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TAR DNA Binding Protein Proteins (TARDBP)

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Additionally we are shipping TAR DNA Binding Protein Antibodies (233) and TAR DNA Binding Protein Kits (33) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TARDBP 23435 Q13148
TARDBP 230908 Q921F2
Rat TARDBP TARDBP 298648  
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Top TAR DNA Binding Protein Proteins at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 20 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$767.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$792.00
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$3,135.00
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,151.50
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 11 to 12 Days
$362.88
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Escherichia coli (E. coli) Human GST tag   50 μg Log in to see 10 to 12 Days
$570.24
Details

TARDBP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

Top referenced TAR DNA Binding Protein Proteins

  1. Human TARDBP Protein expressed in Escherichia coli (E. coli) - ABIN1098222 : Ou, Wu, Harrich, García-Martínez, Gaynor: Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs. in Journal of virology 1995 (PubMed)

More Proteins for TAR DNA Binding Protein (TARDBP) Interaction Partners

Human TAR DNA Binding Protein (TARDBP) interaction partners

  1. TDP-43 does not critically regulate expression or splicing of tau in Alzheimer's disease suggesting that TDP-43 contributes to Alzheimer's disease through mechanisms independent of tau.

  2. Study identifies a common mechanism of transport into neurites of proteins linked to the pathology of Alzheimer's disease (i.e. sAPP) and ALS (show IGFALS Proteins) (i.e. FUS (show FUS Proteins), TDP-43 and SOD1 (show SOD1 Proteins))

  3. RNA binding proteins TDP-43 and FUS (show FUS Proteins) do not consistently fit the currently characterised inclusion models suggesting that cells have a larger repertoire for generating inclusions than currently thought.

  4. TDP-43 does have dynamic inter-domain interactions, which are coordinated by the intrinsically-disordered prion (show PRNP Proteins)-like domain.

  5. Data indicate that the structure of TAR DNA-binding protein-43 (TDP-43)consists of an alpha-helix and six beta-strands.

  6. Knockdown of TDP-43 results in an increase in viral titers, suggesting a protective role for TDP-43 in CVB3 infection.

  7. Data suggest that TRIM16 (show TRIM16 Proteins) and TDP43 are both good prognosis indicators; data shows that TRIM16 (show TRIM16 Proteins) inhibits cancer cell viability by a novel mechanism involving interaction and stabilisation of TDP43 with consequent effects on E2F1 (show E2F1 Proteins) and pRb (show RB1 Proteins) proteins.

  8. results support a model whereby dFMRP (show FMR1 Proteins) can modulate the neurotoxicity caused by TDP-43 overexpression

  9. TDP-43 pathology in the basal forebrain is strongly associated with hippocampal sclerosis-aging.

  10. Results suggest that functional deficits in iTDP-43(A315T) mice are at least in part a direct and transient effect of the presence of TDP-43(A315T) and illustrate the compensatory capacity of compromised neurons once transgenic TDP-43 is removed

Mouse (Murine) TAR DNA Binding Protein (TARDBP) interaction partners

  1. Data demonstrate the existence of a physiological decrease of TDP-43/TBPH levels with aging in brain tissue both in wild-type mice and flies, showing that it is an evolutionary conserved phenomenon

  2. This study demonistrated that proprioceptive nerve endings in muscles revealed early and alterations at Ia/II proprioceptive nerve endings in muscle spindles and in the absence of alterations in alpha-motor axons in TDP43(A315T) transgenic mice.

  3. UBQLN2 (show UBQLN2 Proteins) dysregulation in neurons can drive NF-kappaB (show NFKB1 Proteins) activation and cytosolic TDP-43 aggregation.

  4. These findings demonstrate a role for PABPN1 (show PABPN1 Proteins) in rescuing several cytopathological features of TDP-43 proteinopathy by increasing the turnover of pathologic proteins.

  5. identifies DDX58 (show DDX58 Proteins) and MTHFSD as two TDP-43 targets that are misregulated in amyotrophic lateral sclerosis. 1

  6. Valproate Attenuates 25-kDa C-Terminal Fragment of TDP-43-Induced Neuronal Toxicity via Suppressing Endoplasmic Reticulum Stress and Activating Autophagy.

  7. we observed a glial reaction and an activity-dependent modification of Shh (show SHH Proteins), Noggin (show NOG Proteins), and Numb (show NUMB Proteins) proteins. we found that Shh (show SHH Proteins) and Noggin (show NOG Proteins) could affect motor performance and that these proteins could be associated with both TDP-43 and Numb (show NUMB Proteins)

  8. The ability of TDP-43 to promote CD14 (show CD14 Proteins)-mediated activation of microglial NF-kappaB (show NFKB1 Proteins) and AP-1 (show JUN Proteins) pathways, as well as the NLRP3 (show NLRP3 Proteins) inflammasome.

  9. Depletion of TDP-43 leads to a dramatic reduction in the RNA processing and the protein levels of IL-6 (show IL6 Proteins) in serum.

  10. our results reveal a previously unrecognized non-cell-autonomous mechanism in TDP-43-mediated neurodegeneration, identifying COX-2-PGE2 as the molecular events of microglia- but not astrocyte-initiated neurotoxicity

Zebrafish TAR DNA Binding Protein (TARDBP) interaction partners

  1. Data indicate a method for site-directed single nucleotide editing in two disease-related genes, DNA binding protein (show CNBP Proteins) tardbp and RNA binding protein fus (show FUS Proteins).

  2. Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowth.

  3. TARDBP and FUS (show FUS Proteins) act in a pathogenic pathway that is independent of SOD1 (show SOD1 Proteins).

TAR DNA Binding Protein (TARDBP) Protein Profile

Protein Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

Gene names and symbols associated with TARDBP

  • TAR DNA binding protein (TARDBP)
  • Tardbp protein (tardbp)
  • TAR DNA binding protein (tardbp)
  • TAR DNA binding protein (Tardbp)
  • TAR DNA-binding protein 43-like (LOC100621383)
  • 1190002A23Rik protein
  • ALS10 protein
  • C85084 protein
  • DKFZp459I2127 protein
  • tardbp protein
  • TDP-43 protein
  • Tdp43 protein
  • wu:fb77f02 protein
  • wu:fc52g10 protein

Protein level used designations for TARDBP

TAR DNA binding protein , TAR DNA-binding protein 43 , Tardbp protein , TDP-43 , TAR DNA-binding protein-43

GENE ID SPECIES
100174676 Pongo abelii
457942 Pan troglodytes
713860 Macaca mulatta
778772 Ciona intestinalis
100051482 Equus caballus
100602228 Nomascus leucogenys
380329 Xenopus laevis
419453 Gallus gallus
23435 Homo sapiens
478234 Canis lupus familiaris
540632 Bos taurus
230908 Mus musculus
298648 Rattus norvegicus
325052 Danio rerio
100718595 Cavia porcellus
101114038 Ovis aries
100621383 Sus scrofa
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