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May act as a GTPase-activating protein for Rab family protein(s) (By similarity). Additionally we are shipping TBC1D14 Antibodies (13) and many more products for this protein.
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TRAPPC8 modulates autophagy and secretory trafficking and is required for TBC1D14 to bind TRAPPIII.
TBC1D14 binds activated Rab11 (show RAB11A Proteins) but is not a GAP for Rab11 (show RAB11A Proteins), and loss of Rab11 (show RAB11A Proteins) prevents TBC1D14-induced tubulation of recycling endosomes.
crystal structures of the first two mammalian TBCs, human TBC1 (show TBC1D1 Proteins) family members 22A (TBC1D22A (show TBC1D22A Proteins)) and 14 (TBC1D14)
May act as a GTPase-activating protein for Rab family protein(s) (By similarity).
TBC1 domain family, member 14
, spermatogenesis-related factor 2
, TBC1 domain family member 14
, Up-regulated in nephrectomized rat kidney 2