anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) Antibodies

TIMP3 belongs to the TIMP gene family. Additionally we are shipping TIMP3 Kits (106) and TIMP3 Proteins (20) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TIMP3 7078 P35625
TIMP3 25358  
TIMP3 21859 P39876
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Top anti-TIMP3 Antibodies at antibodies-online.com

Showing 10 out of 190 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB TIMP3 Antibody (Center) flow cytometric analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Formalin-fixed and paraffin-embedded human breast carcinoma reacted with TIMP3 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse liver tissue labeled with Anti-TIMP-3 Polyclonal Antibody (ABIN668361), Unconjugated at 1:100, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse liver tissue labeled with Anti-TIMP-3 Polyclonal Antibody , Unconjugated at 1:100, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HuvEc cells, using TIMP3 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB The TIMP-3 Antibody is used in Western blot to detect TIMP-3 in rat liver lysates. TIMP-3 staining in human stomach cancer. Paraffin-embedded human stomach cancer is stained with TIMP-3 Antibody used at 1:200 dilution. 0.1 mg Log in to see 2 to 6 Days
$327.00
Details
Human Mouse PE FACS Detection of TIMP-3 in MDA-MB-231 Human Cell Line by Flow Cytometry. MDA-MB-231 human breast cancer cell line was stained with Mouse Anti-Human TIMP-3 PE-conjugated Monoclonal Antibody. Detection of TIMP-3 in MDA-MB-231 Human Cell Line by Flow Cytometry. MDA-MB-231 human breast cancer cell line was stained with Mouse Anti-Human TIMP-3 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$320.25
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TIMP3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: MCF7 cell lysate WB Suggested Anti-TIMP3  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-TIMP3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: MCF7 cell lysate WB Suggested Anti-TIMP3  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated ELISA, WB Anti-TIMP3 antibody, Western blotting Lane 1: Recombinant Human TIMP3 Protein 10ng Lane 2: Recombinant Human TIMP3 Protein 5ng Lane 3: Recombinant Human TIMP3 Protein 2.5ng 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC (p) 7 mL Log in to see 21 to 31 Days
$164.00
Details

TIMP3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TIMP3 Antibodies

  1. Human Polyclonal TIMP3 Primary Antibody for IF (p), IHC (p) - ABIN668361 : Liu, Cui, Ao, Zhou, Zhou, Yuan, Xiang, Liu, Cao et al.: Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of ... in Toxicology and applied pharmacology 2011 (PubMed)
    Show all 5 references for 668361

  2. Human Polyclonal TIMP3 Primary Antibody for EIA, FACS - ABIN955222 : Wick, Härönen, Mumberg, Bürger, Olsen, Budarf, Apte, Müller: Structure of the human TIMP-3 gene and its cell cycle-regulated promoter. in The Biochemical journal 1995 (PubMed)
    Show all 2 references for 955222

  3. Human Polyclonal TIMP3 Primary Antibody for IHC, ELISA - ABIN1585860 : Nakasone, Terasako-Saito, Yamazaki, Sato, Tanaka, Sakamoto, Kurita, Yamasaki, Wada, Ishihara, Kawamura, Machishima, Ashizawa, Kimura, Kikuchi, Tanihara, Kanda, Kako, Nishida, Yamada, Kanda: Impact of high-/middle-molecular-weight adiponectin on the synthesis and regulation of extracellular matrix in dermal fibroblasts. in Experimental hematology 2014 (PubMed)

  4. Human Monoclonal TIMP3 Primary Antibody for FACS - ABIN4896675 : Mahller, Vaikunth, Ripberger, Baird, Saeki, Cancelas, Crombleholme, Cripe: Tissue inhibitor of metalloproteinase-3 via oncolytic herpesvirus inhibits tumor growth and vascular progenitors. in Cancer research 2008 (PubMed)

  5. Human Polyclonal TIMP3 Primary Antibody for ELISA, WB - ABIN1533421 : Silbiger, Jacobsen, Cupples, Koski: Cloning of cDNAs encoding human TIMP-3, a novel member of the tissue inhibitor of metalloproteinase family. in Gene 1994 (PubMed)

More Antibodies against TIMP3 Interaction Partners

Human TIMP Metallopeptidase Inhibitor 3 (TIMP3) interaction partners

  1. Electrostatic potential calculations suggested a competition between negatively charged GAGs and highly negatively charged complement-like domains of LRP-1 (show LRP1 Antibodies) for the binding to a positively charged area of TIMP-3 as an underlying mechanism.

  2. TIMP3 overexpression after myocardial infarction improves myocardial structural remodeling and function by promoting angiogenesis and inhibiting early proteolysis.

  3. Single Nucleotide Variants of Candidate Genes in Aggrecan (show ACAN Antibodies) Metabolic Pathway Are Associated with Lumbar Disc Degeneration and Modic Changes

  4. Our data suggest that miR (show MLXIP Antibodies)-206 may function as an inflammatory regulator and drive the expression of MMP9 (show MMP9 Antibodies) in M.tb-infected THP-1 (show GLI2 Antibodies) cells by targeting TIMP3, indicating that miR (show MLXIP Antibodies)-206 is a potential therapeutic target for patients with TB.

  5. Plasma TIMP3 is a biomarker for predicting the tumor stage in patients with oral squamous cell carcinoma .

  6. TIMP-3 K26A/K45A retained higher affinity for sulfated (show SULF1 Antibodies) glycosaminoglycans than K42A/K110A and exhibited increased affinity for ADAMTS-5 (show ADAMTS5 Antibodies) in the presence of heparin.

  7. Of the 225 genetic tests performed, 150 were for recessive IRD (show SCRIB Antibodies), and 75 were for dominant IRD (show SCRIB Antibodies). A positive molecular diagnosis was made in 70 (59%) of probands with recessive IRD (show SCRIB Antibodies) and 19 (26%) probands with dominant IRD (show SCRIB Antibodies). Thirty-two novel variants were identified; among these, 17 sequence changes in four genes were predicted to be possibly or probably damaging including: ABCA4 (show ABCA4 Antibodies) (14), BEST1 (show BEST1 Antibodies) (2), PRPH2 (show PRPH2 Antibodies) (1), and TIMP3

  8. Study evaluated MMP-12 (show MMP12 Antibodies) and TIMP-1 (show TIMP1 Antibodies), TIMP-2 (show TIMP2 Antibodies), TIMP-3, and TIMP-4 (show TIMP4 Antibodies) levels in 40 patients with asymptomatic and symptomatic critical carotid artery stenosis (CAS (show CSE1L Antibodies)) with neurologic symptoms onset within the preceding 12 hours; results suggest that MMP-12 (show MMP12 Antibodies) is related to critical CAS (show CSE1L Antibodies) independently on symptoms, moreover, TIMP-3 and TIMP-4 (show TIMP4 Antibodies) seem to be specifically related to stroke

  9. A total of 1096 subjects from eight studies were included in the present meta-analysis. Overall, a significant association between TIMP-3 methylation and gastric cancer risk was observed (OR = 8.65; 95% CI4.31-17.37; p < 0.001). Our results show a positive correlation between TIMP-3 promoter methylation and gastric cancer risk and that TIMP-3 promoter methylation may be used as a molecular marker for gastric cancer

  10. TIMP-3 expression is suppressed by promoter methylation in HCC (show FAM126A Antibodies).

Rabbit TIMP Metallopeptidase Inhibitor 3 (TIMP3) interaction partners

  1. Circulating smoke components, including acrolein, contribute to vascular diseases through enhanced MMP-1 (show MMP1 Antibodies) and decreased TIMP-3 secretion.

  2. TIMP-3 is downregulated in a distinct subpopulation of atherosclerotic foam cells which have increased MMP-14 (show MMP14 Antibodies).

Cow (Bovine) TIMP Metallopeptidase Inhibitor 3 (TIMP3) interaction partners

  1. Reactive oxygen species mediate TGF-beta1 (show TGFB1 Antibodies)-induced TIMP-3 gene expression

  2. TIMP3 has a role in the pericyte-induced stabilization of newly formed vascular networks that are predisposed to undergo regression and reveal specific molecular targets of the inhibitors regulating these events.

  3. TIMP3 mRNA expression level was upregulated by multidirectional articular motion.

Xenopus laevis TIMP Metallopeptidase Inhibitor 3 (TIMP3) interaction partners

  1. only the N-terminal, but not the C-terminal domain of TIMP-3, results in developmental defects.

  2. metamorphic tail and intestine RNA levels of TIMP-2 (show TIMP2 Antibodies), MT1-MMP (show MMP14 Antibodies) and Gel-A, but not MT3-MMP (show MMP24 Antibodies) or TIMP-3, are elevated during periods of cell death and proliferation

Mouse (Murine) TIMP Metallopeptidase Inhibitor 3 (TIMP3) interaction partners

  1. TIMP3 promotes normal microvascular endothelial cell barrier function, at least partially, through inhibition of metalloproteinase-dependent disruption of adherens junctions, and septic downregulation of TIMP3 may contribute to septic MVEC barrier dysfunction.

  2. data strongly suggest that TIMP3 has direct neuroprotective effects that can mitigate the deleterious effects associated with TBI, an area with few if any therapeutic options.

  3. Elevated levels of TIMP3 and vitronectin (show VTN Antibodies), acting downstream of Notch3 (show NOTCH3 Antibodies)(ECD (show ECD Antibodies)) deposition, play a role in CADASIL (show NOTCH3 Antibodies), producing divergent influences on early CBF (show CEBPZ Antibodies) deficits and later white matter lesions.

  4. 4-Hydroxyisoleucine improved insulin (show INS Antibodies) resistant-like state in 3T3-L1 adipocytes by targeting TACE (show ADAM17 Antibodies)/TIMP3 and the insulin (show INS Antibodies) signaling pathway.

  5. In a mouse model of prostate cancer, increased tumor growth, proliferation index, increased microvascular density, and invasion was observed in Pten (show PTEN Antibodies)(-/-), Timp3(-/-) prostate tumors compared to Pten (show PTEN Antibodies)(-/-), Timp3(+/+) tumors.

  6. Timp3 status determines p53 (show TP53 Antibodies), p38 (show CRK Antibodies) and Notch (show NOTCH1 Antibodies) coactivation to instruct hepatic cell fate and transformation.

  7. TIMP2 (show TIMP2 Antibodies) and TIMP3 play fundamental and differential roles in mediating pathological remodelling, independent from their MMP-inhibitory function

  8. Expansion of stem cells counteracts age-related mammary regression in compound Timp1 (show TIMP1 Antibodies)/Timp3-deficient mice.

  9. lack of TIMP3 increases inflammation and polarizes macrophages towards a more inflammatory phenotype resulting in increased atherosclerosis.

  10. TIMP-3 KO mice exhibit enhanced metabolism, as reflected by a higher body temperature than WT mice, possibly due to increased mitochondrial activity.

Pig (Porcine) TIMP Metallopeptidase Inhibitor 3 (TIMP3) interaction partners

  1. These results suggest the crucial role of TIMP-3 in successful implantation and embryo survival and indicate the endometrial stromal decidualization-like in pigs.

TIMP3 Antigen Profile

Protein Summary

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.

Gene names and symbols associated with TIMP3

  • metalloproteinase inhibitor 3 (CpipJ_CPIJ003282) antibody
  • TIMP metallopeptidase inhibitor 3 (TIMP3) antibody
  • Metalloproteinase inhibitor 3 (timp3) antibody
  • TIMP metallopeptidase inhibitor 3 (Timp3) antibody
  • TIMP metallopeptidase inhibitor 3 (timp3) antibody
  • tissue inhibitor of metalloproteinase 3 (Timp3) antibody
  • tissue inhibitor of metalloproteinase-3 (TIMP-3) antibody
  • HSMRK222 antibody
  • IMP-3 antibody
  • K222 antibody
  • K222TA2 antibody
  • SFD antibody
  • Timp-3 antibody
  • timp3 antibody
  • timp3-A antibody

Protein level used designations for TIMP3

metalloproteinase inhibitor 3 , TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) , tissue inhibitor metalloproteinase-3 , TIMP metallopeptidase inhibitor 3 , Metalloproteinase inhibitor 3 , MIG-5 protein , TIMP-3 , protein MIG-5 , tissue inhibitor of metalloproteinases 3 , tissue inhibitor of metalloproteinase-3 , tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) , tissue inhibitor of metalloproteinase 3 , 21 kDa protein of extracellular matrix , tissue inhibitor of metalloproteinases-3

GENE ID SPECIES
6034728 Culex quinquefasciatus
481289 Canis lupus familiaris
100135460 Papio anubis
100196821 Salmo salar
7078 Homo sapiens
100008690 Oryctolagus cuniculus
25358 Rattus norvegicus
282094 Bos taurus
100033947 Equus caballus
396483 Gallus gallus
373596 Xenopus laevis
574381 Macaca mulatta
100217407 Ovis aries
21859 Mus musculus
396775 Sus scrofa
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