-43: a novel neurodegenerative proteinopathy. in Current opinion in neurobiology 2008 (PubMed)
    Show all 3 references for ABIN784609

  3. Human Monoclonal TARDBP Primary Antibody for EIA, IHC (p) - ABIN317572 : Kabashi, Valdmanis, Dion, Spiegelman, McConkey, Vande Velde, Bouchard, Lacomblez, Pochigaeva, Salachas, Pradat, Camu, Meininger, Dupre, Rouleau: TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis. in Nature genetics 2008 (PubMed)
    Show all 2 references for ABIN317572

  4. Chicken Polyclonal TARDBP Primary Antibody for IHC, WB - ABIN2780849 : Buratti, Brindisi, Giombi, Tisminetzky, Ayala, Baralle: TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: an important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing. in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 references for ABIN2780849

  5. Chicken Polyclonal TARDBP Primary Antibody for IHC, WB - ABIN2780848 : Estes, Boehringer, Zwick, Tang, Grigsby, Zarnescu: Wild-type and A315T mutant TDP-43 exert differential neurotoxicity in a Drosophila model of ALS. in Human molecular genetics 2011 (PubMed)
    Show all 2 references for ABIN2780848

  6. Human Polyclonal TARDBP Primary Antibody for IF, WB - ABIN318898 : Ou, Wu, Harrich, García-Martínez, Gaynor: Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs. in Journal of virology 1995 (PubMed)

  7. Human Polyclonal TARDBP Primary Antibody for IF, IHC (p) - ABIN657685 : Kim, Shanware, Bowler, Tibbetts: Amyotrophic lateral sclerosis-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to co-regulate HDAC6 mRNA. in The Journal of biological chemistry 2010 (PubMed)

  8. Human Polyclonal TARDBP Primary Antibody for ELISA, WB - ABIN334503 : Zhang, Xu, Dickey, Buratti, Baralle, Bailey, Pickering-Brown, Dickson, Petrucelli: Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 (PubMed)

More Antibodies against TAR DNA Binding Protein Interaction Partners

Human TAR DNA Binding Protein (TARDBP) interaction partners

  1. TDP-43 does not critically regulate expression or splicing of tau in Alzheimer's disease suggesting that TDP-43 contributes to Alzheimer's disease through mechanisms independent of tau.

  2. Study identifies a common mechanism of transport into neurites of proteins linked to the pathology of Alzheimer's disease (i.e. sAPP) and ALS (show IGFALS Antibodies) (i.e. FUS (show FUS Antibodies), TDP-43 and SOD1 (show SOD1 Antibodies))

  3. RNA binding proteins TDP-43 and FUS (show FUS Antibodies) do not consistently fit the currently characterised inclusion models suggesting that cells have a larger repertoire for generating inclusions than currently thought.

  4. TDP-43 does have dynamic inter-domain interactions, which are coordinated by the intrinsically-disordered prion (show PRNP Antibodies)-like domain.

  5. Data indicate that the structure of TAR DNA-binding protein-43 (TDP-43)consists of an alpha-helix and six beta-strands.

  6. Knockdown of TDP-43 results in an increase in viral titers, suggesting a protective role for TDP-43 in CVB3 infection.

  7. Data suggest that TRIM16 (show TRIM16 Antibodies) and TDP43 are both good prognosis indicators; data shows that TRIM16 (show TRIM16 Antibodies) inhibits cancer cell viability by a novel mechanism involving interaction and stabilisation of TDP43 with consequent effects on E2F1 (show E2F1 Antibodies) and pRb (show RB1 Antibodies) proteins.

  8. results support a model whereby dFMRP (show FMR1 Antibodies) can modulate the neurotoxicity caused by TDP-43 overexpression

  9. TDP-43 pathology in the basal forebrain is strongly associated with hippocampal sclerosis-aging.

  10. Results suggest that functional deficits in iTDP-43(A315T) mice are at least in part a direct and transient effect of the presence of TDP-43(A315T) and illustrate the compensatory capacity of compromised neurons once transgenic TDP-43 is removed

Mouse (Murine) TAR DNA Binding Protein (TARDBP) interaction partners

  1. Data demonstrate the existence of a physiological decrease of TDP-43/TBPH levels with aging in brain tissue both in wild-type mice and flies, showing that it is an evolutionary conserved phenomenon

  2. This study demonistrated that proprioceptive nerve endings in muscles revealed early and alterations at Ia/II proprioceptive nerve endings in muscle spindles and in the absence of alterations in alpha-motor axons in TDP43(A315T) transgenic mice.

  3. UBQLN2 (show UBQLN2 Antibodies) dysregulation in neurons can drive NF-kappaB (show NFKB1 Antibodies) activation and cytosolic TDP-43 aggregation.

  4. These findings demonstrate a role for PABPN1 (show PABPN1 Antibodies) in rescuing several cytopathological features of TDP-43 proteinopathy by increasing the turnover of pathologic proteins.

  5. identifies DDX58 (show DDX58 Antibodies) and MTHFSD as two TDP-43 targets that are misregulated in amyotrophic lateral sclerosis. 1

  6. Valproate Attenuates 25-kDa C-Terminal Fragment of TDP-43-Induced Neuronal Toxicity via Suppressing Endoplasmic Reticulum Stress and Activating Autophagy.

  7. we observed a glial reaction and an activity-dependent modification of Shh (show SHH Antibodies), Noggin (show NOG Antibodies), and Numb (show NUMB Antibodies) proteins. we found that Shh (show SHH Antibodies) and Noggin (show NOG Antibodies) could affect motor performance and that these proteins could be associated with both TDP-43 and Numb (show NUMB Antibodies)

  8. The ability of TDP-43 to promote CD14 (show CD14 Antibodies)-mediated activation of microglial NF-kappaB (show NFKB1 Antibodies) and AP-1 (show JUN Antibodies) pathways, as well as the NLRP3 (show NLRP3 Antibodies) inflammasome.

  9. Depletion of TDP-43 leads to a dramatic reduction in the RNA processing and the protein levels of IL-6 (show IL6 Antibodies) in serum.

  10. our results reveal a previously unrecognized non-cell-autonomous mechanism in TDP-43-mediated neurodegeneration, identifying COX-2 (show COX2 Antibodies)-PGE2 as the molecular events of microglia- but not astrocyte-initiated neurotoxicity

Zebrafish TAR DNA Binding Protein (TARDBP) interaction partners

  1. Data indicate a method for site-directed single nucleotide editing in two disease-related genes, DNA binding protein (show CNBP Antibodies) tardbp and RNA binding protein fus (show FUS Antibodies).

  2. Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowth.

  3. TARDBP and FUS (show FUS Antibodies) act in a pathogenic pathway that is independent of SOD1 (show SOD1 Antibodies).

TAR DNA Binding Protein (TARDBP) Antigen Profile

Protein Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

Gene names and symbols associated with TARDBP

  • TAR DNA binding protein (TARDBP) antibody
  • Tardbp protein (tardbp) antibody
  • TAR DNA binding protein (tardbp) antibody
  • TAR DNA binding protein (Tardbp) antibody
  • TAR DNA-binding protein 43-like (LOC100621383) antibody
  • 1190002A23Rik antibody
  • ALS10 antibody
  • C85084 antibody
  • DKFZp459I2127 antibody
  • tardbp antibody
  • TDP-43 antibody
  • Tdp43 antibody
  • wu:fb77f02 antibody
  • wu:fc52g10 antibody

Protein level used designations for TARDBP

TAR DNA binding protein , TAR DNA-binding protein 43 , Tardbp protein , TDP-43 , TAR DNA-binding protein-43

GENE ID SPECIES
100174676 Pongo abelii
457942 Pan troglodytes
713860 Macaca mulatta
778772 Ciona intestinalis
100051482 Equus caballus
100602228 Nomascus leucogenys
380329 Xenopus laevis
419453 Gallus gallus
23435 Homo sapiens
478234 Canis lupus familiaris
540632 Bos taurus
230908 Mus musculus
298648 Rattus norvegicus
325052 Danio rerio
100718595 Cavia porcellus
101114038 Ovis aries
100621383 Sus scrofa
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